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Home > Medicine & Health Science textbooks > Medicine: general issues > Medical equipment and techniques > Medical research > Regulation of Sertoli Cell and Germ Cell Differentiation: (181 Advances in Anatomy, Embryology and Cell Biology)
Regulation of Sertoli Cell and Germ Cell Differentiation: (181 Advances in Anatomy, Embryology and Cell Biology)

Regulation of Sertoli Cell and Germ Cell Differentiation: (181 Advances in Anatomy, Embryology and Cell Biology)


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About the Book

The intention of the present monography is to shed more light on the regulation of Sertoli cell and germ cell differentiation. Involving knockout and transgenic mouse models, the authors focus on male factor infertility that might be related to altered maturation of Sertoli cells, male factor infertility that might be due to incorrect histone-to-protamine exchange in haploid spermatids, and progression of testicular germ cell cancer that might be favoured by an aberrant Sertoli cell germ cell communication.

Table of Contents:
Spermatogenesis.- Organization of the seminiferous epithelium.- Synchronization of spermatogenesis.- Regulation of spermatogenesis.- The Sertoli cell.- Origin and maturation of the Sertoli cell.- Altered Sertoli cell differentiation in testicular disorders.- Differentiation markers of the Sertoli cell.- Sertoli cell intercellular communication.- Knockout and transgenic mouse models and mutations in man.- The differentiation of male germ cells.- The regulation of gene expression during prespermatogenesis.- The regulation of gene expression during spermatogenesis.- Idiopathic male infertility: impaired histone-to-protamine exchange?- Male infertility caused by incorrect transcriptional regulation.- Male infertility caused by incorrect translational regulation.- Male infertility caused by incorrect chromatin condensation.- Carcinoma-in-situ of the testis and testicular germ cell tumour: impaired intercellular communication due to altered Sertoli cell differentiation?- Carcinoma-in-situ of the testis and testicular germ cell tumour.- Sertoli cell differentiation in seminiferous tubules infiltrated with carcinoma-in-situ of the testis.- Role of gap junctional intercellular communication in carcinogenesis.- Role of gap junctional intercellular communication in the development of carcinoma-in-situ of the testis to testicular germ cell tumour.- References.- Subject index.


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Product Details
  • ISBN-13: 9783540257509
  • Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
  • Publisher Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • Height: 235 mm
  • No of Pages: 95
  • Returnable: N
  • Width: 155 mm
  • ISBN-10: 3540257500
  • Publisher Date: 16 Sep 2005
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Series Title: 181 Advances in Anatomy, Embryology and Cell Biology


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Regulation of Sertoli Cell and Germ Cell Differentiation: (181 Advances in Anatomy, Embryology and Cell Biology)
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Regulation of Sertoli Cell and Germ Cell Differentiation: (181 Advances in Anatomy, Embryology and Cell Biology)
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