Adenosine, Cardioprotection and Its Clinical Application
Home > Medicine & Health Science textbooks > Clinical and internal medicine > Cardiovascular medicine > Adenosine, Cardioprotection and Its Clinical Application: (194 Developments in Cardiovascular Medicine)
Adenosine, Cardioprotection and Its Clinical Application: (194 Developments in Cardiovascular Medicine)

Adenosine, Cardioprotection and Its Clinical Application: (194 Developments in Cardiovascular Medicine)


     0     
5
4
3
2
1



International Edition


X
About the Book

It has been almost 15 years since the fIrst reports appeared indicating that adenosine exerted a .protective effect in ischemic and reperfused myocardium. Numerous experimental studies have shown that adenosine (both exogenous and endogenous adenosine) delays the onset of ischemic contracture, modulates myocardial metabolism during ischemia, attenuates reversible postischemic ventricular dysfunction (myocardial stunning), and reduces myocardial infarct size. Initial studies on adenosine's cardioprotective effect were based on its ability to stimulate postischemic ATP resynthesis, increase coronary blood flow, and reduce heart rate. Although these actions of adenosine are undoubtedly benefIcial to the ischemic/reperfused heart, it now appears that adenosine's cardioprotective effect may be exclusive of these properties. The immense growth in the number of articles on adenosine cardioprotection in the last several years has been related in large part to the hypothesis that adenosine plays a role in ischemic preconditioning. Ischemic preconditioning is the phenomenon in which a brief period of ischemia (and reperfusion) prior to a more prolonged occlusion reduces myocardial infarct size. This form of myocardial protection has received much interest because ischemic preconditioning has been shown to be the most potent means of reducing infarct size in all animal models thus far tested. In fact prior to studies implicating adenosine's role in ischemic preconditioning, adenosine's infarct reducing effect was not well recognized.

Table of Contents:
I. Adenosine and Cardioprotection.- 1. Adenosine and Cardioprotection.- II. Cardioprotection and Mechanisms of Ischemic and Reperpusion Injury.- 2. Concept of Cardioprotection Against Myocardial Ischemia.- 3. The Late Phase of Preconditioning Against Myocardial Stunning.- 4. Coronary Perfusion as the Major Determinant of Myocardial Contractility in the Heart: Implication for Myocardial Hibernation.- 5. Myocardial Protection From Reperfusion Injury With Adenosine.- III. Cellular Mechanisms of Cardioprotection in Ischemic Preconditioning.- 6. Protein Kinase C - the Key-Enzyme in Ischémic Preconditioning?.- 7. Adenosine, Cardioprotection and Potential Mechanisms.- 8. Activation of Ecto-5'-nucleotidase Mediates Cardioprotection in Ischemic Preconditioning: Important Role of Protein Kinase C.- 9. Role of Mn-SOD Induction in the Second Window Phenomenon of Preconditioning of Ischemic Hearts.- 10. Opioid Receptors, KATP Channels and Ischemic Preconditioning.- 11. Bradykinin and Preconditioning Against Infarction.- 12. Preconditioning in Human Muscle and Myocytes.- 13. Protein Kinase C and Adenosine Synergistically Activate ATP-Sensitive Potassium Currents: Implications for Ischemic Preconditioning.- Clinical Application of New Strategies to Protect The Ischemic Heart.- 14. Adenosine and Myocardial Protection in Humans.- 15. Clinical Applications of Ischemic Preconditioning.- 16. Clinical Pharmacology of Preconditioning and Adenosinergic Drugs.- 17. Clinical Application of Ischemic Preconditioning by ATP-Sensitive Potassium Channel Openers.- 18. Potassium Channel Openers and Cardiac Surgery.- 19. Anti-ischemic Effects of the ATP-sensitive Potassium Channel Opener During Coronary Angioplasty.- 20. Clinical Impact of Ischemic Preconditioning on Infarct Size and CoronaryNo-reflow Phenomenon after Successful Recanalization in the Acute Myocardial Infarction.


Best Sellers


Product Details
  • ISBN-13: 9781461346760
  • Publisher: Springer-Verlag New York Inc.
  • Publisher Imprint: Springer-Verlag New York Inc.
  • Height: 235 mm
  • No of Pages: 239
  • Returnable: N
  • Width: 155 mm
  • ISBN-10: 1461346762
  • Publisher Date: 05 Sep 2012
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Series Title: 194 Developments in Cardiovascular Medicine


Similar Products

Add Photo
Add Photo

Customer Reviews

REVIEWS      0     
Click Here To Be The First to Review this Product
Adenosine, Cardioprotection and Its Clinical Application: (194 Developments in Cardiovascular Medicine)
Springer-Verlag New York Inc. -
Adenosine, Cardioprotection and Its Clinical Application: (194 Developments in Cardiovascular Medicine)
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Adenosine, Cardioprotection and Its Clinical Application: (194 Developments in Cardiovascular Medicine)

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept

    New Arrivals


    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!