About the Book
Updated and expanded, Textbook of Assisted Reproductive Techniques, Second Edition, Laboratory and Clinical Perspectives provides a authoritative manual for the entire IVF team. There are many books on IVF procedure, but none have combined the laboratory and clinical aspects to cover the subject so comprehensively. The book brings together leading medical and scientific experts to describe, in a clear and concise manner, the hows, whys, and reasoning behind ART.
The laboratory procedures section provides step-by-step how-tos for setting up the ART laboratory, covering everything that has to do with surroundings, equipment, conditions, quality control, and accreditation for the laboratory. The clinical techniques section discusses patient care from investigation to management to complications. New chapters cover: stem cells, genetic analysis, the role of the nurse, stress and outcomes, management of hydrosalpinx, prognostic assessment of ovarian reserve, quality management, setting up a national registry, health economic aspects, fertility preservation strategies, vitrification of oocytes, and more.
One of the things that makes this book so special is its contributors, all of whom are world leaders in the field and experts in their specific topic. The information is presented in a highly visual manner, making methods and protocols easy to find and understand. The book gives research fellows insight into technical developments, provides clinical and scientific teams with the A to Zs of setting up an embryology laboratory, and supplies seasoned professionals with a review of the newest techniques and advances.
Table of Contents:
Preface
Introduction: the beginnings of human in vitro fertilization, Robert G Edwards
LABORATORY PROCEDURES
Setting up an IVF Laboratory
Setting up an ART laboratory, Jacques Cohen, Antonia Gilligan, and John Garrisi
Quality control: maintaining stability in the laboratory, David H McCulloh
Accreditation of the ART laboratory: the North American perspective, Brooks A Keel and Tammie K Schalue
Accreditation of the ART laboratory: the European perspective, Cecilia Sjöblom
Handling and Preparation of the Sperm and Oocytes
Evaluation of sperm, Kaylen M Silverberg and Tom Turner
Sperm preparation techniques, Harold Bourne, David H Edgar, and HW Gordon Baker
Sperm chromatin assessment, Ashok Agarwal and Tamer M Said
Oocyte treatment: from retrieval to insemination, Thomas B Pool and Virginia A Ord
Preparation and evaluation of oocytes for intracytoplasmic sperm injection, Irit Granot and Nava Dekel
Oocyte in vitro maturation, Johan Smitz, Daniela Nogueira, Leen Vanhoutte, Daniel Gustavo de Matos, and Rita N Cortvrindt
Micromanipulation
Equipment and general technical aspects for micromanipulation of gametes and embryos, Frank L Barnes
Intracytoplasmic sperm injection: technical aspects, Gianpiero D Palermo, Queenie V Neri, Takumi Takeuchi, Lucinda Veeck, and Zev Rosenwaks
Assisted hatching, Anna Veiga, Irene Boiso, and Itziar Belil
Human embryo biopsy for preimplantation genetic diagnosis, Alan H Handyside
Culture of the Embryo and Embryo Transfer
Analysis of fertilization, Lynette A Scott
Culture systems for the human embryo, David K Gardner and Michelle Lane
Evaluation of embryo quality: sequential analysis of embryo development with the aim of single embryo transfer, Denny Sakkas and David K Gardner
Cryopreservation of Gametes and Embryos
Slow freezing of human oocytes, Eleonora Porcu
Vitrification of human oocytes, Kwang-Yul Cha, Tae-Ki Yoon, Thomas Kim, and Hyung-Min Chung
Slow freezing of human embryos, Lucinda L Veeck, Rosemary Berrios, Richard Bodine, Robert N Clarke, and Nikica Zaninovic
Vitrification of human embryos, Tetsunori Mukaida and Magosaburo Kasai
Managing the cryopreserved embryo bank, Phillip Matson, Denise Mehmet and Tinka Mehta
Cryopreservation and storage of spermatozoa, Eileen A McLaughlin
Handling and cryopreservation of testicular sperm, Weber W Chuang, William W Lin, Benjamin Hendin, Dolores J Lamb, and Larry I Lipshultz
Ovarian tissue cryopreservation and other fertility preservation strategies, Ozgur Oktem, Murat Sonmezer, and Kutluk Oktay
Diagnosis of Genetic Disease in Preimplantation Embryos
Preimplantation genetic diagnosis using comparative genomic hybridization, Leeanda Wilton and Lucille Voullaire
Severe male factor: genetic consequences and recommendations for genetic testing, Inge Liebaers, André Van Steirteghem, and Willy Lissens
Chromosomal abnormalities in human embryos, Santiago Munné, Mireia Sandalinas, Mina Alikani, and Jacques Cohen
Genetic analysis of the embryo, Yural Yaron, Ronni Gamzu, and Mira Malcov
Polar body biopsy, Markus Montag, Katrin van der Ven, and Hans van der Ven
Clinical application of polar body biopsy, Yury Verlinsky and Anver Kuliev
Implantation
Embryonic regulation in the implantation process, Francisco Domínguez, Antonio Pellicer, and Carlos Simón
The use of biomarkers for the assessment of uterine receptivity, Jeremy M Groll and Bruce A Lessey
Data Management and Interpretation
Setting up an ART national registry, Karl G Nygren
Evidence-based medicine: issues in evaluating efficacy of treatment in assisted reproduction, Salim Daya
Health economics of ART, John Collins
CLINICAL TECHNIQUES
Quality Management Systems
Quality management in reproductive medicine, Christoph Keck, Robert Fischer, and Vera Baukloh, Michael Alper
Patient Investigation and the Use of Drugs
Indications for IVF treatment: from diagnosis to prognosis, Nicholas S Macklon, and Bart CJM Fauser
Initial investigation of the patient (female and male), Bulent Gulekli, Tim J Child, and Seang Lin Tan
Drugs use for controlled ovarian stimulation: clomiphene citrate, aromatase inhibitors, gonadotropins, and gonadotropin-releasing hormone analogs, Zeev Shoham
The role of FSH and LH in ovulation induction: current concepts and the contribution of recombinant gonadotropins, Juan Balasch
Developing new therapeutics for ART: recombinant DNA technology and beyond, Colin M Howles and Steve Arkinstall
Stimulation Protocols
Endocrine characteristics of ART cycles, Jean-Noël Hugues and Isabelle Cédrin-Durnerin
The use of GnRH agonists, Judith AF Huirne and Roel Schats
GnRH antagonists, Michael Ludwig
Monitoring IVF cycles, Matts Wikland and Torbjörn Hillensjö
Follicle aspiration, Carl Wood
Review :
"will guide, assist, and provide foundation and reference to both the neophyte and the seasoned ARTisan." --Fertility and Sterility "The book's real value is that we discuss a day-to-day problem in the unit and know immediately where to look." --Orgyn "anything you may want to look up or simply browse through, you will find in this very comprehensive and competent volume." --ObGyn.net Promo Copy
