In Vitro Toxicity Testing of Environmental Agents
Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Pharmacology > Medical toxicology > In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities Part A: Survey of Test Systems
In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities Part A: Survey of Test Systems

In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities Part A: Survey of Test Systems

|
     0     
5
4
3
2
1




Out of Stock


Notify me when this book is in stock
About the Book

These two volumes contain the papers presented at a North Atlantic Treaty Organization (NATO) Advanced Study Institute held on September 22-28, 1979 in Monte Carlo, Monaco. The conference was entitled "In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities." This international conference presented an opportunity for the participants to exchange informa­ tion and ideas on the current approaches (both scientific and po­ litical) for toxic assessment of environmental agents. The poten­ tial health effects of these compounds as well as future needs in the environmental research field were discussed. The scientific content of the conference seminars included an overview of the various cellular, subcellular, organ, animal, and genetic systems which have been used to assess the health effects of environmental agents. The scientific principles behind short­ term assays and an evaluation of their applicability to health effects monitoring and analysis were investigated. Included among major topics were: (1) the biochemistry and pharmacology of selected environmental agents; (2) molecular mechanisms of car­ cinogenesis, mutagenesis, and transformation; (3) bacterial muta­ genesis and toxicity; (4) mammalian cell mutagenesis, toxicity, and transformation; (5) in vitro carcinogens and mutagens; (6) teratogenic and other developmental toxic effects; and (7) the development of short-term neuro-behavioral toxicity assays.

Table of Contents:
A: Survey of Test Systems.- I. Mutagenesis Testing: Prokaryotic Systems.- Molecular Mechanisms of Mutagenesis and Chromosomal Carcinogenesis: A Suimnary Review.- Molecular Principles Underlying the Ames Salmonella/Microsome Test: Elements and Design of Short-Term Mutagenesis Tests.- Bacillus subtilis Rec-Assay With and Without Metabolic Activation: Improvements and Applications.- A Simple, Forward Selection Scheme for Independently Determining the Toxicity and Mutagenic Effect of Environmental Chemicals: Measuring Replica- tive Killing of Escherichia coli by an Integrated Fragment of Bacteriophage Lambda DNA.- The Use of Salmonella Bacteriophage P22 To Study the Multiple Mechanisms of Acridine-Induced Damage.- II. Mutagenesis Testing: Eukaryotic Systems.- Use of a Ciliated Protozoan as a Model System To Detect Toxic and Carcinogenic Agents.- In Vivo Assay To Screen for Mutagens/Carcinogens in the Nematode C. elegans.- The Maize-Microbe Bioassay: A Unique Approach to Environmental Mutagenesis.- Mutagenicity of Ambient Air at Selected Sites in the United States Using Tradescantia as a Monitor.- Tradescantia Micronuclei (TRAD-MCN) Test for Environmental Clastogens.- Metabolic Activation and Mutagenic Properties of Procarcinogens in Drosophila.- Mammalian Cell Mutagenesis: Relevance for Detection of Environmental Mutagens/Carcinogens.- Quantitative Mammalian Cell Mutagenesis and Mutagen Screening: Study With Chinese Hamster Ovary Cells.- III. In Vitro Carcinogenesis Testing.- In Vitro Carcinogenesis With Cell Lines.- Modulation of Induced Quantitative Mammalian Cell Transformation.- Chemical Carcinogenesis In Vitro: Limitations and Possibilities in the Use of Rat Liver Epithelial Cells for Screening Carcinogens.- IV. Neurobehavioral Toxicity Testing.- Behavioral Assays in environmental Toxicology.- Prenatal Exposure to Environmental Chemicals as a Test System for Neurotoxicology.- Mechanisms in Heavy Metal Toxicity.- Use of Cultures of Neuroblastoma and Glioma as a Model System To Study the Heavy Metal-Induced Neurotoxicity.- Neurochemical Approaches to Toxicity Testing: Artificial Food Dyes.- In Vitro Approaches to Neurotoxicity--A Physiologist’s Perspective.- V. End-Organ Toxicity Testing.- Migration Inhibition of Alveolar Macrophages: An Assay System for Evaluating Toxicity of Pollutant Chemicals.- Environmental Factors in Renal Disease.- Indexes (Combined for Part A and Part B volumes).- Author Index.


Best Sellers


Product Details
  • ISBN-13: 9780306411236
  • Publisher: Springer Science+Business Media
  • Publisher Imprint: Kluwer Academic/Plenum Publishers
  • Language: English
  • Returnable: Y
  • ISBN-10: 0306411237
  • Publisher Date: 01 Jan 1983
  • Binding: Hardback
  • No of Pages: 553
  • Sub Title: Current and Future Possibilities Part A: Survey of Test Systems


Similar Products

Add Photo
Add Photo

Customer Reviews

REVIEWS      0     
Click Here To Be The First to Review this Product
In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities Part A: Survey of Test Systems
Springer Science+Business Media -
In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities Part A: Survey of Test Systems
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities Part A: Survey of Test Systems

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept

    New Arrivals

    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!