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Home > Medicine & Health Science textbooks > Medicine: general issues > Doenças fúngicas, sistema imunitário e polimorfismos de nucleótido único
Doenças fúngicas, sistema imunitário e polimorfismos de nucleótido único

Doenças fúngicas, sistema imunitário e polimorfismos de nucleótido único


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About the Book

As infecções fúngicas estão associadas à mortalidade e à morbilidade. Parecem estar a aumentar nos dias de hoje em resultado do aumento dos estados de imunodeficiência, como se verifica no VIH/SIDA, no cancro e no tratamento do cancro, e na imunossupressão após o transplante. Os fungos são omnipresentes e as doenças que causam podem ser superficiais e triviais, alérgicas ou mais profundas e potencialmente fatais. A maioria das pessoas imunocompetentes é capaz de controlar e conter estas infecções. O sistema imunitário do hospedeiro determina assim o resultado clínico das infecções fúngicas. As variações genéticas influenciam as respostas individuais aos agentes patogénicos e às doenças. Foi descrita uma série de susceptibilidades genéticas a infecções fúngicas. Foi demonstrado que os polimorfismos de nucleótido único (SNP) influenciam as respostas individuais a doenças, medicamentos, produtos químicos, agentes patogénicos e vacinas. A interleucina-6 (IL6) é uma citocina pró-inflamatória importante na imunidade a infecções fúngicas. Estudos associaram SNPs no gene IL6 aos níveis circulantes de IL6. Diferentes genótipos de IL6 e os níveis circulantes da citocina foram investigados em diferentes indivíduos para determinar a influência dos SNP na suscetibilidade a infecções fúngicas.


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Product Details
  • ISBN-13: 9786208652234
  • Publisher: Edicoes Nosso Conhecimento
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Height: 229 mm
  • No of Pages: 88
  • Returnable: N
  • Weight: 181 gr
  • ISBN-10: 6208652235
  • Publisher Date: 16 Feb 2025
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Spine Width: 5 mm
  • Width: 152 mm


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