Signal Transduction in Affective Disorders
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Clinical psychology > Signal Transduction in Affective Disorders
Signal Transduction in Affective Disorders

Signal Transduction in Affective Disorders


     0     
5
4
3
2
1



International Edition


X
About the Book

Recent progress in brain science has been remarkable, especially with regard to advances in the area of neuroscience. Particularly in the past decade, there have been many important discoveries about signal transduction in the brain. With this background, biological research in affective disorders has become well developed in relation to neural signaling. However, this field is fairly hard to understand comprehensively, and there is relatively little integrative work with clinical psychiatry in spite of the involvement of a wide variety of scien­ tific disciplines. This monograph brings together up-to-date reviews from several young Japanese scientists who work in basic and clinical neuroscience. The intention is to explain in plain language the information that has evolved on signal transduction in terms of the biological abnormalities and mechanisms of anti­ depressants. The model shown on the cover (and on page 24) is intended to help the reader understand signal transduction in the brain and the patho­ physiology of affective disorders as well as the mechanisms of antidepressants.

Table of Contents:
Effects of Antidepressants on Transmembrane Signaling.- Role of G Proteins in Signal Transduction.- Effects of Chronic Administration of Antidepressants on Signal Transduction.- The Phospholipase C System in Affective Disorders.- Targets for Antidepressants.- References.- Serotonergic and Noradrenergic Neuromodulation in the Hippocampus and the Mechanism of Action of Antidepressants.- Pathophysiological Model of Affective Disorders and Monoaminergic Function.- Development of Novel Antidepressants and Their Pharmacological Profiles.- Modulation of Serotonergic Neurotransmission by SSRIs.- Convergence of Serotonergic and Noradrenergic Neurotransmission: Neurodynailiic Viewpoint.- Conclusion.- References.- Serotonin-2A Receptor Function in Affective Disorders.- Role of 5-HT2A Receptor Function in Etiology of Affective Disorders.- Calcium Mobilization and Affective Diosorders.- Mechanism of 5-HT2A Receptor Hyperfunction.- Conclusion.- References.- Immunological Aspects of Mood Disorders: Interaction Between Cytokines and Intracellular Calcium Signaling.- Immunological Dysfunction in Mood Disorders.- Stress and Immunological Function.- Alteration of Immune Function and Mood.- Cytokines and Nitric Oxide Pathway.- Cytokines and Calcium Function.- Conclusion.- References.- The Role of G Proteins in the Pathophysiology and Treatment of Affective Disorders.- Changes in the Biological Hypotheses for the Pathophysiology of Manic-Depressive Illness.- Antidepressants and G Proteins.- Receptor Reconciliation Theory of the Action of Antidepressants.- Postmortem Study in Affective Disorders.- Postnatal Developmental Changes of G Protein in Human Brains.- Imbalance Hypothesis of G-Protein Function in Affective Disorders.- Selectivity of Treatment Drugs in the Light of Signal Transduction.- Conclusion.- References.- Protein Phosphorylation System in the Mechanism of Action of Antidepressants.- Protein Phosphorylation Systems.- cAMP-Dependent Phosphorylation System.- Effect of Antidepressant Treatment on the PKA System.- Effect of Antidepressant Treatment on Phosphorylation of Substrate Proteins for PKA.- Effect of Antidepressant Treatment on Phosphorylation of MAP2.- Effect of Antidepressant Treatment on Microtubule Assembly.- Conclusion.- References.- Stress and BDNF Signal Transduction: Implications for Stress-Related Psychiatric Disorders.- Physiological Functions of BDNF.- Regulation of BDNF Expression.- BDNF Signal Transduction Cascade.- Stress-Induced Hippocampal Cellular Damage.- Stress and BDNF.- Co-Administration of a Phosphodiesterase Inhibitor and the Response to Selective Norepinephrine Reuptake Inhibitor.- Conclusion.- References.- Postreceptor Signal-Transduction Systems as Potential Targets of Lithium.- Lithium and Postreceptor Signal-Transduction.- Conclusion.- References.- Participation of Cytoskeletal Elements in Neuronal Signal Transduction: New Insight into the Molecular Basis of Antidepressant Action.- Tubulin, G Proteins, and Adenylyl Cyclase Signal Transduction.- Tubulin - G Protein Interaction.- Cytoskeletal Elements and Antidepressant Drugs.- References.- In Vivo Investigations of Signal-Transduction Systems in Affective Disorders by Magnetic Resonance Spectroscopy.- Which Metabolites in Signal-Transduction Systems Can Be Measured by MRS?.- Clinical Applications of MRS to the Study of Signal-Transduction Systems.- Conclusion.- References.


Best Sellers


Product Details
  • ISBN-13: 9784431702108
  • Publisher: Springer Verlag, Japan
  • Publisher Imprint: Springer Verlag, Japan
  • Language: English
  • Returnable: Y
  • ISBN-10: 4431702105
  • Publisher Date: 01 Jan 1998
  • Binding: Hardback
  • No of Pages: 146
  • Returnable: Y


Similar Products

Add Photo
Add Photo

Customer Reviews

REVIEWS      0     
Click Here To Be The First to Review this Product
Signal Transduction in Affective Disorders
Springer Verlag, Japan -
Signal Transduction in Affective Disorders
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Signal Transduction in Affective Disorders

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept

    Fresh on the Shelf


    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!