About the Book
All the tissues of the eye, including the lens, the cornea, the ciliary body, the neuroretina and the retinal pigment epithelium must work in harmony for the realization of clear vision.The phenotypic emergence of each of these tissues requires intercellular communication, which is achieved through direct physical contact as well as through diffusion and reception of the molecular beacons.This volume provides an overview of the molecular and cellular biology of eye development and encompasses themes like early gene expression in the surface ectoderm and the optic cup, retinal neurogenesis, signaling molecules and axonal guidance. It presents new findings on the influence of the lens on the development of the visual system and how gene expression in the optic cup controls differentiation of the lens fiber cell while established ideas about the morphogenesis of the ciliary body are challenged. A valuable source of information for developmental biologists and neurobiologists as well as ophthalmologists interested in understanding the relationship between temporally and spatially regulated gene activity and function and cellular interactions in early development and neuronal functions.
Table of Contents:
Preface: Bhat, S.P.; Expression of FoxE4 and Rx Visualizes the Timing and Dynamics of Critical Processes Taking Place during Initial Stages of Vertebrate Eye Development: Zllinski, C.; Brownell, I; Hashimoto, R.; Medina-Martinez, O.; Swindell, E.C.; Jamrich, M.; The Lens Has a Specific Influence on Optic Nerve and Tectum Development in the Blind Cavefish Astyanax. Soares, D.; Yamamoto, Y.; Strickler, A.G.; Jeffery, W.R.; The Involvement of Neural Retina Pax6 in Lens Fiber Differentiation: Reza, H.M.; Yasuda, K.; Pax-6 Expression in Posthatch Chick Retina during and Recovery from Form-Deprivation Myopia: Bhat, S.P.; Rayner, S.A.; Chau, S.C.; Ariyasu, R.G.; Transplantation of Neural Progenitor Cells into the Developing Retina of the Brazilian Opossum: An in vivo System for Studying Stem/Progenitor Cell Plasticity: Sakaguchi, D.S.; Van Hoffeien, S.J.; Theusch, E.; Parker, E.; Orasky, J.; Harper, M.M.; Benediktsson, A.; Young, M.J.; The Role of Hedgehog Signaling in the Development of the Zebrafish Visual System: Stadler, J.A.; Shkumatava, A.; Neumann, C.J.; Wnt/Frizzled Signaling during Vertebrate Retinal Development: Van Raay, T.J.; Vetter, M.L.; Ciliary Neurotrophic Factor Promotes Muller Glia Differentiation from the Postnatal Retinal Progenitor Pool: Gourea, O.; Rhee, K.D.; Yang, X.-J.; MARCKS in Advanced Stages of Neural Retina Histogenesis: Zolessi, F.R.; Arruti, C.; 5A11/Basigin Gene Products Are Necessary for Proper Maturation and Function of the Retina: Ochrietor, J.D.; Linser, P.J.; 'One Receptor' Rules in Sensory Neurons: Mazzoni, E.O.; Despian, C.; Celik, A.; Long-Term Treatment of the Developing Retina with the Metabotropic Glutamate Agonist APB Induces Long-Term Changes in the Stratification of Retinal Ganglion Cell Dendrites: Deplano, S.; Gargini, C.; Maccarone, R.; Chalupa, L.M.; Bisti, S.; Emergence of Realistic Retinal Networks in Culture Promoted by the Superior Colliculus: Collcos, M.A.; Firth, S.I.; Bosze, J.; Goldstein, J.; Feller, M.B.; The RB Protein Family in Retinal Development and Retinoblastoma: New Insights from New Mouse Models: Bremner, R.; Chen, D.; Pacal, M.; Livne-Bar, I.; Agochiya, M.; Distinct Capacities of Individual E2Fs to Induce Cell Cycle Re-Entry in Postmitotic Lens Fiber Cells of Transgenic Mice: Chen, Q.; Liang, D.; Yang, T.; Leone, G.; Overbeek, P.A.; Deregulation of Lens Epithelial Cell Proliferation and Differentiation during the Development of TGF[beta]-Induced Anterior Subcapsular Cataract: Lovicu, F.J.; Ang, S.; Chorazyczewska, M.; McAvoy, J.W.; Looking at an Oft-Overlooked Part of the Eye: A New Perspective on Ciliary Body Development in Chick: Hyer, J.; Author Index; Subject Index.
