Stem Cell Bioprocessing
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Home > Medicine & Health Science textbooks > Nursing and ancillary services > Biomedical engineering > Stem Cell Bioprocessing: For Cellular Therapy, Diagnostics and Drug Development(40 Woodhead Publishing Series in Biomedicine)
Stem Cell Bioprocessing: For Cellular Therapy, Diagnostics and Drug Development(40 Woodhead Publishing Series in Biomedicine)

Stem Cell Bioprocessing: For Cellular Therapy, Diagnostics and Drug Development(40 Woodhead Publishing Series in Biomedicine)


     0     
5
4
3
2
1



Out of Stock


Notify me when this book is in stock
X
About the Book

Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion and/or differentiation. Stem cell separation techniques are also discussed, aiming towards both isolation and purification of rare stem cell populations. For a better understanding of these processes, basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent and promising induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Novel approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules and the use of microfluidic devices for both stem cell culture and separation. A further section is dedicated to application of stem cells for regenerative medicine including on-going clinical trials.

Table of Contents:
Stem cells; Stem cell culture; Bioreactors for stem cell culture; Stem cell bioseparation; Micro-scale technologies for stem cell culture and separation; Stem cells and regenerative medicine.

About the Author :
Dr. Tiago G. Fernandes is currently a Post-doctoral research fellow at the Institute for Biotechnology and Bioengineering, Lisbon, Portugal. His research interests are focused on the development of artificial cellular niches for studying the mechanisms that affect human stem cell pluripotency, and aim at contributing to a better understanding of the cellular and molecular events that regulate stem cell functions. During his doctoral studies he also worked at the Rensselaer Polytechnic Institute, NY, USA, in the development of microscale platforms for high-throughput studies of stem cell fate. His work has earned him the prestigious Malcolm Lilly award, presented to a promising young scientist or engineer working in the biochemical engineering field, at the 7th European Symposium on Biochemical Engineering Science (2008). Dr. Fernandes is currently involved in several research projects financed by the Portuguese Foundation for Science and Technology (FCT), as well as by the European Community, related to the development of different systems for pluripotent stem cell culture envisaging further applications in regenerative medicine and drug screening. Dr. Maria Margarida Diogo received her PhD degree in Biotechnology from Instituto Superior Tecnico from January 2000 to April 2004. Her thesis was dedicated to the development of Bioprocesses for Production and Purification of Plasmid DNA for Gene Therapy and DNA vaccines. As a result of this work, a United States Patent was published in 2007. From April 2004 to March 2008 she received a post-doctoral fellowship to work in the field of Stem Cell Bioengineering and she is presently a Research Scientist at the Stem Cell Bioengineering Laboratory at Instituto Superior Tecnico. She is involved in several research projects financed by the Portuguese Foundation for Science and Technology (FCT) as well as by the European Community related to development of large-scale bioprocessing strategies for human Induced Pluripotent and Neural Stem Cell culture and purification envisaging further applications in regenerative medicine and drug screening. As a complementary approach, she is the Principal Investigator of a project for development of microscale technologies for stem cell culture. Dr. Joaquim M. S. Cabral is Professor of Biological Engineering, in the Department of Bioengineering at Instituto Superior Tecnico (IST), Technical University of Lisbon, Portugal. He was the founder and current Head of Department of Bioengineering, and the Director of the Institute for Biotechnology and Bioengineering, a Research Laboratory Associated to the Ministry of Science, Technology and Higher Education in Portugal. He obtained his Diploma in Chemical Engineering from IST in 1976. His Ph.D. and 'Habilitation' degrees in Biochemical Engineering were obtained from IST in 1982 and 1988, respectively. After a post-doctoral study at Massachusetts Institute of Technology in 1983-1984, he joined IST Faculty as Assistant Professor and became a Full Professor in 1992. Joaquim Cabral's research aims at contributing for biochemical engineering science through novel developments in Bioprocess Engineering and Stem Cell Bioengineering. Stem Cell Bioengineering interests address the ex-vivo expansion and controlled differentiation of stem cells in bioreactor systems, using Hematopoietic stem cells (HSC), mesenchymal stem cells (MSC) and embryonic stem cells (ESC) as model systems. He is member of several Editorial Boards of scientific journals and of Organizing and Scientific Committees of conferences in the areas of Biotechnology and Stem Cells, Tissue Engineering and Regenerative Medicine. He has published over 370 research papers and co-authored or edited six books. He was member of the Section on Applied Biocatalysis of European Federation of Biotechnology (EFB), since 1986 until 2005 and Chairman of this Section from 1991 until 1996. In 2005, he was nominated Honorary Member. He was also member of Executive Committee of the EFB Section on Biochemical Engineering Science from 1999 until 2004. He serves as a member of several Advisory Boards including the Biotechnology Strategy Group of the European Academies' Science Advisory Council (EASAC), The Royal Society (2002-2005), the Expert Panel of the Engineering and Physical Sciences Research Council, UK (2006-2012), the Expert Panel of Biotechnology and Biological Sciences Research Council, UK (1995-2005), the International Peer Review Committee of the B-Basic Program, Advanced Chemical Technologies for Sustainability, NOW, The Netherlands, (2004 -2007) and currently is the President of the Exact Sciences and Engineering Scientific Council of the Portuguese Foundation for Science and Technology (since 2009).


Best Sellers


Product Details
  • ISBN-13: 9781908818300
  • Publisher: Elsevier Science & Technology
  • Publisher Imprint: Woodhead Publishing Ltd
  • Series Title: 40 Woodhead Publishing Series in Biomedicine
  • ISBN-10: 1908818301
  • Publisher Date: 31 Oct 2013
  • Binding: Digital (delivered electronically)
  • Sub Title: For Cellular Therapy, Diagnostics and Drug Development


Similar Products

Add Photo
Add Photo

Customer Reviews

REVIEWS      0     
Click Here To Be The First to Review this Product
Stem Cell Bioprocessing: For Cellular Therapy, Diagnostics and Drug Development(40 Woodhead Publishing Series in Biomedicine)
Elsevier Science & Technology -
Stem Cell Bioprocessing: For Cellular Therapy, Diagnostics and Drug Development(40 Woodhead Publishing Series in Biomedicine)
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Stem Cell Bioprocessing: For Cellular Therapy, Diagnostics and Drug Development(40 Woodhead Publishing Series in Biomedicine)

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept

    Fresh on the Shelf


    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!