Polymorphism in Molecular Crystals: (14 International Union of Crystallography Monographs on Crystallography)

Polymorphism - the multiplicity of structures or forms - is a term that is used in many disciplines. In chemistry it refers to the existence of more than one crystal structure for a particular chemical substance. The properties of a substance are determined by its composition and by its structure. In the last two decades, there has been a sharp rise in the interest in polymorphic systems, as an intrinsically interesting phenomenon and as an increasingly important component in the development and marketing of a variety of materials based on organic molecules (e.g. pharmaceuticals, dyes and pigments, explosives, etc.). This book summarizes and brings up to date the current knowledge and understanding of polymorphism of molecular crystals, and concentrates it in one comprehensive source. The book will be an invaluable reference for students, researchers, and professionals in the field.

Table of Contents:
Preface 1: Introduction and historical background 2: Fundamentals 3: Controlling the polymorphic form obtained 4: Analytical methods for characterizing polymorphs 5: Conformational polymorphism - intra- and intermolecular energetics 6: Polymorphism and structure-property relations 7: Polymorphism of pharmaceuticals 8: Polymorphism in pigments and dyes 9: Polymorphism of high energy materials 10: Polymorphism and patents Bibliography Index

About the Author :
Prof. Joel Bernstein Department of Chemistry Ben-Gurion University of the Negev P.O. Box 653 Beer Sheva, Israel 84105 After obtaining a B.A. at Cornell University, he earned a Ph.D. in physical chemistry at Yale University for research on the solid-state spectroscopy of organic compounds. Following two-year postdoctoral stints in X-ray crystallography with the late Ken Trueblood at UCLA and in organic solid-state chemistry with the late Gerhardt Schmidt at the Weizmann Institute of Science in Rehovoth, Israel, he joined the faculty of the newly established Ben-Gurion University of the Negev, where he is now Professor of Chemistry. His research interests center on the organic solid state, with particular emphasis on understanding and utilizing polymorphism, structure-property relations, hydrogen-bonding patterns and graph sets, and organic conducting materials. His career has been punctuated by visiting professorships at the University of Illinois, Cornell University, the University of Minnesota and as a visiting scientist at the Cambridge Crystallographic Data Centre. He is a member of a number of professional organizations (American Chemical Society, American Crystallographic Association, Royal Society of Chemistry, Israel Chemical Society, Israel Crystallographic Society (served twice as president), European Crystallographic Association (served as vice president 1997-2000), American Association for the Advancement of Science (elected Fellow, 1999). He serves on the editorial board of six international journals.

Review :
`Review from previous edition Bernstein's book is a rich and comprehensive compilation and illustration of the structural variety of polymorphs and their properties.' ACA Book Reviews `An excellent resource book and a very good read ... can be recommended strongly both for content and interest.' Crystallographic Newsletter `Clear, vigorous, well-written and very readable ... Joel Bernstein's book represents the single most important source for the development of critical understanding of polymorphism and its commercial and industrial importance. ' Current Engineering Practice `It will be the book, for a long time to come, to which students and researchers will turn with confidence, as well as pleasure, in all questions of polymorphism in molecular crystals.' Structural Chemistry