Histopathology of Nodal and Extranodal Non-Hodgkin’s Lymphomas
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Histopathology of Nodal and Extranodal Non-Hodgkin’s Lymphomas

Histopathology of Nodal and Extranodal Non-Hodgkin’s Lymphomas


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About the Book

During the 10 years since the last edition of Histopathology of Non-Hodgkin's Lymphomas, based on the updated Kiel classification, our knowledge on malignant lymphomas, especially on extranodal lymphomas, has increased. This volume - Histopathology of Nodal and Extranodal Non-Hodgkin's Lymphomas - is an expanded and completely revised edition, now based on the WHO classification. The parallels to the updated Kiel classification and the REAL classification are indicated. The information is organized in organ-specific chapters, comprising the well-known nodal lymphoma entities as well as all known extranodal lymphomas and the different organ-specific clinico-pathological entities: lymphomas of the spleen, the gastrointestinal tract, the skin, etc. In addition to the morphology, the major immunohistochemical, molecular genetic, and clinical data are included in each chapter.

Table of Contents:
1 History of Lymphoma Classification.- 1.1 Introduction.- 1.2 The Kiel Classification.- 1.3 The REAL Classification Proposal.- 1.4 The WHO Classification.- References.- 2 Current Status of Lymphoma Classification.- 2.1 Introduction.- 2.2 Small- and Large-Cell Versus Low- and High-Grade.- 2.3 Primary Versus Secondary Lymphoma.- 2.4 Definition of Immunocytoma and Its Border with Marginal Zone B-Cell Lymphoma.- 2.5 Indistinct Border Between Nodal Marginal Zone B-Cell Lymphoma and Follicular Lymphoma with Marginal Zone Differentiation.- 2.6 Grading of Follicular Lymphoma.- 2.7 Distinction Between Diffuse Large B-Cell Lymphoma and Burkit’s Lymphoma: Reproducibility and Value of Subclassification.- 2.8 Problems in Reproducibly Recognizing Anaplastic Large-Cell Lymphoma and Lymphoblastic Lymphoma on Purely Morphological Grounds.- 2.9 Is Peripheral T-Cell Lymphoma, Unspecified a Distinct Clinicopathological Entity or a Catchall Term?.- 2.10 Neither the WHO nor the EORTC Classification of Cutaneous Lymphoma Covers Today’s Knowledge.- References.- 3 Epidemiology.- 3.1 Introduction.- 3.2 Statistical Data of the Kiel Lymphoma Registry.- References.- 4 Nodal B-Cell Lymphoma.- 4.1 Precursor B-Cell Lymphoblastic Leukemia.- 4.2 Peripheral B-Cell Lymphoma.- References.- 5 Nodal and Leukemic NK/T-Cell Lymphoma.- 5.1 Precursor T-Lymphoblastic Leukemia/Lymphoma.- 5.2 Peripheral NK/T-Cell Lymphoma.- References.- 6 Extranodal Lymphoma.- 6.1 Introduction.- 6.2 Gastrointestinal Lymphoma.- 6.3 Lymphoma of the Upper Aerodigestive Tract.- 6.4 Malignant Lymphoma of the Major Salivary Glands.- 6.5 Lymphoma of the Eye, Lachrymal Glands, and Orbit.- 6.6 Lymphoma of the Mediastinum.- 6.7 Lymphoma of the Lung.- 6.8 Lymphoma of the Pleura.- 6.9 Lymphoma of the Heart.- 6.10 Splenic Lymphoma.- 6.11Lymphoma of the Liver.- 6.12 Lymphoma of the Breast, Reproductive, and Urinary Systems.- 6.13 Endocrine Gland Lymphoma.- 6.14 Cutaneous Lymphoma.- 6.15 Lymphoma of Soft Tissues.- 6.16 Lymphoma of the Bone.- 6.17 Lymphoma of the Central Nervous System.- 6.18 Intravascular Large-B-Cell Malignant Lymphoma.- References.- 7 Plasma Cell Proliferations.- 7.1 Plasma Cell Myeloma/Bone Marrow Plasmacytoma.- 7.2 Extraosseous (Extramedullary) Plasmacytoma.- 7.3 Associated Diseases.- 7.4 Heavy-Chain Diseases.- References.- 8 Lymphoma Occurring in a Setting of Immunodeficiency.- 8.1 Lymphoproliferative Disorders Associated with Congenital Immunodeficiencies.- 8.2 Lymphoma and Lymphoproliferative Disorders Associated with Acquired Immunodeficiency.- References.- 9 Practical Guidelines for Lymphoma Diagnosis in Bone Marrow.- 9.1 Patterns of Involvement.- 9.2 Associated Lesions or Modifications.- 9.3 Diagnosis of Bone Marrow Involvement According to the Different Types of Lymphoma.- 9.4 Differential Diagnosis.- References.- 10 Practical Advice: Methods for the Diagnosis of Malignant Lymphoma.- 10.1 The Diagnosis of Malignant Lymphoma.- 10.2 Immunohistochemistry and Molecular Clonality Analysis in the Diagnosis of Lymphoma.- References.

Review :
From the reviews: "Dr. Alfred Feller and Dr. Jacques Diebold have presented us with succinct descriptions and high quality Giemsa-stained photomicrographs ... . Their most valuable contribution, however, is their discussion of unresolved problems of classification ... . The authors also bring attention to significant unresolved problems in the WHO classification, including thought-provoking discussions of ... . are to be congratulated for a job well done and for a most enjoyable and personal approach to the complex problems of lymphomas." (Maurice P. Barcos, Oncology Intl. J. Cancer Research and Treatment, Vol. 67(5-6), 2004) "Feller and Diebold's book is not only based on the WHO classification of lymphoma, but also mirrors its presentation ... . then follows something really good: a section specifically addressing, and indeed called, differential diagnosis. ... Another good feature of this book is its inclusion of organ-specific sections, for example, lymphoma of the lung ... . I liked this book. It is not simply a catalogue of lymphomatoid diseases. I think it will be practically useful." (Dr. D. Wright, ACP News, 2005)


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Product Details
  • ISBN-13: 9783642622243
  • Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
  • Publisher Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • Edition: Revised edition
  • Language: English
  • Returnable: N
  • ISBN-10: 3642622240
  • Publisher Date: 19 Aug 2012
  • Binding: Paperback
  • Height: 242 mm
  • No of Pages: 428
  • Width: 193 mm


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