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Studies from the Rockefeller Institute for Medical Research Volume 12

Studies from the Rockefeller Institute for Medical Research Volume 12


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About the Book

This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1911 Excerpt: ...would, it is fair to assume, have been made two years earlier than it was. It was not until September, 1909, that we secured the spinal cord from two cases of infantile paralysis in human beings, which specimens were employed for the inoculation of monkeys by direct injection of an emulsion into the brain through a trephine opening. The first inoculations were successful. The animals immediately after their recovery from the ether anesthesia were lively and normal. They remained apparently in perfect health for a number of days, when paralysis set in. The spinal cord derived from these animals was and is still being employed to transmit the infection to still other monkeys. During the summer of 1909 Landsteiner and Popper published an account of a successful inoculation of two monkeys with the spinal cord derived from a case of infantile paralysis in a child. They employed the peritoneal cavity as the site of injection, which led to the development of paralysis, but in endeavoring to continue the transfer of the virus by intraperitoneal injection of other monkeys they failed entirely. Strauss and Huntoon in this country, who repeated in the late summer or early autumn of 1909 the experiments of Landsteiner and Popper, met with the same interruption of their work. Using the peritoneum as the avenue of entrance of the virus, they succeeded in producing paralysis in a monkey inoculated with the human cord, but failed to produce paralysis when they transferred to other monkeys a suspension of the spinal cord of the paralyzed monkey. In view of these experiments, and of still other similar ones made by different investigators, it is probable that the virus contained within the human cord is on the whole more active when implanted in the monkey than is the virus ...


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Product Details
  • ISBN-13: 9781130683080
  • Publisher: Rarebooksclub.com
  • Publisher Imprint: Rarebooksclub.com
  • Height: 246 mm
  • No of Pages: 220
  • Spine Width: 12 mm
  • Width: 189 mm
  • ISBN-10: 1130683087
  • Publisher Date: 01 Mar 2012
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Weight: 399 gr


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