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Advances in Biomedical Applications of Photochemistry and Photobiology

Advances in Biomedical Applications of Photochemistry and Photobiology


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About the Book

A new compilation of critical reviews, this time on the subject of Photobiology and Photomedicine, is presented to specialists and professionals in general interested in this field. This volume appears under the title of 'Advances in Biomedical Applications of Photochemistry and Photobiology'. To publish this work a selected group of distinguished specialists was invited to critically review the latest advances in this relatively new area of research. The purpose of this volume of the series is to keep researchers and medical practitioners abreast of the latest developments, both in the theoretical aspects and in the practical applications of photodynamic treatment of disease, as well as in phototoxicity of drugs. The volume comprises 9 chapters. In addition to the contributions from our laboratory a group of worldwide contributors from different countries; Venezuela, Italy, Spain, Norway, France, The Netherlands, Canada and India, report on the achievements in their own and related areas of research. The topics addressed in this book include: clinical applications of phototherapy, different aspects of photosensitization and applications of singlet oxygen, the importance of cell density and cell-to-cell interactions in photodynamic treatment and photofrin mediated photodynamic therapy, physical aspects of the excited states, photochemical mechanism of DNA, damage induced by new furocoumarin and photo induced toxicity by 5-aminolevulinic acid. Hence, all three important aspects of light interaction with cells in the presence of an external chemical agent, namely toxicity, therapy and photo physical properties of the substrates involved in the interaction, are discussed in this volume. In this way an overall picture of the field is offered to the readers. Contents: Clinical applications of phototherapy ; Advantages and disadvantages in the application of photosensitizer in photomedicine; Generation and photobiological implications of singlet oxygen; Photosensitizing drugs and respiratory burst in neutrophils; Importance of cell density and cell-to-cell interactions in photodynamic treatment; Interactions of drugs with human serum albumin studied by fluorescence spectroscopy; Photophysics of melatonin and its precursors; Photochemical mechanism of DNA damage induced by furocoumarin; Molecular mechanisms of in vitro photofrin-mediated Photodynamic Therapy.


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Product Details
  • ISBN-13: 9788177361223
  • Publisher: Research Signpost
  • Publisher Imprint: Research Signpost
  • Height: 230 mm
  • ISBN-10: 8177361228
  • Publisher Date: /05/2002
  • Binding: Paperback


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