Genetics: From Genes to Genomes 3.e

Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The Third Edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the new molecular discoveries that have changed the way the field of genetics is viewed.

Table of Contents:
1 Genetics: The Study of Biological Information2 Mendel's Breakthrough: Patterns, Particles, and Principles of Heredity3 Extensions to Mendel: Complexities in Relating Genotype to Phenotype4 The Chromosome Theory of Inheritance5 Linkage, Recombination, and the Mapping of Genes on Chromosomes6 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information7 Anatomy and Function of a Gene: Dissection Through Mutation8 Gene Expression: The Flow of Genetic Information from DNA to RNA to Protein9 Deconstructing the Genome: DNA at High Resolution10 Reconstructing the Genome Through Genetic and Molecular Analysis11 The Direct Detection of Genotype Distinguishes Individual Genomes12 Systems Biology and Proteomics13 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA14 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes15 The Prokaryotic Chromosome: Genetic Analysis in Bacteria16 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of Inheritance17 Gene Regulation in Prokaryotes18 Gene Regulation in Eukaryotes19 Cell-Cycle Regulation and the Genetics of Cancer20 Using Genetics to Study Development21 The Genetic Analysis of Populations and How They Evolve22 Evolution at the Molecular Level

About the Author :
Dr. Leland Hartwell is President and Director of Seattles Fred Hutchinson CancerResearch Center and Professor of Genome Sciences at the University of Washington.Dr. Hartwells primary research contributions were in identifying genes that controlcell division in yeast, including those necessary for the division process as well asthose necessary for the fi delity of genome reproduction. Subsequently, many of thesesame genes have been found to control cell division in humans and oft en to be thesite of alteration in cancer cells.Dr. Hartwell is a member of the National Academy of Sciences and has receivedthe Albert Lasker Basic Medical Research Award, the Gairdner FoundationInternational Award, the Genetics Society Medal, and the 2001 Nobel Prize inPhysiology or Medicine. Dr. Hood received an MD from the Johns Hopkins Medical Schooland a PhD in Biochemistry from the California Institute of Technology. His research interests include immunology, development and the development of biological instrumentation (e.g. the protein sequenator and the automated fluorescent DNA sequencer). His research played a key role in unraveling the mysteries of anitbody diversity. Dr. Hood has taught molecular evolution, immunology, molecular biology and biochemistry. he is currently the Chairman (and founder) of the cross-disciplinary Department of Molecular Biotechnology at the University of Washington. Dr. Hood has received a variety of awards including the Albert Lasker Award for Medical Research (1987), Dickson Price (1987), Cefas Award for Biochemistry (1989), and the Distinguished Service Award from the national Association of Teachers (1998). He is deeply involved in K-12 science educatiohn. His hobbies include running, mountain climbing, and reading. Dr. Michael Goldberg is a professor at Cornell University, where he teaches introductorygenetics and human genetics. He was an undergraduate at Yale Universityand received his Ph.D. in biochemistry from Stanford University. Dr. Goldberg performedpostdoctoral research at the Biozentrum of the University of Basel (Switzerland)and at Harvard University, and he received an NIH Fogarty Senior InternationalFellowship for study at Imperial College (England) and fellowships from theFondazione Cenci Bolognetti for sabbatical work at the University of Rome (Italy).His current research uses the tools of Drosophila genetics and the biochemical analysisof frog egg cell extracts to investigate the mechanisms that ensure proper cellcycle progression and chromosome segregation during mitosis and meiosis. Dr. Reynolds is an educator and author who has been teaching genetics and biology since 1990. An affiliate faculty member of the Genetics Department at the University of Washington, her research has included studies of gene regulation in E. coli, chromosome structure and DNA replication in yeast, and chloroplast gene expression in marien algae. She is a graduate of Mount Holyoke College and received her PhD from Tufts University. Dr. Reynolds was a post doctoral research fellow witht he Harvard University Department of Molecular Biology. Dr. Reynolds was also an author and producer of the laserdisc and CD-ROM Genetics: Fundamentals to Frontiers. Dr. Silver is a Professor at Princeton University in the Departments of Molecualr Biology, Ecology and Evolutionary Biology, and the program in Neuroscience. Dr. silver graduated from the University of Pennsylvania with BA and MS degrees in physics, and from Harvard University with a PhD in biophysics. He was a research fellow at the Sloan-Kettering Institute for Cancer Research and a seniro scientist at Cold Harbor Lab before coming to Princeton. He is the author of "Remaking Eden: Cloning and Beyond in a Brave New World." He is also the co-editor-in-chief of a new international journal entitled "Clining: Science and Policy," and co-editor-in-chief of "Mammalian Genome," the official journal of the International Mammalian Genome society. In 1993, Dr. Silver was elected a Fellow fo the AAAS. Ruth Veres is a science writer and editor with 25 years of experience in textbook publishing. She obtained her BA from Swarthmore college and MA degrees from Columbia University in NY and Tufts University. In addition to developing and editing more than 30 texts in the fields of political science, economics, psychology, nutrition, chemistry, and biology, she has co-authored a book on the immune system and an introductory biology text. She has also taught writing and languages at the Univ of California at Berkeley. She lives in San Francisco with her husband.