COPD is / is Not a Systemic Disease?
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COPD is / is Not a Systemic Disease?

COPD is / is Not a Systemic Disease?


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About the Book

Although COPD is a major disease world-wide, there is a perplexing current uncertainty about the nature of this disease. COPD is characterised at onset and prevalently by the involvement of the lungs and bronchi, but as the disease evolves, abnormalities develop in other organs and systems and the question arises: what is the pathogenesis of these respiratory and systemic impairments? Are the alterations that occur outside the respiratory system in the course of COPD a direct consequence of the lung pathology or is the lung simply the local expression of a pathological event whose origin lies in the organism as a whole? There is currently a growing debate about whether COPD and all its comorbidities should be considered as a pulmonary disease with systemic implications or whether it should come under a new umbrella term -- chronic systemic inflammatory syndrome -- because the systemic effects of smoking contribute to several other conditions, including cardiovascular disease, some cancers, and increased blood pressure.

Table of Contents:
Introduction; The pathophysiological basis of COPD; COPD and systemic inflammation: myth or reality?; Biomarkers of systemic involvement in stable COPD: do they exist?; Discussion in-depth of topics presented in the morning, with a view to reaching a Consensus or Dissension; Biomarkers of systemic involvement in acute exacerbations of COPD: is there overwhelming evidence?; Science at the Bedside. Is COPD a respiratory disease with prominent systemic implications or a systemic condition with pulmonary symptoms?; Approach to COPD: respiratory or systemic treatment?; Guidelines and clinical practice: myth or reality?; Discussion in-depth of topics presented in the morning, with a view to reaching a Consensus or Dissension Discussion; Summing up and final remarks; Index.


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Product Details
  • ISBN-13: 9781608760510
  • Publisher: Nova Science Publishers Inc
  • Publisher Imprint: Nova Science Publishers Inc
  • Height: 180 mm
  • No of Pages: 282
  • Weight: 574 gr
  • ISBN-10: 1608760510
  • Publisher Date: 01 Jul 2010
  • Binding: Hardback
  • Language: English
  • Returnable: N
  • Width: 260 mm


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