Physiological Basis of Ventilatory Support: (Lung Biology in Health and Disease)

Defines the implementation of optimal management procedures for patients requiring respiratory assistance-heightening appreciation of the ventilator's significance in advanced life support while cautioning of potentially detrimental outcomes related to its improper or protracted use.

Table of Contents:
Physiology Underlying Ventilatory Support CONTROL OF BREATHING AND RESPIRATORY MUSCLE FUNCTION Control of Breathing Relevant to Mechanical Ventilation, Magdy Younes and Dimitris Georgopoulos Loaded Breathing and Dyspnea, Kieran J. Killian Muscle Function: Basic Concepts, Theodoros Vassilakopoulos, Spyros Zakynthinos, and Charis Roussos Assessment of Drive/Muscle Function, Rolf D. Hubmayr and Peggy M. Simon RESPIRATORY MECHANICS Mechanics of the Lungs and Chest Wall, Stephen H. Loring Surfactant and Mechanical Ventilation, Alan H. Jobe and Machiko Ikegami Assessment of Mechanics, Jason H. T. Bates Work of Breathing During Mechanical Ventilation, Catherine S. H. Sassoon and C. Kees Mahutte GAS EXCHANGE Distributions of Alveolar Ventilation and Pulmonary Blood Flow, Josep Roca and Roberto Rodriguez-Roisin The Effects of Mechanical Ventilation on Oxygen Delivery and Oxygen Consumption, James A. Russell Consequences of Mechanical Ventilation VENTILATION-RELATED CONSEQUENCES Patient-Ventilator Interactions: Dyssynchrony and Imposed Loads, Neil R. MacIntyre Ventilator-Induced Lung Injury: Mechanisms and Clinical Correlates, Lorraine N. Tremblay, Arthur S. Slutsky, Didier Dreyfuss, and Georges Saumon Dynamic Hyperinflation, John J. Marini Heart-Lung Interactions, Michael R. Pinsky NON-VENTILATION-RELATED CONSEQUENCES Upper Airway Dysfunction, John E. Heffner Conditioning of Inspired Gases, Maire P. Shelly Sedation and Paralysis During Mechanical Ventilation, Luciano Aguilera, Javier Alonso, Anton Arizaga, Thomas E. Stewart, and Jesus Villar Implementing Ventilatory Support INITIATING MECHANICAL VENTILATION Physiological Consequences of Intubation, Steven Deem and Michael J. Bishop Targets During Mechanical Ventilation, Keith G. Hickling Monitoring of the Mechanically Ventilated Patient, Robert Shapiro and Robert M. Kacmarek MODES OF VENTILATORY SUPPORT Full Ventilatory Support, Theodore W. Marcy Partial Ventilatory Support, Pierre Aslanian and Laurent J. Brochard PEEP and CPAP in Severe Airflow Obstruction, Andrea Rossi, Lorenzo Appendini, and Marco V. Ranieri Positive End-Expiratory Pressure in Acute Respiratory Failure: Pathophysiology and Practical Guidelines, Peter M. Suter and François Lemaire High-Frequency Ventilation: Principles and Practice, Sergio P. Ribeiro, Lorraine N. Tremblay, and Arthur S. Slutsky Noninvasive Positive-Pressure Ventilation in Patients with Acute Respiratory Failure, G. Umberto Meduri ADJUNCTIVE METHODS AND APPROACHES Extracorporeal Support of Gas Exchange, Antonio Pesenti, Michela Bombino, and Luciano Gattinoni Tracheal Gas Insufflation, Avi Nahum, John J. Marini, and Arthur S. Slutsky Pharmacological Approach to Hypoxemia in Patients with Acute Respiratory Distress Syndrome, Louis Puybasset and Jean-Jacques Rouby The Effect of Body Position on Perfusion, Ventilation, and Gas Exchange in Normal and Injured Lungs, Richard K. Albert Fluid Management and Bronchodilator Therapy During Mechanical Ventilation, David J. Pierson Liquid Ventilation, Burkhard Lachmann, Astrid Fraterman, and Serge J. C. Verbrugge Specific Problems in Ventilation Mechanical Ventilation in Severe Asthma, James W. Leatherman Barotrauma, Volutrauma, and the Ventilation of Acute Lung Injury, Marcelo B. P. Amato and John J. Marini Special Problems in Mechanical Ventilation, Robert W. Taylor and R. Philip Dellinger Discontinuation of Ventilatory Support, Amal Jubran and Martin J. Tobin Neonatal and Pediatric Ventilation: Physiological and Clinical Perspectives, Alison B. Froese Clinical Trial Issues in Mechanical Ventilation, Alan H. Morris and Deborah J. Cook

Review :
"It is a pleasure to encounter a well-edited and criticaly written volume intended for the most physiologically-oriented of respiratory practitioners.this volume merits a prominent place on the bookshelves of every investigator and teacher working in the field of respiratory care. "-Respiratory Care "The book is highly recommended to intensivists and certainly should be a welcome addition to departmental libraries. "- Anaesthesia and Intensive Care