About the Book
Metabolomics is the analysis of all metabolites such as metabolic intermediates, hormones and so on, in a given system such as a cell, an organ or a whole organism. It is complementary to the genomics and proteomic analysis of a system and an essential building block towards the understanding of a whole biological system. Being a relatively new approach, a number of techniques have been recently developed in order to experimentally analyse metabolites and many researchers are expanding into this field. Knowledge about the metabolic status of a system is critical for its comprehensive understanding and metobolomics is an important tool for systems biologists. This is the newest title in the successful Molecular Plant Biology Handbook Series. Just like the other titles in the series, The Handbook of Plant Metabolomics presents an excellent overview of different approaches and techniques in the subject. Contributors are either from ivy-league research institutions or from companies developing new technologies in this dynamic and fast-growing field.
With its approach to introduce current techniques in plant metabolomics to a wider audience and with many labs and companies considering to introduce metabolomics for their research, this book is intended for molecular biologists, geneticists, biotechnologists, plant physiologists, gene technologists, protein chemists, biotechnological industry personel and the pharmaceutical industry. With uniform chapter design with summaries and comprehensive glossary, the Kahl books are in addition a trusted brand for the plant science community.
Table of Contents:
Preface CENTRAL METABOLISM Metabolic profiling of plants by GC-MS (Camilla B. Hill, Ute Roessner) Isotopologue profiling: towards a better understanding of metabolic pathways (Wolfgang Eisenreich, Claudia Huber, Erika Kutzner, Nihat Knispel, Nicholas Schramek) Nuclear magnetic resonance spectroscopy for plant metabolite profiling (Sonia van der Sar, Hye Kyong Kim, Axel Meissner, Robert Verpoorte, Young Hae Choi) Comprehensive two-dimensional gas chromatography for metabolomics (Katja Dettmer, Martin F. Almstetter, Christian J. Wachsmuth and Peter J. Oefner) MALDI mass spectrometric imaging of plants (Ales Svatos, Hans-Peter Mock) Medicago truncatula root and shoot Metabolomics: Protocol for the investigation of the primary carbon and nitrogen metabolism based on GC-MS (Vlora Mehmeti, Lena Fragner, Stefanie Wienkoop) SECONDARY AND LIPID METABOLISM Study of the volatile metabolome in plant-insect interactions (Georg J.F. Weingart, Nora C. Lawo, Astrid Forneck, Rudolf Krska, Rainer Schuhmacher) Metabolomics in Herbal Medicine Research (Lie-Fen Shyur, Chiu-Ping Liu, Shih-Chang Chien) Integrative analysis of secondary metabolism and transcript regulation in Arabidopsis Thaliana (Fumio Matsuda, Kazuki Saito) Liquid chromatography mass spectrometry analysis of flavonoids (Maciej Stobiecki, Piotr Kachlicki) GC/MS based lipidomics (Takeshi Furuhashi, Wolfram Weckwerth) Multi-gene transformation for pathway engineering of secondary metabolites (Hideyuki Suzuki, Eiji Takita, Kiyoshi Ohyama, Satoru Sawai, Hikaru Seki, Nozomu Sakurai, Toshiya Muranaka, Masao Ishimoto, Hiroshi Sudo, Kazuki Saito, Daisuke Shibata) METABOLOMICS AND GENOMICS Metabolomics Assisted Plant Breeding (Alexander Herrmann, Nicolas Schauer) Conducting Genome Wide Association Mapping of Metabolites (Susanna Atwell, Daniel J. Kliebenstein) METABOLOMICS AND BIOINFORMATICS Metabolite clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps (Alexander Kaever, Manuel Landesfeind, Kirstin Feussner, Ivo Feussner, Peter Meinicke) Metabolite identification and computational mass spectrometry (Steffen Neumann, Florian Rasche, Sebastian Wolf, Sebastian Bocker) COVAIN - a metabolomics data mining toolbox (Xiaoliang Sun, Wolfram Weckwerth) Mass Spectral Search and Analysis using the Golm Metabolome Database (Jan Hummel, Nadine Strehmel, Christian Bolling, Stefanie Schmidt, Dirk Walther, Joachim Kopka) Glossary Index
