High-Throughput Analysis: A Tool for Combinatorial Materials Science

This book, edited by Potyrailo and Amis, addresses a new paradigm-shifting approach in the search for new materials-Combinatorial Materials Science. One way to consider such an approach is to imagine an adventurous chef who decides to look for new entrees by cooking food ingredients in many pots using different combinations in every pot, and boil­ ing, steaming, or frying them in various ways. Although most of the pots will not have the tastiest food ever devised, some recipes will taste intriguing, and some eventually will lead to a discovery of a new fascinating cuisine. Of course, having a skilled chef design the com­ binatorial formulation will certainly be helpful in ensuring a successful outcome. Similar to food, each engineering material is a complex product of its chemical composition, structure, and processing. Generally, each of these components matters---change one and you get another material. Most of these "new" materials will be less good than ones we use now since existing materials have been refined with the extensive work of scientists and engi­ neers. At the same time if one prepares diverse materials like our adventurous chef, chang­ ing material composition, processing conditions and time, etc. , some of these materials will be superior to existing ones and a few might represent breakout technology.

Table of Contents:
1 Elements of High-Throughput Analysis in Combinatorial Materials Science.- 2 Economic Impact of Combinatorial Materials Science on Industry and Society.- Optical Imaging And Spectroscopy.- 3 Image Analysis for High-Throughput Materials Science.- 4 Laser-Induced Fluorescence Detection in High-Throughput Screening of Heterogeneous Catalysts.- 5 Spectroscopic Imaging in the Mid-Infrared Applied to High-Throughput Studies of Supported Catalyst Libraries.- 6 Linear Spatially Encoded Combinatorial Chemistry with Fourier Transform Library Analysis.- Separations And Mass Spectrometry.- 7 Separation Approaches Toward Rapid and Complex Molecular Characterization of Diverse Polymers.- 8 High-Throughput Gas Chromatography and Mass Spectrometry for Heterogeneous Catalysis: Screening of Catalytic Activities and Selectivities.- 9 Rapid Determination of Molecular Parameters of Synthetic Polymers Using Precipitation-Redissolution HPLC and a “Molded” Monolithic Column.- 10 Ion Mobility/Time-of-Flight Analysis of Combinatorial Library Mixtures.- Sensors And Sensor Arrays.- 11 Acoustic Wave Sensors for High-Throughput Screening of Materials.- 12 High-Throughput Screening of Oxidation Catalysts with Gas Sensors.- 13 Optical Sensing Methods in High-Throughput Screening.- 14 Combinatorial Study and High-Throughput Screening of Transparent Barrier Films using Chemical Sensors.- 15 Intrinsic Fiber-Optic Sensors for Spatially Resolved Combinatorial Screening.- Analysis of mechanical, electrical, and Thermal properties.- 16 Diffusion Multiples for High-Efficiency Alloy Design.- 17 Combinatorial and Spread Techniques in the Fabrication of Organic-Based Photonic and Optoelectronic Devices.- 18 High-Throughput Conductivity Measurements of Thin Films.- 19 Development of High-Throughput Methodsfor Polymer Nanocomposite Research.- Electrochemical Analysis.- 20 Combinatorial Electropolymerization: Concept, Equipment, and Applications.- 21 Principles and Applications of Combinatorial Electrochemistry.- Combinatorial libraries, data management, and Scale-up of discovered materials.- 22 Ink-Jet Methods in Combinatorial Materials Synthesis.- 23 Miniaturized Reactor Concepts and Advanced Analytics for Primary Screening in High-Throughput Experimentation.- 24 A High-Throughput Cross-linker Evaluation for Polyurethane Dispersions.- 25 Data Management for Combinatorial Heterogeneous Catalysis: Methodology and Development of Advanced Tools.- 26 Scaling Up of Catalysts Discovered from Small-Scale Experiments.- 27 Combinatorial Development of Organic Clear Coatings for Plastic Substrates and Scale-Up of Combinatorial Leads.- About the Editors.

Review :
"This book should serve as a valuable resource for those graduate students, scientists, and engineers, who are interested in accelerating their research using combinatorial technologies." (J.J. Hanak, Ph.D.) "High-Throughput Analysis will serve as an invaluable resource for practitioners and new comers to the field. With the ingenuity and diligent efforts of scientists and engineers working in this field, I am convinced that combinatorial materials sciences will greatly enhance our understanding and ability to solve the problems of complex materials systems in the 21st century." (X.D. Xiang, Ph.D.) "With examples drawn from electronics, polymer chemistry, catalysis, biomaterials, metallurgy, and inorganic materials, this book reviews the state-of-the-art developments in analytical instrumentation that are critical to the success of combinatorial materials science. This book will be invaluable to industrial and academic scientists and engineers, as well as graduate students interested in the developments of sensors and other types of miniaturized analytical instrumentation for rapid characterization of materials on a combinatorial scale." (Scott C. Donnelly, Senior VP, GE Global Research, Schenectady, NY)