About the Book
This book covers a number of engineered nanotheranostics platforms and nanomedicines applications of FDA-approved medicines for early-stage diagnosis and treatment of cancer. The book focuses on (i) the basic design and bioengineering of safe medicines, (ii) physicochemical understanding of surface engineered medicines and their characteristics, (iii) various examples for site-specific bioimaging and multimode therapies, (iv) stimuli-responsive approaches for targeted drug delivery applications, (v) targeted therapeutics approaches for cancer cells or solid tumor ablations, (vi) targeted mechanisms of administrative biomedicines, (vii) impact of surface modification or engineering of biomedicines for site-selective tumor binding ability, and (vii) requirements for clinical trials and FDA approval. The content of this book appeal to readers who are interested in recent developments of FDA-approved cost-effective rapid cancer imaging and therapeutic platforms.
Table of Contents:
Introduction to cancer therapies.- Nanoceria based polymeric composite for theranostic applications.- Functional nanomaterials for bio-sensing applications.- Graphene quantum dots for cancer bioimaging, biosensing and therapy.- "All‐in‐one” nanoparticles for trimodality imaging‐guided intracellular photo‐magnetic hyperthermia therapy under intravenous administration.- State of the art in integrated biosensors for organ-on-a-chip applications.- Nanotherapeutics for Rheumatoid Arthritis Therapy.- Biosensors and Point‐of‐Care Devices for Bacterial Detection: Rapid Diagnostics Informing Antibiotic Therapy.- Nanostructured electrodes as electrochemical biosensors for biomedical applications.- Functional nanomaterials for diagnosis and therapy of male infertility.- Microscopic and spectroscopic characteristic of functional materials.- Functional Biomaterials for targeted drug delivery applications.- Functional materials for multimode therapeutics of solid tumor.- Biomaterials and emerging cancer therapies targeting Tumor Microenvironment.- Next-generation therapies for breast cancer.- Materials for molecular bio-imaging: methods and their characteristics.- Degradation, toxicity and clinical assessment of functional biomedicine.- Clinical validations of localized cancer nanomedicine.- Nano-scavengers in near infrared light mediated photothermal cancer therapy.- Polymer-Drug conjugates: An emerging platform for targeted drug delivery.- Functional biomedicine for image guided therapeutics of solid tumor.
About the Author :
Madhusudhan Alle is currently working as Postdoc Fellow at The University of Memphis, TN, USA. Earlier he worked as Research Professor at Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, South Korea (2018-2022), and also worked as Associate Professor at Department of Chemistry, Gondar University, Gondar, Ethiopia (2014-2018). During this period, he served as Coordinator of M.Sc. (Chemistry) Programs and as Head of the Chemistry Department. Four students submitted their master's thesis under his supervision. He received his doctorate from Department of Chemistry, Osmania University, India (2013), where he worked on the research projects sponsored by University Grants Commission, India. He has more than 20 years of experience in teaching and research in both academia and industry. He has published more than 70 scientific papers in SCI/SCIE-grade journals^2000 citations; h-index = 23) as First and Corresponding Author and published1 book and 11 chapters (Springer and Elsevier).
Shiv Dutt Purohit is currently working as International Research Professor (Assistant Professor) at the School of Chemical Engineering, Yeungnam University, Gyeongsan, South Korea. He obtained his Ph.D. from the Department of Polymer and Process Engineering, Indian Institute of Technology Roorkee, in 2021. He is Materials Scientist, and his research interests lie in biomedical and related areas such as tissue engineering and wound healing. Besides, he is also intrigued to work in other areas such as food packaging materials. He has published more than 20 research articles and chapters and has more than 500 citations on his name with an h-index of 10. He is also Reputed Reviewer for several peer-reviewed international journals and working as Academic Editor for Scientifica-Hindawi. He is also involved in the editing of a few special issues in SCIE journals.
Rajendra Prasad is currently working as Assistant Professor at the School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi, India. Prior to this position, Rajendra Prasad had postdoctoral trainings from Tufts University, Medford, Boston, MA, USA, NOVA Medical School, Faculdade de Ciências Médicas Campo Mártires da Pátria, Lisboa, Portugal and Technion-Israel Institute of Technology, Haifa, Israel, and Indian Institute of Technology, Bombay, India, in the area of Cancer NanoMedicine and targetable cancer theranostics. Moreover, Rajendra Prasad had a chance to help few master students during my postdoctoral trainings, which gave me a confidence to handle scientific challenges and lead independent research projects. Rejendra Prasad has also cracked prestigious Postdoctoral Fellowships such as IPDF, PBC, and JSPS and hold my membership for Royal Society of Chemistry.
Azamal Husen served as Professor and Head of the Department of Biology, University of Gondar, Ethiopia, and is Foreign Delegate at Wolaita Sodo University, Wolaita, Ethiopia. Previously, he was Visiting Faculty of the Forest Research Institute and the Doon College of Agriculture and Forest at Dehra Dun, India. His research and teaching experience of 20 years encompasses the biogenic nanomaterial fabrication and application, plant responses to nanomaterials, plant adaptation to harsh environments at the physiological, biochemical, and molecular levels, herbal medicine, and clonal propagation for improvement of tree species. To his credit are over 200 publications; and he is Editor-in-Chief of the American Journal of Plant Physiology. He is also working as Series Editor of 'Exploring Medicinal Plants', published by Taylor & Francis Group, USA; 'Plant Biology, Sustainability, and Climate Change', published by Elsevier, USA; and 'Smart Nanomaterials Technology', published by Springer Nature Singapore Pte Ltd. Singapore.
