Peroxide Chemistry: Mechanistic and Preparative Aspects of Oxygen Transfer Research Report(Forschungsberichte (DFG))

This collection of thirty articles on research projects in all areas of peroxide chemistry, i. e. analytical, biochemical, inorganic, organic, organometallic, physical, spectroscopic, and theoretical facets, are the result of a multidisciplinary research program funded by the Deutsche Forschungsgemeinschaft (DFG). The emphasis was to lie on the development of environmentally acceptable, selective (chemo--, regio--, diastereo-- and enantioselectivity) oxidations. One chapter focuses on industrial applications which have to meet both economical and ecological demands to remain competitive in the future. Latest results on the consequences of lipid peroxidation in age--dependent diseases, which range from Alzheimer and Parkinson disorders to diabetes, rheumatic arthritis, atherosclerosis and cardiovascular diseases are also presented.

Table of Contents:
Preface. HISTORICAL MEMENTOS. Landmarks in the Development of Organic Peroxide Chemistry (M. Schulz). OXIDATION WITH ORGANIC PEROXIDES. Recent Advances in Homogeneous Catalyzed Epoxidations Using Hydrogen Peroxide or tert.--Butyl Hydroperoxide (T. Kratz & W. Zeibeta). Photoinduced Electron--Transfer Reactions of Alkenes and Azide Anions in the Presence of Molecular Oxygen: Formation of 1,2--Azidohydroperoxides and Use as Oxygen--Transfer Reagents (A. Griesbeck, et al.). Preparative Use of Peroxidic Oxidants for Oxygen--Transfer Reactions (W. Adam, et al.). Organosulfonic and Sulfonimidic Peracids -- New Oxidants for Diastereoselective and Enantioselective Oxidations of Organic Substrates (M. Schulz & R. Kluge). Reactive Peroxo Compounds Generated in Situ from Hydrogen Peroxide: Kinetics and Catalytic Application in Oxidation Processes (H. Elias & S. Vayssie). Carbonyl O--Oxides and Dioxiranes -- From Laboratory Curiosities to Useful Reagents (K. Block, et al.). Formation of Dioxiranes and Singlet Molecular Oxygen by the Ketone--Catalyzed Decomposition of Peroxycarboxylic Acids (A. Lange & H.--D. Brauer). ENZYMATIC AND BIOMIMETIC OXIDATIONS. Age and Age--Dependent Diseases, a Consequence of Lipid Peroxidation (G. Spiteller, et al.). New Peroxycarboxylic Acids by Lipase Catalysis: Preparation and Oxidation Properties (S. Warwel M. Klaas). Transition--Metal--Catalyzed Oxyfunctionalization of Catechol and Flavonol Derivatives (F. Schweppe, et al.). Binding and Activation of Dioxygen by Biomimetic Metal Complexes (E. Jager, et al.). Transition Metal--Catalyzed Stereoselective Synthesis of Functionalized Tetrahydrofurans (S. Drees, et al.). METAL--CATALYZED SELECTIVE OXIDATIONS. Metallosalen--Catalyzed Asymmetric Oxygen--Transfer Reaction: Dynamics of Salen Ligand Conformation (T. Katsuki). Transition--Metal Catalyzed Epoxidation of Unfunctionalized Alkenes (A. Scheurer, et al.). Peroxo Complexes of Molybdenum, Tungsten and Rhenium with Phase Transfer Active Ligands: Catalysts for the Oxidation of Olefins and Aromatics by Hydrogen Peroxide and Bistrimethylsilyl Peroxide (C. Jost, et al.). Kinetic Resolution by Jacobsen Epoxidation as an Easy Route to Podophyllotoxin Analoga (T. Linker, et al.). Preparation of Optically Active Hydroperoxides and their Use for Stereoselective Oxygen Transfer (H.--J. Hamann, et al.). New Early Transition--Metal Complexes as Homogeneous Catalysts for Olefin Oxidation (W. Herrmann, et al.). Olefin Epoxidation Catalyzed by Molybdenum Peroxo Complexes: A Mechanistic Study (W. Thiel, et al.). Oxidation Reactions in Perfluorinated Solvents (B. Betzemeier & P. Knochel). Transition--Metal Alkoxide--Catalyzed Oxidation of Phenols Alcohols, and Amines with tert.--Butyl Hydroperoxide (H. Adam, et al.). Enantioselective Baeyer--Villiger Reactions and Sulfide Oxidations (C. Bolm). Chiral Pentacoordinated Manganese Complexes as Biomimetic Catalysts for Asymmetric Epoxidations with Hydrogen Peroxide (A. Berkessel, et al.). Photocatalytic Activation of Oxygen by Iron(III)porphyrins (H. Hennig & D. Luppa). Oxidation and Oxygenation of Substituted Arenes with Alkyl Hydroperoxides or Dioxygen/Mediation by Schiff--Base Complexes (A. Rieker, et al.). SPECTROSCOPY -- THEORY. The Nature of the Transition Structures for Oxygen Atom Transfer from Peroxy Acids, Dioxiranes and Chiral Bis(silyl) Peroxides (R. Bach). Mechanistic Aspects of Transition--Metal--Catalyzed Olefin Epoxidation from Density Functional Studies (N. Rosch, et al.). Near--UV Photolysis of Singlet Oxygen Generated by Energy Transfer from Aromatic Molecules in Rare--Gas Matrices (M. Gudipati, et al.). Transition--Metal Ion Chemistry of Peroxides in the Gas Phase (D. Schroder, et al.).