Membrane Interacting Peptides and Proteins - Bookswagon UAE
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Membrane Interacting Peptides and Proteins

Membrane Interacting Peptides and Proteins


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About the Book

A biological membrane is one of the most exiting but also one of the most complex mediums existing in the kingdom of life, and in spite of constant progress in resolving structure of membrane associated protein and/or peptides, only a few structures have been solved at the atomic level. This book is a compilation of review articles written by specialists in their research domains and contains chapters which are devoted to the most recent developments of biophysical methods such as NMR, Atomic Force Microscopy or neutron diffraction, applied for structural identification of membrane embedded proteins and on the use of phospholipids as support for functional peptides. It also contains chapters describing conformational transitions which may occur upon uptake by membrane media of water soluble proteins, together with some cares which have to be taken when analyzing data obtained in membrane mimicking media. Finally, the book also contains two chapters devoted to the design of membrane interacting peptides which can act as cell penetrating peptides for the intracellular delivery of biologically active molecules. Together with the references cited in the various chapters, although excluding crystal structure identification, this book can provide a good insight of the possibilities of structural investigations of membrane interacting peptides and proteins. Contents: Interactions of proteins and peptides with membrane components: Structural consequences; Carrier peptides: Promising tools for a broad range of applications; Neutron and X-ray studies of lipid bilayers; The study of biomolecular-membrane interactions using surface plasmon resonance spectroscopy; Investigations of membrane-associated polypeptides by solid-state NMR spectroscopy; Probing lipid-lipid, lipid-peptide and lipid protein interactions with the atomic force microscope; Plant cysteine-rich antimicrobial proteins that interact with biological membranes; Oriented gramicidin M-gramicidin A heterodimers: Rectification decreases with increased ion concentration; Solution structure of antimicrobial peptides with a b-hairpin fold; Stucture activity relationships; Cell penetrating peptides and their applications for drug and gene delivery.


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Product Details
  • ISBN-13: 9788177361049
  • Publisher: Research Signpost
  • Publisher Imprint: Research Signpost
  • Height: 230 mm
  • ISBN-10: 817736104X
  • Publisher Date: /05/2002
  • Binding: Paperback


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