Vascular Cognitive Impairment

Vascular dementia is the second most common cause of dementia depending on geographical location, it accounts for 10-50% of cases of dementia. In recent studies the frequency of vascular dementia has been found to be higher than expected. Because vascular causes of cognitive impairment are common, may be preventable, and may benefit from therapy, early detection and accurate assessment of vascular cognitive impairment and vascular disease are important challenges for the practicing clinician. This book helps to address those challenges.

Table of Contents:
I: Conceptual Basis and Diagnostic Criteria 1. The Early History of Vascular Dementia 2. The Concept of Vascular Cognitive Impairment 3. Classification and Subtypes of Vascular Dementia 4. Diagnostic CriteriaII: Pathophysiology 5. Occurrence and Determinants of Vascular Cognitive Impairment 6. Genetic Factors 7. Large Vessel Pathology 8. Cerebral Small Vessel Disease: Pathological and Pathophysiological Aspects in Relation to Vascular Cognitive Impairment 9. White Matter Lessions 10. Overlap with Alzheimer's Disease 11. Neurotransmitter Control of the Cerebral Vasculature and Abnormalities in Vascular Dementia III: Clinical Features 12. Global Cognitive Syndromes 13. Focal Stroke Syndromes 14. Vascular Cognitive Impairment and Disability 15. Behavioural and Psychological Symptoms 16. Associated Neurological Features IV: Diagnosis17. The Neurological Examination in Aging, Dementia and Cerebrovascular Disease 18. Bedside Assessment of Vascular Dementia 19. General Approaches to Neuropsychological Assessment 20. Neuropsychological Examination of Executive Functions 21. Neuropsychological Examination of Memory 22. Language 23. Cognitive Outcome Measures in Vascular Dementia 24. Assessment of Behavioural Disturbances and Psychiatric Symptoms in Vascular Dementia 25. Evaluation of Daily Activities in Vascular Cognitive Impairment 26. Functional Brain Imaging 27. Structural Brain Imaging 28. Cerebrospinal Fluid Findings in Vascular Cognitive Impairment with Special Reference to Subcortical Vascular Dementia 29. Differential Diagnosis with Degenerative Dementias 30. Differential Diagnosis with Leukodystrophies and Non-vascular Acquired White Matter Disorders 31. The Mixed Dementias 32. Transcultural Problems in Clinical Assessment: Japan V: Course and Management 33. Natural History of Vascular Dementia 34. Staging: Relevance for Trial Design in Vascular Burden of the Brain 35. Prevention 36. Prevention and Treatment of Vascular Dementia 37. Pharmacotherapy of Mood and Behavior Symptoms 38. Early and Chronic Complications of Stroke 39. Regulatory Guidelines for Antidementia Drugs 40. Societal Burden and Pharmacoeconomics of Vascular Dementia 41. Vascular Cause of Cognitive Impairment - the Perspective

Review :
'This is an excellent and highly recommended book that wrestles with one of the toughest questions in the overlapping fields of stroke and dementia. This groundbreaking book signifies a change in approach and concept to the new ideas embodied in the new term "vascularcognitive impairment." The book is recommended to researchers and clinicians alike.' - Doody Publishing Review 'Anyone interested in finding out more about vascular cognitive impairment could do no better than read this book.' - International Journal of Geriatric Psychiatry