Biosensors for Medical Applications
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Biosensors for Medical Applications: (Woodhead Publishing Series in Biomaterials)

Biosensors for Medical Applications: (Woodhead Publishing Series in Biomaterials)


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About the Book

Biomedical sensors are an essential tool in the detection and monitoring of a wide range of medical conditions from cancer to Parkinson’s disease. Biosensors for medical applications provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications.Part one focuses on key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors. Impedence interrogated affinity biosensors for medical applications and practical applications of enzyme biosensors are explored, before part two goes on to review specific medical applications. Biosensors for DNA and RNA detection and characterization, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors are investigated, along with biosensors for drug testing and discovery, non-invasive measurements, and wearable biosensors for medical applications.With its distinguished editor and international team of expert contributors, Biosensors for medical applications is an essential guide for all those involved in the research, design, production and use of medical biosensors.

Table of Contents:
Contributor contact details Woodhead Publishing Series in Biomaterials Introduction to biosensors Part I: Principles and transduction approaches Chapter 1: Electrochemical biosensors for medical applications Abstract: 1.1 Introduction to electrochemical sensors 1.2 Electrochemical biosensing applications 1.3 Label-free approaches to electrochemical sensors 1.4 Conclusion and future trends Chapter 2: Piezoelectric biosensors for medical applications Abstract: 2.1 Introduction 2.2 Piezoelectric immunosensors 2.3 Piezoelectric genosensors 2.4 Piezoelectric biosensors with bio-mimetic receptors 2.5 Conclusions and future trends Chapter 3: Nano-sized biosensors for medical applications Abstract: 3.1 Introduction 3.2 Sensing modalities 3.3 Nanomaterial properties 3.4 Biosensors on the nanoscale 3.5 Conclusions Chapter 4: Impedance interrogated affinity biosensors for medical applications: novel targets and mechanistic studies Abstract: 4.1 Small molecule binding 4.2 Supramolecular structures 4.3 Electrochemical biosensor for clinical diagnostics 4.4 Challenges of carbohydrate sensing 4.5 Bioreceptors for carbohydrate sensing 4.6 Enzymes that act on carbohydrates 4.7 Impedimetric glucose biosensors 4.8 Impedimetric bacterial and viral immunosensors 4.9 Impedance and pathogens 4.10 Bioreceptors used in impedimetric pathogenic biosensor construction 4.11 Detection of exposure to infection 4.12 Conclusion Chapter 5: Practical applications and protocols for enzyme biosensors Abstract: 5.1 Introduction 5.2 Methods and approaches for using biosensors 5.3 Protocols for enzyme biosensors Method 5.4 Problems arising from the construction and use of biosensors Part II: Applications of medical biosensors Chapter 6: Biosensors for DNA and RNA detection and characterization Abstract: 6.1 Introduction to nucleic acids and base pairing 6.2 Principles of DNA/RNA sensing 6.3 Electrochemical DNA sensing 6.4 Optical DNA sensing 6.5 Quartz crystal microbalance and surface acoustic wave sensors 6.6 Microcantilever oligonucleotide sensors 6.7 Conclusions Chapter 7: Biosensors for disease biomarker detection Abstract: 7.1 Introduction 7.2 Disease biomarkers 7.3 Established technologies for disease biomarker detection 7.4 Proteins at surfaces 7.5 Emerging technologies for disease biomarker detection 7.6 Future trends 7.7 Sources of further information and advice Chapter 8: Affibodies as an alternative to antibodies in biosensors for cancer markers Abstract: 8.1 Introduction: cancer 8.2 Breast cancer 8.3 Human epidermal growth factor receptor 2 (HER2) 8.4 The immunoassay 8.5 Biosensors 8.6 Problems with antibodies 8.7 Affibodies Chapter 9: Biosensors for drug testing and discovery Abstract: 9.1 Introduction 9.2 Types of biosensor 9.3 Conclusion 9.4 Acknowledgements Chapter 10: Biosensors for non-invasive measurements Abstract: 10.1 Introduction 10.2 Biosensors for the detection of alcohol and lactate 10.3 Detection using electrochemical and amperometric biosensors 10.4 Detection using optical biosensors 10.5 Conclusions Chapter 11: Wearable biosensors for medical applications Abstract: 11.1 Introduction 11.2 Background 11.3 Considerations and requirements for wearable sensors 11.4 Types of wearable sensors 11.5 Temperature sensors 11.6 Mechanical sensors 11.7 Electrical sensors 11.8 Biological and chemical sensing 11.9 Clinical applications 11.10 Future trends 11.11 Sources of further information and advice Index

About the Author :
Seamus Higson is Professor of Bio- and Electro-analysis and Commercial Director of Cranfield Health at Cranfield University, UK. A member of the UK Engineering and Physical Sciences Research Council (EPSRC), Professor Higson serves in an advisory and/or consultative capacity for a number of public bodies, and has written extensively on a wide range of topics within the fields of medicine, biotechnology, materials science and health.


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Product Details
  • ISBN-13: 9781845699352
  • Publisher: Elsevier Science & Technology
  • Publisher Imprint: Woodhead Publishing Ltd
  • Height: 234 mm
  • No of Pages: 360
  • Weight: 690 gr
  • ISBN-10: 1845699351
  • Publisher Date: 21 Aug 2012
  • Binding: Hardback
  • Language: English
  • Series Title: Woodhead Publishing Series in Biomaterials
  • Width: 156 mm


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Biosensors for Medical Applications: (Woodhead Publishing Series in Biomaterials)
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