In Vitro Maturation of Human Oocytes

The use of IVM in assisted reproductive technology continues to increase around the world. The major benefit of IVM is that significant numbers of oocytes can be collected from ovaries without recourse to ovarian stimulation. This reduces the costs, time, and risks associated with conventional IVF. Although initially limited to women with polycystic ovary syndrome who were at higher risk of problems following ovarian stimulation, IVM is increasingly used in women with normal ovulatory menstrual cycles. This authoritative text covers the current scientific knowledge of oocyte development and the understanding behind the techniques involved in the clinical application of IVM in assisted reproductive technologies. Short Contents

Table of Contents:
Oocyte growth in the ovary. Interaction of oocytes and somatic cells. In-vitro development of small ovarian follicles. Mechanism of oocyte maturation. Gene expression during oocyte maturation. Epigenetic modification during oocyte maturation. Maturation of primordial follicles - the next step. Polycystic ovaries and polycystic ovary syndrome. Clinical aspects of polycystic ovary syndrome. Prediction and prevention of ovarian hyperstimulation syndrome. Clinical problems associated with ovarian stimulation (excluding OHSS). IVM for the treatment of infertility with PCOS. The first steps on the era of IVM. FSH priming in IVM cycles. Combination of FSH and hCG priming in IVM cycles. IVM oocyte collection - similarities and differences with IVF. Endometrial preparation for IVM. Laboratory aspects of IVM. Follow-up of children born after IVM. How do we improve implantation rate following IVM? Maturation of immature oocytes in stimulated cycles. IVM as an alternative for poor responders. IVM as an alternative for over-responders. Combination of natural cycle IVF with IVM. IVM for fertility preservation. Bibliographies & Index

Review :
"This book is suitable as a course textbook and indispensable for women's and gender studies programs. It is a necessary acquisition for academic libraries. Summing Up: Essential. Lower-level undergraduates and above; general readers."--CHOICE, G. M. Herrmann, SUNY College at Cortland, USA "Direct, clear, compelling, this volume could not be more articulate in exploding every myth associated with this transformative field. This volume is a must for an introductory women's studies course through to a capstone for WS majors; it both orients those new to the field, and provides excellent concrete advice for how to move from the college campus into the world."--Judith A. Howard, Sociology, University of Washington, USA "Transforming Scholarship will help students to think through the history and significance of the field of Women's and Gender Studies, guide them in answering challenging questions about themselves and their major or minor, and provide support and information about the job search and the ways they want to change the world. Rest assured that all Women's and Gender Studies majors at my school will be given a copy of this text"--Alison Piepmeier, Women's and Gender Studies, The College of Charleston, USA "What can you do with a major in women's studies?" How many times have I heard that question from students and parents! Thank goodness Michele Berger and Cheryl Radeloff have given us a thoroughly researched, accessible answer to that question. I'd highly recommend this book as required reading for first-year college students or as a great graduation gift for high school seniors interested in gender issues."--Susan M. Shaw, Women's Studies, Oregon State University, USA "If you have ever wondered what someone can do with a women's and gender studies degree, Transforming Scholarship is the book for you. Michele Berger and Cheryl Radeloff have assembled an invaluable resource for both teacher and students that provides practical and theoretical insights into this evolving and dynamic field."--Anne Lacsamana, Women's Studies, Hamilton College, USA