Trypanosomiases

This state-of-the-art reference book includes comprehensive coverage of the biology and control of African, Asian and South American trypanosomiasis ("sleeping sickness") in man and animals. It describes recent research developments in the biology and molecular biology of trypanosomes (the protozoan parasite) and their vectors, and methods in diagnosis and control, such as trapping tsetse fly vectors. Different sections of the book are devoted to biology of trypanosomes, vector biology, epidemiology and diagnosis, pathogenesis, disease impact, chemotherapy and disease control, and vector control. The book contains contributions from leading experts from Europe, North and South America, and Africa.

Table of Contents:
I: Preface II: List of Contributors SECTION 1: BIOLOGY OF TRYPANOSOMES 1: The Systematics of Trypanosomes of Medical and Veterinary Importance, J. Stevens, University of Exeter, UK, and S. Brisse, Institut Pasteur, France 2: Antigenic Variation, D. Barry, University of Glasgow, UK, and M. Carrington, University of Cambridge, UK 3: The African Trypanosome Genome, S.E. Melville, University of Cambridge, UK, P.A.O. Majiwa, International Livestock Research Institute, Kenya, and A. Tait, University of Glasgow, UK 4: Communication in Trypasomatids, D.P. Nolan, Trinity College, UK, J.A. Garcia-Salcedo, L. Vanhamme University of Brussels, Belgium, and E. Pays, Free University of Brussels, Belgium 5: Genetics and Molecular Epidemiology of Trypanosomes, G. Hide, University of Salford, UK, and A. Tait, University of Glasgow, UK SECTION 2: VECTOR BIOLOGY 6: Tsetse genetics: applications to biology and systematics, R. Gooding, University of Alberta, Canada, and E.S. Krafsur, Iowa State University, USA 7: Tsetse Population Dynamics, J.W. Hargrove, Harare, Zimbabwe 8: Tsetse Distribution, D.J. Rogers, University of Oxford, UK, and T.P. Robinson, FAO, Italy 9: Triatominae: systematics, morphology and population biology, J.P. Dujardin, Institut de Recherches pour le Development, France, and C.J. Schofield, London School of Hygiene and Tropical Medicine, UK SECTION 3: EPIDEMIOLOGY AND DIAGNOSIS 10: Diagnosis of Human African Trypanosomiasis, P. Buscher and V. Lejon, Institute of Tropical Medicine, Belgium 11: Epidemiology of Human African Trypanosomiasis, S.C. Welburn, and E.M. Fevre, University of Edinburgh, UK, P.G. Coleman, London School of Hygiene and Tropical Medicine, UK, and I. Maudlin, University of Edinburgh, UK 12: Diagnosis of Human South American Trypanosomiasis, A.O. Luquetti, Universidade Federal de Goiás, Brazil 13: Epidemiology of Human South American Trypanosomiasis, M.A. Miles, M. Yeo and M.W. Gaunt, London School of Hygiene and Tropical Medicine, UK 14: Diagnosis & Epidemiology of African Animal Trypanosomiasis, M. Eisler, University of Glasgow, UK, R. Dwinger, Ministry of Agriculture, The Netherlands, P. Majiwa, International Livestock Institute, Kenya, & K. Picozzi, University of Edinburgh, UK 15: Non-Tsetse-Transmited Animal Trypanosomiasis, A.G. Luckins, University of Edinburgh, UK, and R.H. Dwinger, Ministry of Agriculture, The Netherlands SECTION 4: PATHOGENESIS 16: Pathogenesis of Human African Trypanosomiasis, V.W. Pentreath, Salford University, UK, and P.G.E. Kennedy, Institute of Neurological Sciences, UK 17: Pathogenesis of Human South American Trypanosomiasis, E.R. Lopes, Universidade de Uberaba, Brazil, and E. Chapadeiro, Faculdade de Medicina do Triangulo Mineriero, Brazil 18: Pathogenesis of Animal Trypanosomiasis, K. Taylor, National Institute of Allergy & Infectious Disease, USA and E M-L Authie, Laboratoire de Recherches et de Coordination, sur les Trypanosomoses, France SECTION 5: DISEASE IMPACT 19: Medical Significance of Human South American Trypanosomiasis, G.A. Schmunis, Pan American Sanitary Bureau, USA 20: The Economics of African Trypanosomiasis,A.P.M. Shaw, A P Consultants, UK SECTION 6: CHEMOTHERAPY AND DISEASE CONTROL 21: Current Chemotherapy of Human African Trypanosomiasis C. Burri, Swiss Tropical Institute, Switzerland, A. Stich, Medical Mission Institute, Germany, and R.. Brun, Swiss Tropical Institute, Switzerland 22: Current Chemotherapy of Human South American Trypanosomiasis, A. Rassi, and A. Luquett, Universidade Federal de Goiás, Brazil 23: Current Chemotherapy of Animal Trypanosomiasis, P.H. Holmes, M.C. Eisler University of Glasgow, UK, and S. Geerts, Institute of Tropical Medicine, Belgium 24: Future Prospects in Chemotherapy for Trypanosomiasis, M.P. Barrett, G.H. Coombs and J.C. Mottram, University of Glasgow, UK 25: Trypanotolerance, M. Murray, University of Glasgow, UK, G.D.M. d'Ieteren, Societe des Grands Elevages du Bas-Congo Compagnie Pastorale du Haut-Lomami, Congo, and A.J. Teale, University of Stirling, UK 26: Control of Blood Transfusion Transmission of Human South American Trypanosomiasis, H. Moraes-Souza, Triangulo Mineiro Medicine School, Brazil, J. O Bordin and D.L. Junior, Universidade de Sao Paulo, Brazil SECTION 7: VECTOR CONTROL 27: Insecticidal Control of Tsetse, R. Allsopp, Albany, Australia, and B.H. Hursey, Wales, UK 28: Development of Bait Technology for Tsetse Control, G.A. Vale, Harare, Zimbabwe, and S.J. Torr, University of Greenwich, UK 29: The Application of Bait Technology to Control Tsetse, P. Van den Bossche and R. D. Deken, Prince Leopold Institute of Tropical Medicine, Belgium 30: Community Participation in Tsetse Control, R.D. Dransfield, and R. Brightwell, InfluentialPoints.com, UK 31: Control of Triatominae, J.C.P. Dias, Oswaldo Cruz Foundation, Brazil and C.J. Schofield, London School of Hygiene and Tropical Medicine, UK 32: The Sterile Insect Technique as a Component of Areawide Integrated Pest Management of Tsetse U. Feldmann, International Atomic Energy Agency, Austria 33: Biting Flies: their role in the Mechanical Transmission of Trypanosomes to Livestock and Methods for their Control, M.J.R. Hall, The Natural History Museum, UK, and R. Wall, University of Bristol, UK