Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases
Home > Medicine & Health Science textbooks > Pre-clinical medicine: basic sciences > Physiology > Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases
Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases

Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases


     0     
5
4
3
2
1



International Edition


X
About the Book

This book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable sourcefor beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members.

Table of Contents:
Module 1. Overview of G-Protein coupled receptor.- Module 2. TGR5 receptor.- Module 3. P2Y receptor.- Module 4. Therapeutically Targeting TGR5 & P2Y receptors. 

About the Author :
Dr. Senthilkumar Rajagopal, is an Assistant professor at Rayalaseema University, Kurnool, AP, India and obtained his Ph.D. in Biochemistry from Annamalai University, INDIA.  He did his post-doctoral research in Anesthesiology in University of Virginia, Virginia, followed by Department of Cancer Immunology & AIDS, Dana Farber Cancer Institute, Harvard University, MA, USA and, Department of Physiology and Biophysics, Virginia Commonwealth University, Virginia, USA.  He is a recipient of Rameshwardasji Birla Smarak Kosh Endowment award from Mumbai Medical Trust, Mumbai, INDIA and Ramalingaswami Re-entry Fellowship from Department of Biotechnology, Ministry of Science and Technology, Government of India.  He has more than 10 years of research experience in various fields such as Alcoholic hepatotoxicity, voltage gated calcium channels, and protein kinase C phosphorylation, ADAM family, Smooth muscle physiology, G-protein coupled receptor signaling pathways, Neurotransmitters transporters to central nervous system.  He has published nearly 48 research articles in various peer-reviewed international journals, 18 book chapters, and presented a research articles in number of conferences, proceedings and attended various workshops/seminars.  He is on the editorial/reviewer board in many peer-reviewed international journals such as Frontiers in Cellular Neuroscience, American Journal of Biochemistry and Molecular Biology, Neuroscience, etc.  He is member of various prestigious scientific associations like Indian Society for Atherosclerosis Research (ISAR), The International Science Congress Association (ISCA), Society of Biological Chemistry (SBC), Society for Free Radical Research India (SFRR), The Indian Society of Cell Biology (ISCB) and member of American Association of Pharmaceutical Scientists (AAPS) and Science Advisory Board (SAB).  Dr. Murugavel Ponnusamy is presently working as Postdoctoral Research Associate at the Center for Developmental Cardiology, Institute for Translational Medicine, Qingdao University, China. Previously, he had worked as Postdoctoral fellow at the Division of Renal Diseases, Department of Medicine, Rhode Island Hospital, Brown University-Alpert Medical School, USA, under the supervision of Dr. Shougang Zhuang. His research interest includes molecular pharmacology, cellular signaling, tissue repair and regeneration, and experimental therapeutics. Currently, he is research interest is focused on the influence of non-coding RNAs in cardiovascular disorders. His Ph.D. research was focused on elucidating the effect of diallyl tetrasulfide on cadmium-induced toxicity (an in vivo and in vitro study), which was carried at Annamalai University, India. Till, now, he has published more than 40 research articles in various international peer-reviewed journals and contributed five chapters to different books. He is an active member of various societies including theSociety of Biological Scientists of India (SOBSI), Indian Society of Cell Biology (ISCB), and Society of Biological Chemists (SBC) India.


Best Sellers


Product Details
  • ISBN-13: 9789811315701
  • Publisher: Springer Verlag, Singapore
  • Publisher Imprint: Springer Verlag, Singapore
  • Height: 235 mm
  • No of Pages: 76
  • Returnable: Y
  • ISBN-10: 9811315701
  • Publisher Date: 27 Nov 2018
  • Binding: Hardback
  • Language: English
  • Returnable: Y
  • Width: 155 mm


Similar Products

Add Photo
Add Photo

Customer Reviews

REVIEWS      0     
Click Here To Be The First to Review this Product
Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases
Springer Verlag, Singapore -
Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept

    New Arrivals


    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!