Applying Genomic and Proteomic Microarray Technology in Drug Discovery
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Applying Genomic and Proteomic Microarray Technology in Drug Discovery

Applying Genomic and Proteomic Microarray Technology in Drug Discovery


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About the Book

Microarrays play an increasingly significant role in drug discovery. Written by a leader in the field, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications. The author addresses the drawbacks, helping

Table of Contents:
QUANTITATIVE BIOLOGY: THE "OMICS" ERA Introduction Microarray Format General Utility The Omic Era Role of Gene Expression Microarrays in Drug Discovery Proteomics Today: The Great Challenge Potential Role for Protein Microarrays in Drug Discovery Critical Issues with Protein Microarrays Future medicine: Pharmacoproteomics or pharmacogenomics? References COMMERCIAL MICROARRAYS Introduction In situ arrays Ex situ or spotted arrays 3D and 4D chips Flow-Thru biochips note: flow-thru is a general term when applied here, remove TM. This should have also been corrected in the book proofs. Electronic biochips Future opportunities References SUPPORTS AND SURFACE CHEMISTRIES Introduction Substrates Summary References ARRAYING PROCESSES Introduction Creating spotted microarrays Printing parameters Protocols for printing nucleic acids Protocols for printing proteins References GENE EXPRESSION: MICROARRAY-BASED APPLICATIONS Introduction Applications demonstrating DNA microarray utility Biomedical research applications References PROTEIN MICROARRAY APPLICATIONS Introduction Spot theory Applications demonstrating protein microarray utility Measuring microarray performance Other microarray formats useful for proteomic applications References Index


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Product Details
  • ISBN-13: 9780203491133
  • Publisher: Taylor & Francis Inc
  • Publisher Imprint: CRC Press Inc
  • Language: English
  • No of Pages: 256
  • ISBN-10: 0203491130
  • Publisher Date: 03 Dec 2004
  • Binding: Digital (delivered electronically)
  • No of Pages: 256
  • Returnable: N


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