Buy Solvent-Dependent Flexibility of Proteins and Principles of Their Function
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Home > Mathematics and Science Textbooks > Chemistry > Organic chemistry > Solvent-Dependent Flexibility of Proteins and Principles of Their Function: (2 Advances in Inclusion Science)
Solvent-Dependent Flexibility of Proteins and Principles of Their Function: (2 Advances in Inclusion Science)

Solvent-Dependent Flexibility of Proteins and Principles of Their Function: (2 Advances in Inclusion Science)


     0     
5
4
3
2
1



Available


X
About the Book

Molecular biology has now advanced to the point where it is no longer possible to give a complete review of the available data on the conformational features of proteins. New data keep streaming in, and there is obviously an urgent need for some sort of general treatment of the subject. A systematic treatment of the large amount of data obtained by a great variety of methods on a great variety of objects must be based on the use of models; these should be as simple as possible, should conform to well-established scien- tific laws, and at the same time be sufficiently flexible. The validity of the models finally arrived at is then confirmed or otherwise by testing the conclusions arrived at with their aid by means of experiment. After a suitable model has been adopted, it can be used in analyzing the experimental data. Such an analysis may result in one of three possible situations: neither the experi- mental results nor their interpretation contradict the proposed model; the experimental results do not contradict the proposed model but their interpretation by the authors does; finally, both the experimental results and their interpretation may be found to be incompatible with the fundamental principles underlying the proposed model. The first situation is clearly the most desirable, and presents no difficulties.

Table of Contents:
1 / The Properties of Water.- 1.1. Pure Water.- 1.2. Water in Model Systems.- 2 / Principles and Implications of the Dynamic Model of Behavior of Proteins in Aqueous Media.- 2.1. Description of the Properties of Proteins in Terms of the Dynamic Model.- 2.2. A Description of the Properties of Membranes in Terms of the Dynamic Model.- 3 / Conformational Mobility of Proteins.- 3.1. Studying Hydrated Biopolymers by IR Spectroscopy.- 3.2. Fundamental Principles of Hydrogen Exchange Method.- 3.3. Results Obtained by Hydrogen Exchange and Proteolytic Studies.- 3.4. Fundamental Principles and Applications of the NMR Method.- 3.5. Gamma-Resonance Spectroscopy and its Applications.- 3.6. The Method of Spin Label and its Application.- 3.7. Application of Luminescence to the Study of Protein Dynamics.- 3.8. Results of X-Ray Diffraction Studies of Protein Mobility.- 4 / Interaction Between Proteins and Water.- 4.1. Hydration of Biopolymers and Methods of its Study.- 4.2. Protein Cavities (Clefts) and their Interaction with Water.- 4.3. The Dynamics of Water-Protein Interaction.- 5 / Effect of Perturbing Agents on the Dynamic Properties of Proteins.- 5.1. Changes in the Conformation and Stability of Proteins Brought about by Perturbing Agents.- 5.2. Effect of Temperature on Protein Dynamics and on the Interaction between the Protein and the Surrounding Solvent.- 5.3. Ultrasonic Action.- 6 / Dynamic Model of Association and Dissociation of Specific Complexes.- 6.1. Effect of Complex Formation on the Stability of the Protein.- 6.2. Effect of Complex Formation on Dynamic Properties of Proteins.- 6.3. Immunoglobulins.- 6.4. Cytochrome c.- 6.5. Myoglobulin.- 6.6. Hemoglobin.- 7 / Dynamic Model of Protein Behavior and Mechanism of Enzymatic Function.- 7.1. A Possible Connection between theKinetic and Conformational Properties of Enzymes.- 7.2. Comparison between the Dynamic Model of Enzymatic Activity and Other Models of Enzymatic Catalysis.- 7.3. Relaxational Properties of Enzymes.- 7.4. Effect of Perturbing Agents on Enzymatic Activity.- 7.5. Action of D2 O on Enzymes.- 7.6. Glyceraldehyde-3-Phosphate Dehydrogenase.- 7.7. Transaminase.- 7.8. Myosin.- 7.9. Lysozyme.- 7.10. ?-Chymotrypsin and Pepsin.- 7.11. Study of Reactions Involving Papain at Low Temperature.- 7.12. Allosteric Enzymes.- 8 / Interactions between Macromolecules of Different Types and Proteins and Cells in Aqueous Media.- 8.1. Effect of Polymers on the Flexibility of Antibodies in Complex with Spin-labeled Hapten at Different Temperatures.- 8.2. Effect of Proteins on the Flexibility of Antibodies and Oxyhemoglobin.- 8.3. Effect of Thermality Induced Transitions of Human Serum Albumin on the Mobility of the Subunits of Spin-labeled Oxyhemoglobin.- 8.4. Effect of Polymers and Proteins in Different Ligand States of Active Sites on the Properties of the Solvent.- 8.5. Interaction between Serum Proteins and Cells.- Conclusion.- References.- Index of Authors.- Index of Subjects.

Review :
'This work will prove to be useful to all workers involved in advanced studies on protein interactions, enzymatic reactions and protein purification. It is recommended to all protein chemists, immunochemists and molecular biologists.' Preparative Biochemistry (1985)



Product Details
  • ISBN-13: 9789401087988
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Height: 235 mm
  • No of Pages: 350
  • Returnable: N
  • Width: 155 mm
  • ISBN-10: 9401087989
  • Publisher Date: 13 Oct 2011
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Series Title: 2 Advances in Inclusion Science


Similar Products

Add Photo
Add Photo

Customer Reviews

REVIEWS      0     
Click Here To Be The First to Review this Product
Solvent-Dependent Flexibility of Proteins and Principles of Their Function: (2 Advances in Inclusion Science)
Springer -
Solvent-Dependent Flexibility of Proteins and Principles of Their Function: (2 Advances in Inclusion Science)
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Solvent-Dependent Flexibility of Proteins and Principles of Their Function: (2 Advances in Inclusion Science)

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept


    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!