About the Book
Commissioned by The American Association of Physicists in Medicine (AAPM) for their June 2015 Summer School, Proton Therapy: Physical Principles and Practice, this is the first AAPM monograph printed in full colour.
Proton therapy has been used in radiation therapy for over 70 years, but within the last decade its use in clinics has grown exponentially. This book fills in the proton therapy gap by focusing on the physics of proton therapy, including beam production, proton interactions, biology, dosimetry, treatment planning, quality assurance, commissioning, motion management, and uncertainties.
Chapters are written by the world's leading medical physicists who work at the pioneering proton treatment centers around the globe. They share their understandings after years of experience treating thousands of patients. Case studies involving specific cancer treatments show that there is some art to proton therapy as well as state-of-the-art science.
Even though the focus lies on proton therapy, the content provided is also valuable to heavy charged particle therapy. The book is tailored mainly to clinical physicists, who might use this as a textbook in the fast-growing field of proton therapy. Furthermore, this book provides up-to-date references to the scientific literature on each aspect of proton therapy covered in its 28 chapters. The book also includes an appendix of proton therapy nomenclature.
Table of Contents:
Introduction
Chapter 1
Introduction and History of Proton Therapy - Indra J. Das and Harald Paganetti
Chapter 2
The Practicing Clinician's Perspective on Proton Beam Therapy - Anthony Zietman
Chapter 3
Proton Beam Interactions: Basic - Hugo Palmans
Chapter 4
Proton Beam Interactions: Clinical - Indra J. Das, Alejandro Mazal, Ludovic De Marzi, and Vadim Moskvin
Chapter 5
Proton Relative Biological Effectiveness - Harald Paganetti
Technology
Chapter 6
Proton Beam Production and Dose Delivery Techniques - Marco Schippers
Chapter 7
Imaging for Proton Therapy - Katja Langen, Jerimy Polf, and Reinhard Schulte
Chapter 8
Field Shaping: Scattered Beam - Alejandro Mazal, Annalisa Patriarca, Claas Wessels, and Indra J. Das
Chapter 9
Field Shaping: Scanning Beam - X. Ronald Zhu, Falk Poenisch, Heng Li, Xiaodong Zhang,Narayan Sahoo, and Michael Gillin
Chapter 10
Secondary Radiation Production and Shielding for Proton Therapy Facilities - Nisy Elizabeth Ipe and C. Sunil
Dosimetry
Chapter 11
Detector Systems - Stanislav Vatnitsky and Hugo Palmans
Chapter 12
Dosimetry and Beam Calibration - Hugo Palmans and Stanislav Vatnitsky
Acceptance And Commissioning
Chapter 13
Acceptance Testing of Proton Therapy Systems - Jonathan B. Farr and Jon J. Kruse
Chapter 14
Clinical Commissioning of Proton Beam - Lei Dong
Operation
Chapter 15
Quality Assurance, Part 1: Machine Quality Assurance - Bijan Arjomandy
Chapter 16
Quality Assurance, Part 2: Patient-specific Quality Assurance - Bijan Arjomandy, Mark Pankuch, and Brian Winey
Chapter 17
Proton Therapy Workflow - Martijn Engelsman, Juliane Daartz, and James E. McDonough
Treatment Planning And Delivery
Chapter 18
Immobilization and Simulation - Jon J. Kruse
Chapter 19
Dose Calculations for Proton Beam Therapy: Semi-empirical Analytical Methods - Radhe Mohan, X. Ronald Zhu, and Harald Paganetti
Chapter 20
Dose Calculations for Proton Beam Therapy: Monte Carlo - Harald Paganetti, Jan Schuemann, and Radhe Mohan
Chapter 21
Uncertainties in Proton Therapy: Their Impact and Management - Radhe Mohan and Narayan Sahoo
Chapter 22
Treatment Plan Optimization in Proton Therapy - Jan Unkelbach, David Craft, Bram L. Gorissen, and Thomas Bortfeld
Chapter 23
Treatment Planning for Passive Scattering Proton Therapy - Heng Li, Annelise Giebeler, Lei Dong, Xiaodong Zhang, Falk Poenisch, Narayan Sahoo, Michael T. Gillin, and X. Ronald Zhu
Chapter 24
Treatment Planning for Pencil Beam Scanning - Tony Lomax, Alessandra Bolsi, Francesca Albertini, and Damien Weber
Chapter 25
Motion Management - Antje Knopf and Shinichiro Mori
Chapter 26
Monitor Unit (MU) Calculation - Timothy C. Zhu, Haibo Lin, and Jiajian Shen
Special Procedures
Chapter 27
Small Field Dosimetry: SRS and Eyes - Brian Winey and Marc Bussiere
Chapter 28
In Vivo Dosimetry for Proton Therapy - Narayan Sahoo, Archana Singh Gautam, Falk Poenisch, X. Ronald Zhu, Heng Li, Xiaodong Zhang, Richard Wu, Sam Beddar, and Michael T. Gillin
APPENDIX
Nomenclature and Terminology in Proton Therapy - Radhe Mohan and Harald Paganetti
