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Home > Medicine & Health Science textbooks > Clinical and internal medicine > Diseases and disorders > Oncology > A Practical Guide to Human Cancer Genetics
A Practical Guide to Human Cancer Genetics

A Practical Guide to Human Cancer Genetics


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About the Book

This extensively updated and expanded edition provides the busy clinician with an essential overview of the latest developments in human cancer genetics--an area that has made significant advances since publication of the first edition. The opening section presents the principles of cancer genetics and introduces the basic concepts and mechanisms of tumorigenesis and inherited predisposition to cancer. The second part of the book provides information, on a systems basis, on the incidence, significance and management of predisposition to individual cancers. The final section deals with specific inherited cancer syndromes, giving practical guidance on clinical investigation, screening and management of affected patients and relatives at risk. The authors also provide up-to-date details of the genetic mapping of inherited cancer syndromes and the molecular genetic changes in individual cancers. Finally, an appendix provides a helpful revision guide to the fundamental principles of genetics. This practical and clear account will benefit clinicians and research workers in oncology, genetics, surgery and general medicine.

Table of Contents:
Foreword; Preface; Part I. General Principles of Cancer Genetics: Chromosomes and cancer; Molecular genetics of cancer; Genetic predisposition to cancer; Ethical issues in human cancer genetics; Part II. Genetics of Human Cancer by Site of Origin: Central nervous system; Eye; Cardiorespiratory system and thorax; endocrine system; Gastro-intestinal system; Reproductive system; Urinary system; Haematological and lymphoid neoplasia; Musculoskeletal system; Skin tumours and inherited disorders predisposing to skin tumours; Inherited conditions predisposing to dermatological malignancy; Part III. Inherited Cancer-Predisposing Syndromes: Appendix; Index.

Review :
'The book is an excellent and enjoyable to read. The amateur who is satisfied with certainly will drive more from it than the impartial professional seeking and challenge. For the majority of doctors and especially human cancer genetics the book succeeds as an example of the precept 'first do not harm'. Human Cancer Genetics book is a super textbook and should be in the library of every scientist interested in this subject.' Universitá degli Studi 'G. D'Annunzio' - Chieti ' … oncology departments would do well to have a copy to hand … it is clear that the authors are well informed … Anyone with an interest in the incidence, significance, associations and management of a particular cancer predisposition will likely benefit from reading the relevant information contained in this book.' Human Genetics 'This book is highly recommended as a reference source to students, practitioners, and specialists. It will serve as an excellent starting point to discuss genetic disorders with patients.' Paul P. Carbone, Oncology


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Product Details
  • ISBN-13: 9780521649612
  • Publisher: Cambridge University Press
  • Publisher Imprint: Cambridge University Press
  • Edition: Revised edition
  • Language: English
  • Returnable: N
  • Returnable: N
  • Spine Width: 23 mm
  • Width: 175 mm
  • ISBN-10: 0521649617
  • Publisher Date: 22 Jul 1999
  • Binding: Paperback
  • Height: 247 mm
  • No of Pages: 354
  • Returnable: N
  • Returnable: N
  • Weight: 602 gr


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A Practical Guide to Human Cancer Genetics
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A Practical Guide to Human Cancer Genetics
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