Interventional Oncology: A Multidisciplinary Approach to Image-Guided Cancer Therapy

This book is an up-to-date and comprehensive guide to interventional oncology (IO). Imaging and screening allows early detection of cancer when tumors are still small and confined. Imaging also allows for accurate guidance of needles, probes, antennae, lasers, and cancers to sites of cancers for minimally invasive and effective treatment. IO is practiced by radiologists, surgeons, pulmonologists, and gastroenterologist to improve, cure, and minimize morbidity for patients. Increasingly, IO procedures are also used for palliation by treating infection or by alleviating pain or organ obstruction. The growth in this field has been greatly aided by technological improvements in ablative tools, imaging, and image-guided navigation. Practitioners of IO are a large workforce in most modern hospitals, responsible for a large number of patients daily. Understanding concepts underlying IO procedures, as well as devices and procedures available, is essential for all who participate in the care of the cancer patient. This book is a state-of-the-art overview of IO and is authored by the scientists and clinicians who have pioneered the field. Overall, it summarizes the history, current technology, common procedures, and future prospects in the field.  It includes procedures from many surgical and interventional radiologic disciplines because 1) it aims to be definitive, and 2) often procedures are performed partly in interventional radiology and partly in the surgical suite. This new edition includes 20 new chapters and delves deeper into specific treatment methods and practice guidelines. The book is separated into three main sections with multiple parts. In the first, the history and technical principles that underlie tumor ablation are presented. The second part discusses current imaging modalities used for guidance of these procedures and monitoring of their effectiveness. Included in this section are considerations of workflow, OR/IR architecture, and financial issues revolving around IO.  The book then moves on to organ-specific applications of IO, including 1) primary liver cancer, 2) metastatic tumors to the liver, 3) lung tumors, 4) renal tumors, 5) prostate tumors, 6) bone tumors, and 7) miscellaneous tumors. The currently available equipment and equipment anticipated in the near future, special populations, and illustrations of the most common procedures are also included. This book is intended to summarize the field for surgeons and interventional radiologists at all levels. This field being highly collaborative, the authors of chapters in this book are from many disciplines, making this a definitive text on the theory and practice of IO relevant to all clinicians interested in cancer therapy.

Table of Contents:
Part I: Interventional Oncology: Science, Technology, and Theory.- Tumor Ablation: An Evolving Technology.- Electroporation.- Microwave Ablation.- CryoAblation.- HIFU.- Embolic Therapy.- Radiation Therapy: IMRT, Cyberknife, Gamma Knife, Proton Beam.- ChemoAblation (PIPAC).- Laser Ablations.- Emerging Technologies.- Part II: Developing and Sustaining an Interventional Oncology Program.- Designing Rooms for Image-Guided Therapy.- Financial Considerations.- Anesthesia Management.- Post procedure pain management.- Patient Management and workflow.- Devices, Equipment and their Operation.- Part III: Imaging of Interventional Therapies.- Ultrasound.- CT.- MRI.- PET/CT.- Fluoroscopy and Flat panel C-arms.- Image Guidance, Robotics, and Fusion Systems.- Thermography.- Part IV: Organ Based Interventions: Primary Liver.- Overview of IO for Primary Liver Cancer.- Percutaneous RF.- Microwave.- Electroporation.- HIFU.- Laser: LITT.- Cryoablation.- PEI: Injectables.- Particle and Chemoembolization.- Radioembolization for Primary Liver Cancer.- Combination Therapies.- Radiation Therapy.- Part V: Organ Based Interventions: METS to Liver.- Overview of IO for Metastatic Liver Cancer.- Percutaneous Ablation.- Embolic Therapy.- Radioembolization for Metastatic Liver Cancer.- Electroporation.- Intraoperative Surgery.- Radiation Therapy.- Radioimmunotherapy for Neuroendocrine Tumors.- Adjuvant Chemotherapy after Ablation.- Part VI: Organ Based Interventions: Lung.- Overview of IO for Lung Tumors.- Percutaneous IR.- Combination Therapies.- Resection Incl Minivas.- Radiation Therapy.- Transbronchial Ablation.- Chemotherapy and Immunotherapy Adjuvants to Ablation.- Part VII: Organ Based Interventions: Bone.- Overview of IO for Bone Metastases.- RF Perc.- Cryoablation.- Radiation Therapy.- Part VIII: Organ Based Interventions: Renal Cell.- Overview of IO for Renal Cell Carcinoma.- RF-Perc.- Cryoablation.- Radiation Oncology.- Robotic and other MIS Approaches.- Chemotherapy and targeted therapies, biological.- Part IX: Organ Based Interventions: Prostate.- Overview of IO for Prostate Cancer.- RF-Perc.- Cryoablation.- HIFU.- Surgical Approach for Prostate Cancer.- Radiation Oncology.- Part X: Organ Based Interventions: Gynecology Applications.- Overview of IO for Gyn Tumors.- Ablation.- Embolic Therapy.- HIFU.- Radiation Oncology.- Surgical and intraoperative Ablation.- Medical Oncology.- Part XI: Organ Based Interventions: Breast.- RF/Microwave/Cryotherapy for Breast Tumors.- Intraoperative radiation.- Part XII: Palliative Procedures for Cancer Patients.- Interventional palliation for pain related to cancer.- MIS Surgery and palliation for pain.- Palliation for obstruction and malnutrition.- Part VI. Special Populations and Considerations.- Interventional Therapy for Children.- Pacemakers and other electronic challenges.- Percutaneous pain management.- Endoscopic pain management.

About the Author :
Yuman Fong, MD, FACS is the Sangiacomo Chair in Surgery, Professor, and Chairman of the Department of Surgery at the City of Hope Medical Center in Duarte, CA. Anne Covey, MD is an Interventional Radiologist at Memorial Sloan Kettering Cancer Center. Muneeb Ahmed, MD is Associate Professor of Radiology at Harvard Medical School. John Kessler, MD is an Interventional Oncologist and Assistant Professor at City of Hope Medical Center in Duarte, CA. David A. Iannitti, MD is Chief of Hepatopancreaticobiliary Surgery at Carolinas Medical Center in Charlotte, NC. Damian Dupuy, MD is Director of Tumor Ablation at Cape Cod Hospital in Hyannis, MA.