Variations dans les protéines et les gènes
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Home > Mathematics and Science Textbooks > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > Variations dans les protéines et les gènes: un rôle dans l'asthme bronchique ?
Variations dans les protéines et les gènes: un rôle dans l'asthme bronchique ?

Variations dans les protéines et les gènes: un rôle dans l'asthme bronchique ?


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About the Book

YKL-40: une protéine de la famille des chitinases est connue pour être associée à l'inflammation. Le rôle des polymorphismes nucléotidiques simples du gène CHI3L1 dans la susceptibilité à l'asthme et les niveaux de YKL-40 a été largement étudié sur différents groupes ethniques, et des résultats contradictoires ont été obtenus concernant l'allèle de susceptibilité. Dans le présent travail, la technologie de résonance plasmonique de surface et des méthodes basées sur la réaction en chaîne par polymérase ont été utilisées pour estimer les niveaux de protéines et le génotypage. Nos résultats suggèrent fortement une association entre les taux de YKL-40 et la gravité de l'asthme, ainsi qu'une association probable entre le génotype CG au niveau de la région promotrice rs4950928 du gène CHI3L1 et des taux élevés de YKL-40 et la susceptibilité à l'asthme.


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Product Details
  • ISBN-13: 9786202001717
  • Publisher: Editions Notre Savoir
  • Publisher Imprint: Editions Notre Savoir
  • Height: 229 mm
  • No of Pages: 112
  • Returnable: N
  • Sub Title: un rôle dans l'asthme bronchique ?
  • Width: 152 mm
  • ISBN-10: 6202001712
  • Publisher Date: 29 Jul 2025
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Spine Width: 7 mm
  • Weight: 209 gr


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