Emerging Areas in Bioengineering: (Advanced Biotechnology)

With more than 40 contributions from expert authors, this is an extensive overview of all important research topics in the field of bioengineering, including metabolic engineering, biotransformations and biomedical applications. Alongside several chapters dealing with biotransformations and biocatalysis, a whole section is devoted to biofuels and the utilization of biomass. Current perspectives on synthetic biology and metabolic engineering approaches are presented, involving such example organisms as Escherichia coli and Corynebacterium glutamicum, while a further section covers topics in biomedical engineering including drug delivery systems and biopharmaceuticals. The book concludes with chapters on computer-aided bioprocess engineering and systems biology. This is a part of the Advanced Biotechnology book series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question. Invaluable reading for biotechnologists and bioengineers, as well as those working in the chemical and pharmaceutical industries. Advanced Biotechnology Biotechnology is a broad, interdisciplinary field of science, combining biological sciences and relevant engineering disciplines, that is becoming increasingly important as it benefits the environment and society as a whole. Recent years have seen substantial advances in all areas of biotechnology, resulting in the emergence of brand new fields. To reflect this progress, Sang-Yup Lee (KAIST, South Korea), Jens Nielsen (Chalmers University, Sweden), and Gregory Stephanopoulos (MIT, USA) have joined forces as the editors of a new Wiley-VCH book series. Advanced Biotechnology will cover all pertinent aspects of the field and each volume will be prepared by eminent scientists who are experts on the topic in question.

Table of Contents:
Contents to Volume 1 List of Contributors xvii About the Series Editors xxxiii Part I Biocatalysis 1 1 Introduction to Emerging Areas in Bioengineering 3 Ho Nam Chang 2 Over-Expression of Functionally Active Inclusion Bodies of Enzymes in Recombinant Escherichia coli 21 Wen-Chien Lee and Shao-Yen Hsu 3 Enzymatic Reactions in Ionic Liquids 35 Ngoc Lan Mai and Yoon-Mo Koo 4 Enzyme Immobilization on Nanoparticles: Recent Applications 67 Cheng-Kang Lee and Ai-Nhan Au-Duong 5 Whole Cell Biocatalysts Using Enzymes Displayed on Yeast Cell Surface 81 Kentaro Inokuma, Tomohisa Hasunuma, and Akihiko Kondo 6 Design of Artificial Supramolecular Protein Assemblies by Enzymatic Bioconjugation for Biocatalytic Reactions 93 Geisa A.L.G. Budinova, Yutaro Mori, and Noriho Kamiya 7 Production of Valuable Phenolic Compounds from Lignin by Biocatalysis: State-of-the-Art Perspective 105 Somchart Maenpuen, Ruchanok Tinikul, Pirom Chenprakhon, and Pimchai Chaiyen Part II Biofuels and Renewable Energy from Biomass 125 8 Biofuels, Bio-Power, and Bio-Products fromSustainable Biomass: Coupling Energy Crops and OrganicWaste with Clean Energy Technologies 127 Serpil Guran, Foster A. Agblevor, and Margaret Brennan-Tonetta 9 Potential Lignocellulosic Biomass Resources in ASEAN Countries 163 Shankar Ramanathan, Madihah Md Salleh, Adibah Yahya, Huszalina Hussin, Wan R.Z.Wan Dagang, Shaza E. Mohamad, Zaharah Ibrahim, Rohaya Mohd Noor, Nursyifaaiyah Abdul Aziz, Zulkefflizan Jamaludin, and Syariffah Nuratiqah Syed Yaacob 10 Volatile Fatty Acid Platform: Concept and Application 173 Nag-Jong Kim, Seong-Jin Lim, and Ho Nam Chang 11 Biological Pretreatment of Lignocellulosic Biomass for Volatile Fatty Acid Production 191 Suraini Abd-Aziz, Mohamad F. Ibrahim, and Mohd A. Jenol 12 Microbial Lipid Production from Volatile Fatty Acids by Oleaginous Yeast 203 Gwon W. Park, Nag-Jong Kim, and Ho Nam Chang 13 Gasification Technologies for Lignocellulosic Biomass 215 Su J. Jeon, Soo H. Jeong, Beom J. Kim, and Uen D. Lee 14 Separation of Butanol, Acetone, and Ethanol 255 Di Cai, Song Hu, Peiyong Qin, and Tianwei Tan 15 Overview of Microalgae-Based Carbon Capture and Utilization 287 Ye Sol Shin, Jaoon Y. H. Kim, and Sang Jun Sim 16 Bioengineering of Microbial Fuel Cells: FromExtracellular Electron Transfer Pathway to Electroactive Biofilm 295 Yang-Yang Yu, Dan-Dan Zhai, and Yang-Chun Yong Part III Synthetic Biology and Metabolic Engineering 305 17 Genome Editing Tools for Escherichia coli and Their Application in Metabolic Engineering and Synthetic Biology 307 Chandran Sathesh-Prabu and Sung K. Lee 18 Synthetic Biology for Corynebacterium glutamicum: An Industrial Host forWhite Biotechnology 321 Han Min Woo 19 Metabolic Engineering of Solventogenic Clostridia for Butanol Production 331 Sang-Hyun Lee and Kyoung Heon Kim 20 Metabolic Engineering of Microorganisms for the Production of Lactate-Containing Polyesters 349 Yokimiko David, Sang Yup Lee, and Si Jae Park 21 MicrobialMetabolic Engineering for Production of Food Ingredients 359 Eun J. Oh, Yong-Su Jin, and Jin-Ho Seo Contents to Volume 2 List of Contributors xix About the Series Editors xxxv Part IV Products 373 22 Application of Lactic Acid Bacteria for Food Biotechnology 375 Ling Li and Nam Soo Han 23 Biopolymers Based on Raw Materials from Biomass 399 Jonggeon Jegal 24 Bacterial Biofertilizers: High Density Cultivation 429 S. Mutturi and Virendra S. Bisaria 25 Current Research in Korean Herbal Cosmetics 441 Jun S. Park, Ga Y. Cho, and Sung-Il Park Part V Biosensing and Nanobiotechnology 463 26 Advanced Genetic Engineering of Microbial Cells for Biosensing Applications 465 Do Hyun Kim, Byung Jo Yu, and Moon II Kim 27 Bioelectronic Nose 477 Hwi Jin Ko, Eun Hae Oh, and Tai Hyun Park 28 Noninvasive Optical Imaging Techniques in Clinical Application 497 Uk Kang and Soo-Jin Bae 29 Advanced Short Tandem Repeat Genotyping for Forensic Human Identification 509 Yong T. Kim, Hyun Y. Heo, and Tae S. Seo 30 DNA Microarray-Based Technologies to Genotype Single Nucleotide Polymorphisms 531 Jung H. Park, Ye L. Jung, Kyungmee Lee, Changyeol Lee, Batule Bhagwan, and Hyun G. Park 31 Advanced Applications of Nanoscale Measuring Systemfor Biosensors 557 Jong M. Kimand Sang-Mok Chang 32 Biosynthesis and Applications of Silver Nanoparticles 579 Bipinchandra K. Salunke and Beom Soo Kim Part VI Biomedical Engineering and Biopharmaceuticals 591 33 Smart Drug Delivery Devices and Implants 593 Ki Su Kim, Ho Sang Jung, Hyunsik Choi, Songeun Beack, Hyemin Kim, Jong Hwan Mun,Myeong Hwan Shin, Do Hee Keum, Heebeom Koo, Seok Hyun Yun, and Sei Kwang Hahn 34 Controlled Delivery Systems of Protein and Peptide Therapeutics 607 Hwiwon Lee,Minsoo Cho, Jeong Ho Lee, Jong HwanMun, ByungWoo Hwang, Hyemin Kim, and Sei Kwang Hahn 35 Cell Delivery Systems Using Biomaterials 617 Youngro Byun and Jee-Heon Jeong 36 Bioengineered Cell-Derived Vesicles as Drug Delivery Carriers 631 Vipul Gujrati and Sangyong Jon 37 Advanced Genetic Fusion Techniques for Improving the Pharmacokinetic Properties of Biologics 645 Seung R. Hwang and JinW. Park 38 Mussel-Mimetic Biomaterials for Tissue Engineering Applications 655 Yun Kee Jo, Hyo Jeong Kim, Eun Yeong Jeon, Bong-Hyuk Choi, and Hyung Joon Cha 39 Mass Production of Full-Length IgG Monoclonal Antibodies from Mammalian, Yeast, and Bacterial Hosts 679 Sang T. Jung and Dong-Il Kim 40 Recent Advances in Mass Spectrometry-Based Proteomic Methods for Discovery of Protein Biomarkers for Complex Human Diseases 697 Sangchul Rho, Hyobin Jeong, Sehyun Chae, Hee-Jung Jung, Sanghyun Ahn, Yun-Hwa Kim, Ju-Young Lee, Soyoung Choi, and Daehee Hwang Part VII Computer-Aided Bioprocess Design and Systems Biology 713 41 Overview on Bioprocess Simulation 715 Shin Je Lee, Dae Shik Kim, JongMin Lee and Chonghun Han 42 Bioprocess Simulation and Scheduling 723 Doug Carmichael, Charles Siletti, Alexandros Koulouris, and Demetri Petrides 43 Metabolism-Combined GrowthModel Construction and Its Application to Optimal Bioreactor Operation 761 Dong H. Jeong, Jung H. Kim, and JongM. Lee 44 Software Applications for Phenotype Analysis and Strain Design of Cellular Systems 771 Meiyappan Lakshmanan, Lokanand Koduru, and Dong-Yup Lee 45 Metabolic Network Modeling for Computer-Aided Design of Microbial Interactions 793 Hyun-Seob Song,William C. Nelson, Joon-Yong Lee, Ronald C. Taylor, Christopher S. Henry, Alexander S. Beliaev, Doraiswami Ramkrishna, and Hans C. Bernstein Index 803

About the Author :
Ho Nam Chang is Professor Emeritus at the Department of Chemical and Biomolecular Engineering at the Korea Advanced Institute of Science and Technology (KAIST). He studied at Seoul National University (South Korea) and received his Master and Ph.D. degrees from Stanford University (USA) in 1971 and 1975. After this time, he returned to Korea and became Professor at KAIST, a position he hold until his retirement in 2010. In 1990, he was elected Director of the Bioprocess Engineering Research Center at KAIST. During his scientific career, Ho Nam Chang became a Humboldt Fellow at the University of Erlangen (Germany, 1980 to 1981), President of the Korean Society for Biotechnology and Bioengineering (1994 to 1995), Member of the Presidential Council on Science and Technology of Korea (1995 to 1997) and Honorary Professor at Nanjng University of Technology (China). Jens Nielsen has a PhD degree (1989) in Biochemical Engineering from the Danish Technical University (DTU), and after that established his independent research group and was appointed full Professor there in 1998. He was Fulbright visiting professor at MIT in 1995-1996. At DTU he founded and directed the Center for Microbial Biotechnology. In 2008 he was recruited as Professor and Director to Chalmers University of Technology, Sweden. Jens Nielsen has received numerous Danish and international awards including the Nature Mentor Award, and is member of several academies, including the National Academy of Engineering in USA and the Royal Swedish Academy of Science. He is a founding president of the International Metabolic Engineering Society. Professor Gregory Stephanopoulos is the W. H. Dow Professor of Chemical Engineering at the Massachusetts Institute of Technology (MIT, USA) and Director of the MIT Metabolic Engineering Laboratory. He is also Instructor of Bioengineering at Harvard Medical School (since 1997). He has been recognized by numerous awards from the American Institute of Chemical Engineers (AIChE) (Wilhelm, Walker and Founders awards), American Chemical Society (ACS), Society of industrial Microbiology (SIM), BIO (Washington Carver Award), the John Fritz Medal of the American Association of Engineering Societies, and others. In 2003 he was elected member of the National Academy of Engineering (USA) and in 2014 President of AIChE.