Symposium on Pathology of Axons and Axonal Flow: Organized by the Österreichische Arbeitsgemeinschaft für Neuropathologie and the Research Group of Neuropathology of the World Federation of Neurolo(5 Acta Neuropathologica Supplementa)

Advances in axon biology are so rapid that every year provides us with a wealth of new facts and observations; hence, this conference cannot reasonable be expected to answer all questions. Rather, its purpose must be to take stock of the available data, to communicate advances and new concepts, and to help us to formulate the goals and approaches for future research. To this end, ample time was allotted during the symposium for discussion, but these exchanges of thoughts cannot, unfortunately, be included in the printed text. We hope that publication of the presentations will provide a valuable source of information on the present state of knowledge on this most important borderland between neuro- pathology, neurophysiology and neurochemistry. We would like to express our gratitude to all participants of the symposium for contributing their efforts and for their enthusiasm. We are also indebted to Springer Verlag and Bergmann Verlag for publication of the symposium and for their appreciation of the editorial concerns.

Table of Contents:
Neuroaxonal Dystrophy in Man: Character and Natural History.- Neuropathological Conditions Related to Neuroaxonal Dystrophy.- Infantile Neuroaxonal Dystrophy or Seitelberger’s Disease: II. Peripheral Nerve Involvement. Electron Microscopy Study in one Case.- How Long Can Degenerating Axons in the Central Nervous System Produce Reactive Changes? An Electron Microscopic Investigation.- Fine Structural Changes of Neurites in Alzheimer’s Disease.- Mitochondrial Changes in Axonal Dystrophy Produced by Vitamin E Difficiency.- Permeability of Blood Vessels and Connective Tissue Sheaths in the Peripheral Nervous System to Exogenous Proteins.- Changes in Axonal Flow During Regeneration of Mammalian Motor Nerves.- Nuclear, Cytoplasmic and Axoplasmic RNA in Experimental Neuroaxonal Dystrophy.- The Dependence of Fast Transport in Mammalien Nerve Fibers on Metabolism.- Slow and Rapid Transport of Protein to Nerve Endings in Mouse Brain.- Transport of S-100 Protein in Mammalian Nerve Fibers and Transneuronal Signals.- Dynamic Condition of Protein in Axons and Axon Terminales.- Effect of Nerve Section on Protein Metabolism of Ganglion Cells and Preganglionic Nerve Endings.- Some Observations on the Experimental Production of Acute Neuroaxonal and Synaptosomal Dystrophy.- Independence of the Rapid Axonal Transport of Protein from the Flow of Free Amino Acids.- Acetylcholinesterase in Mammalian Peripheral Nerves and Characteristics of its Migration.- Role of Slow Axonal Transport in Nerve Regeneration.- Axoplasmic Streaming and Proteins in the Retino-Tectal Neurons of the Pigeon.- Different Modes of Substance Flow in the Optic Tract.- A Symmetrical Double-Label Method for Studying the Rapid Axonal Transport of Radioactivity from Labelled d-Glucosamine in the Gold Fish VisualSystem.- Single Cell Isotope Injection Technique, a Tool for Studying Axonal and Dendritic Transport.- Neuronal Organelles in Neuroplasmic (“Axonal”) Flow, I. Mitochondria.- Neuronal Organelles in Neuroplasmic (“Axonal”) Flow, II. Neurotubules.- Axonal Transport of Proteins in the Optic Nerve and Tract of the Rabbit.- Changes in Microtubules and Neurofilaments in Constricted, Hypoplastic Nerve Fibers.- Effects of Vinblastine and Colchicine on Monoamine Containing Neurons of the Rat, with Special Regard to the Axoplasmic Transport of Amine Granules.- The Importance of Axoplasmic Transport of Amine Granules for the Functions of Adrenergic Neurons.- Axonal Transport of Proteins in the Hypothalamo-Neurohypophysial System of the Rat.- Axonal Transport in the Goldfish Visual System.