Gamete Interaction
Gamete Interaction: Prospects for Immunocontraception

Gamete Interaction: Prospects for Immunocontraception

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About the Book

Brings together contributions from experts involved with all aspects of reproductive research and discusses how an immune-type response to inhibit conception might be induced via an antigen vaccine. The coverage provides a thorough description of the sperm-egg surface domain interactions in fertilization, with specific emphasis on the influence of antibodies and gamete-specific antigens in preventing or enhancing conception. Individual chapters deal with a broad range of subjects pertaining to the fertilization reaction and each is followed by a short discussion clarifying or expanding upon the ideas presented.

Table of Contents:
Sperm antigens - defining sperm surface domains, D.Myles et al; epididymal and seminal plasma-related leads - immunologic cytokines and reproduction, D.Anderson; sperm-zona interaction - sperm acrosin and binding to the zona pellucida, E.Topfer-Petersen et al; zona pellucida antigens - development and maturation of the zona pellucida, A.Sacco; antibodies as analytical tools and immunogens - development of human-human antisperm monoclonal antibodies, M.Kurpisz; the use of molecular biology for antigen production - molecular biological approaches for antigen production, W.Chin; evaluating gamete antigens - anti-sperm assays, W.Jones; contraceptive vaccine development - strategy of vaccine development, D.Griffin; immunosafety aspects of fertility control vaccine, G.Ada.


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Product Details
  • ISBN-13: 9780471568476
  • Publisher: John Wiley and Sons Ltd
  • Publisher Imprint: John Wiley & Sons Inc
  • Height: 58 mm
  • Weight: 1304 gr
  • ISBN-10: 0471568473
  • Publisher Date: 01 Jan 1990
  • Binding: Hardback
  • Sub Title: Prospects for Immunocontraception
  • Width: 35 mm


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