About the Book
Diabetes mellitus is known to be a chronic metabolic disorder caused due to an impaired metabolism of glucose and other energy-providing molecules characterized by a slow progression of vascular and neuropathic complications. The present volume reviews the elucidation of several bioactive extracts from 25 potential medicinal plants (largely used in traditional medicine) and their mechanism of action in treatment of diabetes. These 25 herbs have been proved for its anti-diabetic potential using in vitro and in vivo model systems. Several strategies have been used in the management and treatment of diabetes. These strategies are targeted towards increasing endogenous insulin availability (sulfonylureas) enhancing insulin sensitivity and inhibiting ?-glucosidase. Experimental evidences presented in core drug have shown and proven that each of these herbs possess bioactive compounds with anti-diabetic properties. In other words, this volume is a comprehensive compilation covering all aspects of Diabetes Management touching from topics like Definition and Etiology, Pathophysiology to adversities and toxicology, from pharmacological management to herbal drug delivery through Nanotechnology, from insights into the plant insulin to insights into the management of metabolic disorders in pharmacology. Hence, the information is presented in two parts. Diabetes I provide information on the wide range of basic components that are necessary for the management of Diabetes. Besides, the review of seven plants namely, Adhatoda vasica, Aegle marmelos, Andrographis paniculata, Allium sativum, Annona squamosa, Azadirachta indica and Carissa edulis, serves as a compilation of details in the isolation of pure compounds in relation to antidiabetic effects and their potential mode of action. In the second part i.e. Diabetes II, eighteen plants presented are Cinnamon, Coccinia indica, Eucalyptus globulus, Eugenia jambos, Ficus glomerata, Gymnema sylvestris, Ipomea batotos, Medicago sativa, Momordica charantia, Nelumbo nucifera, Nigella sativa, Pongamia pinnata, Swertia chirayita, Syzygium malaccense, Tinospora cordifolia, Trigonella foenum-graceum, Vinca rosea, Withania somnifera. Both the volumes have been presented in a manner that is simple and easy to understand where a balance between theory and practical inputs has been struck. The contributions are from far and wide including Canada, Ethiopia India, KSA, Malaysia, Mauritius, Nigeria, Pakistan, Romania, Spain, and USA. The volume is aimed at a wide range of audience of ethno botanists, phytochemists, pharmacologists, pharmacists, pharmacognosists and other research scientists engaged in the search of new drugs from natural resources for Diabetes Mellitus treatment.
About the Author :
J.N. Govil (B. 1945): Obtained his Master's and Doctorate degrees from Agra University, Agra, India. In his career span of 41 years research experience at the Indian Agricultural Research Institute, New Delhi, Dr. Govil has been involved in the breeding of cross-pollinated, often cross-pollinated, and self-pollinated crops. His research was mainly focused on breeding for better quality, disease resistance, and for higher productivity in Pennisetum, Sorghum, maize, chickpea, and pigeonpea. During these years at IARI, he has released nine varieties of early pigeonpea in arhar-wheat rotation. Dr. Govil has been well exposed to the international scientific community through various programmes at UK, Denmark and Thailand. He also participated in various international seminars and conferences. Dr. Govil is credited with more than ninety research papers in various journals of national and international repute in various aspects of genetics, crop breeding, and topics on general agriculture. He has also guided more than a dozen post-graduate students. Dr. Govil is recipient of no. of Awards and Honor presented by ICAR and Agricultural Societies. He has written and edited a number of books on Medicinal Plants and other books with international authors. A new series "Recent Progress in Medicinal Plants" has been published by Studium Press, LLC, USA in 44 volumes under Dr. Govil's Chief Editorship. Dr. Govil has been the main resource person as Executive Editor in Execution, Co-ordination and Completion of Projects in bringing 12 Vols Set each on Nanotechnology, Biotechnology, Energy Science and Technology, and Environmental Science and Engineering. Simultaneously, Dr. Govil has brought four volumes set of Chemical Technology Series comprising 2 vols each on Advances in Fertilizer Technology as well as on Petroleum Engineering under the capacity of Acquisition Editor of the Series. Dr. Govil retired from ICAR service during the year 2007. Presently, he is working as Publishing Director and Managing Editor with Studium Press LLC, USA (Camped at New Delhi, India) and has brought out nearly 310 scientific books publication during last eight years. E-mail: jngovil@gmail.com; jngovil@hotmail.com
J.N. Govil (B. 1945): Obtained his Master's and Doctorate degrees from Agra University, Agra, India. In his career span of 41 years research experience at the Indian Agricultural Research Institute, New Delhi, Dr. Govil has been involved in the breeding of cross-pollinated, often cross-pollinated, and self-pollinated crops. His research was mainly focused on breeding for better quality, disease resistance, and for higher productivity in Pennisetum, Sorghum, maize, chickpea, and pigeonpea. During these years at IARI, he has released nine varieties of early pigeonpea in arhar-wheat rotation. Dr. Govil has been well exposed to the international scientific community through various programmes at UK, Denmark and Thailand. He also participated in various international seminars and conferences. Dr. Govil is credited with more than ninety research papers in various journals of national and international repute in various aspects of genetics, crop breeding, and topics on general agriculture. He has also guided more than a dozen post-graduate students. Dr. Govil is recipient of no. of Awards and Honor presented by ICAR and Agricultural Societies. He has written and edited a number of books on Medicinal Plants and other books with international authors. A new series "Recent Progress in Medicinal Plants" has been published by Studium Press, LLC, USA in 44 volumes under Dr. Govil's Chief Editorship. Dr. Govil has been the main resource person as Executive Editor in Execution, Co-ordination and Completion of Projects in bringing 12 Vols Set each on Nanotechnology, Biotechnology, Energy Science and Technology, and Environmental Science and Engineering. Simultaneously, Dr. Govil has brought four volumes set of Chemical Technology Series comprising 2 vols each on Advances in Fertilizer Technology as well as on Petroleum Engineering under the capacity of Acquisition Editor of the Series. Dr. Govil retired from ICAR service during the year 2007. Presently, he is working as Publishing Director and Managing Editor with Studium
Press LLC, USA (Camped at New Delhi, India) and has brought out nearly 310 scientific books publication during last eight years. E-mail: jngovil@gmail.com; jngovil@hotmail.com
