About the Book
Table of Contents:
Contents
Introduction
Section I: The Body
Chapter 1: Cells—They Talk About Everything!
Chapter 2: Signals for Migrating White Blood Cells
Chapter 3: T cells—Masters of Immunity
Chapter 4: Capillaries—The “Brain Centers” of Tissue Development
Chapter 5: Platelets—Much More than a Plug
Chapter 6: Conversations in the Gut
Chapter 7: Signaling Across the Skin Landscape
Chapter 8: Cancer Cells—the Ultimate Manipulators
Section II: The Brain
Chapter 9: The World of Neurons
Chapter 10: The Supportive Role of Astrocytes
Chapter 11: Microglia—Master Regulators of the Brain
Chapter 12: The Myelin-Producing Oligodendrocytes
Chapter 13: Guardian Cells of the Brain
Chapter 14: Pain and Inflammation
Section III: The World of Microbe Communication
Chapter 15: Microbial Behavior and Conversations
Chapter 16: Battles Between Microbes and Human Cells
Chapter 17: Microbe Politics in the Gut
Chapter 18: Microbe Influences on the Brain
Chapter 19: The Complex World of Viruses
Chapter 20: Microbe-Plant Interactions
Chapter 21: Microbes’ Love-Hate Relationship with Cancer
Chapter 22: Microbial Conversations with Organelles
Section IV: Conversations Inside Cells
Chapter 23: Communication Among Organelles
Chapter 24: Mitochondrial Conversations
Chapter 25: Membrane Production
Chapter 26: Transporting Materials on Scaffolding Highways
Chapter 27: Dendritic Highways
Chapter 28: The Significance of Cilia
Chapter 29: Talking Molecules? The Case for mTOR
Concluding Our Tour of Cellular Conversations
Appendix
Acknowledgments
About the Author
Index
About the Author :
Jon Lieff, MD, brings to bear 40 years as a nationally recognized neuro-psychiatrist, during which he was president of a national medical subspecialty organization, founded a major scientific journal, and was the medical director for 25 years of a large network of psychiatric care for the elderly. He was a pioneer in several medical fields—geriatric psychiatry, brain injury, computer applications in psychiatry, and the integration of medicine, psychiatry, and neurology.
Starting with an interest in brain cell communication, Dr. Lieff found similar signaling among all cells in nature. Five years ago, he established his acclaimed and popular scientific website, Searching for the Mind, about the topic of cellular communication. With weekly posts, he reviewed and synthesized the latest scientific literature in neuroscience and cell biology.
Review :
"Using the common theme of 'cellular conversations,' this book covers an astonishing breadth of biological topics. By removing most of the 'impenetrable jargon' from his descriptions, geriatric psychiatry specialist Lieff succeeds in making the complex interactions between cells accessible for most readers."
—Choice Reviews
"The Secret Language of Cells takes us on an exciting journey into a world where we can visualize elaborate conversations among immune cells, brain cells, gut cells, bacteria, and even viruses. Dr. Lieff gives a wealth of examples for his thesis that this cellular signaling is the basis of life. It is a must-read for anyone seeking to understand modern biology and advanced medical science."
—Ray Kurzweil, inventor, author, and futurist
"The Secret Language of Cells explains the complex ways that cells in the body communicate and presents a new paradigm for understanding health and disease. It also suggests new possibilities for treatment and for promoting healing. I'm pleased that my former Harvard colleague, Jon Lieff, has written this important book."
—Andrew Weill, MD, director of the Andrew Weil Center for Integrative Medicine, professor at University of Arizona College of Medicine, and author
"Through a brilliant synthesis of cellular biology, microbiology, immunology, and neuroscience, TheSecret Language of Cells offers a lucid explanation of the marvelous intricacies of cellular life. The result is a masterful exploration of the profound implications of cellular intelligence for understanding pathophysiology, human health, and even our origins."
—William B. Miller, Jr., MD, physician, biologist, author of The Microcosm Within: Evolution and Extinction in the Hologenome, and internationally recognized expert on Cognition-Based Evolution
"Jon Lieff's description of cellular communication is insightful, provocative, illuminating, and engaging and provides deep and novel observations into the remarkable symphony of how life happens. Mimicking the cellular world he describes, Dr. Lieff is the great communicator and muse of living things. An inspiring and informative read."
—Ted Kaptchuk, professor of medicine at Harvard Medical School
"This journey into the dynamic realm of cellular conversations is a tour-de-force—fascinating, vital, and especially timely for understanding emerging viruses. As we learn about intelligence in smaller and smaller animals, it's not surprising that the tiniest creatures—microbes and even viruses—exhibit elaborate communication and complex decision making. Read The Secret Language of Cells!"
—Marc Bekoff, PhD, professor emeritus of ecology and evolutionary biology at the University of Colorado, Boulder and author of Canine Confidential: Why Dogs Do What They Do
"The Secret Language of Cells reveals how the micro world reflects the macro, alive with heroes and villains, shapeshifters and tricksters, vigilant guards and gullible bystanders, helpers that commit suicide for the common good and warriors that seize the day or collapse from exhaustion. Lieff's fascinating exploration inspires awe for the astonishing dialogues and clarion calls at the heart of the intelligence within."
—Antonia Felix, EdD, MFA, New York Times bestselling author
"Calling all physicians, microbiologists, medical students, and fellow science enthusiasts—you're going to love The Secret Language of Cells!This book reveals fascinating ongoing conversations between cells, bacteria, and viral particles that provide the basis for understanding growth, development, healthy biology, and pathology. Perhaps more importantly, they provide the blueprint for novel interventions, treatments, and cures for ailments ranging from chronic inflammatory diseases, to cancers and even viral infections. The COVID-19 pandemic has focused the world's lens on the world of microbes like never before. Read this book and join the conversation."
—Jill Grimes, MD, family physician, speaker, author, and educator
"The Secret Language of Cells is ideal for the education of medical and science students, as well as for practicing physicians. Dr. Lieff's remarkable synthesis of the scientific literature provides a current view of the intricate communication systems determining our physiology. He clearly explains how conversations among cells are the bridge between immunology, neuroscience, microbiology, and cancer research."
—Sharon Redd, MD, senior associate in anesthesia at Boston Children's Hospital and
assistant professor in anesthesia at Harvard Medical School
"In TheSecret Language of Cells, Dr. Lieff, brilliantly and effectively, communicates the complexities of modern biology to clinicians, and even laypeople, in understandable terms. In the process, he elucidates how communications between diverse varieties of cells determine our physical, mental, and emotional health, as well as the potential social implications."
—Sanford Finkel MD, founder of AAGP, cofounder of IPA and APA Council on Aging, and clinical professor of Psychiatry at University of Chicago Medical School
"Dr. Jon Lieff's The Secret Language of Cells is a tour-de-force . . . I highly recommend this fascinating book to science readers and anyone wanting to better understand the role and importance of cellular functions and communications in health and disease."
—George T. Grossberg, MD, director of Geriatric Psychiatry for the Department of Psychiatry & Behavioral Neuroscience at Saint Louis University School of Medicine
"Dr. Lieff has synthesized an extensive literature on the biological communications that underlie life into a highly accessible book. His integrative summary will appeal to a broad audience, from high school biology students to professionals with specific areas of expertise."
—Barnett Meyers, MD, professor emeritus at Weill Cornell Medical College of Cornell University
"The Secret Language of Cells makes it possible for a healthy dialogue between biology and philosophy, a step closer to making a bridge between life-science and various monistic and non-dual philosophies."
—Dr. Sthaneshwar Timalsina, professor for the Department of Religious Studies at San Diego State University
