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Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Pathology > Medical microbiology and virology > Hepatitis B and D Protocols: v.2 Immunology,Model Systems,and Clinical Studies
Hepatitis B and D Protocols: v.2 Immunology,Model Systems,and Clinical Studies

Hepatitis B and D Protocols: v.2 Immunology,Model Systems,and Clinical Studies


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About the Book

For volume 2: A broad-ranging collection of cutting-edge techniques for the study of HBV and HDV infections and for the development of therapies to treat them. In this second of two volumes, immunology, Model Systems, and Clinical Studies, the authors focus on protocols for the study of host immune responses to infection, in vitro and in vivo models of infection, and the development of antivirals. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle underlying the technique, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. An accompanying first volume, Detection, Genotypes, and Characterization, contains user-friendly protocols for the identification and quantification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle. For both volumes:

Table of Contents:
Part I. Viral-Specific Immunological and Other Host Responses; Studying Host Immune Responses Against Duck Hepatitis B Virus Infection Darren S. Miller, Edward M. Bertram, Catherine A. Scougall, Ieva Kotlarski, and Allison R. Jilbert; Measurement of Cell-Mediated Immune Response in Woodchucks Stephan Menne and Paul J. Cote; Study of Liver-Specific Expression of Cytokines During Woodchuck Hepatitis Virus Infection Mengji Lu and Michael Roggendorf; Induction of Anti-Hepatitis B Virus Immune Responses Through DNA Immunization Michael Geissler, Robert Weth, Christian F. Grimm, Dorte Ortmann, and Hubert E. Blum; Monitoring Gene Expression Using DNA Microarrays During Hepatitis B Virus Infection Michael R. Beard and Stephen Locarnini; Determination of Hepatitis B Virus-Specific CD8+ T-Cell Activity in the Liver Michelina Nascimbeni and Barbara Rehermann; Determining the Precursor Frequency of HBV Nucleocapsid Antigen-Specific T Cells Jennifer A. Waters and Howard C. Thomas; Detection and Characterization of Virus-Specific CD8+ T Cells Using the Tetramer Approach Xiao-Song He and Harry B. Greenberg; In Vitro Analysis of Hepatitis B Virus Specific CD4+ T Cells Shilpa Chokshi and Nikolai V. Naoumov; Induction of Humoral and Cellular Immune Responses to Hepatitis Delta Virus Through DNA Immunization in BALB/c Mice Ren-Shiang Lee, Shih-Jer Hsu, Li-Rung Huang, Hui-Lin Wu, Shiou-Lin Lin, Ding-Shinn Chen, and Pei-Jer Chen; Part II. In Vitro and In Vivo Models; Infection of Primary Chimpanzee Hepatocytes with Recombinant Hepatitis D Virus Particles: A Surrogate Model for Hepatitis B Virus Azeneth Barrera and Robert E. Lanford; Study of the Endocytosis and Intracellular Localization of Subviral Particles of Hepatitis B Virus in Primary Hepatocytes Dieter Glebe and Wolfram H. Gerlich; The Tupaia Model for the Study of Hepatitis B Virus: Direct Infection and HBV Genome Transduction of Primary Tupaia Hepatocytes Fritz von Weizsacker, Josef Kock, Sabine MacNelly, Shaotang Ren, Hubert E. Blum, and Michael Nassal; Delivery of Hepatitis B Virus Therapeutic Agents Using Asialoglycoprotein Receptor-Based Liver-Specific Targeting Masayoshi Konishi, Catherine H. Wu, and George Y. Wu; Woodchuck Hepatitis Virus Hepatocyte Culture Models Norma D. Churchill and Tomasz I. Michalak; Duck Hepatitis B Virus Primary Hepatocyte Culture Model Olivier Hantz and Fabien Zoulim; Enhancement of Infection of HepG2 Cells in Culture by Predigestion of Hepadnavirus with V8 Protease Xuanyong Lu and Timothy M. Block; Construction of Recombinant Adenoviruses that Produce Infectious Hepatitis B Virus Martin Sprinzl, Jerome Dumortier, and Ulrike Protzer; Baculovirus-Mediated Gene Transfer for the Study of Hepatitis B Virus Harriet C. Isom, Ayman M. Abdelhamed, John P. Bilello, and Thomas G. Miller; Transgenic Hepatitis B Virus Mouse Model in the Study of Chemotherapy John D. Morrey; Transplantation of Human Hepatocytes in Immunodeficient UPA Mice: A Model for the Study of Hepatitis B Virus Jorg Petersen, Martin R. Burda, Maura Dandri, and Charles E. Rogler; Duck Hepatitis B Virus Model in the Study of Hepatitis B Virus Lucyna Cova and Fabien Zoulim; Hepatitis B Virus Transgenic Severe Combined Immunodeficient Mouse Model of Acute and Chronic Liver Disease Mark A. Feitelson, Jonathan D. Larkin, and Raymond F. Schinazi; The Chimpanzee Model: Contributions and Considerations for Studies of Hepatitis B Virus Pascal Gagneux and Elaine A. Muchmore; Hepatitis B in Liver Transplant Recipients as a Special Model of Antiviral Drug Development Robert G. Gish and Adil Wakil; Hepatitis Delta Virus Transfection for the Mouse In Vivo Model Jinhong Chang, Anthony Lerro, and John M. Taylor; Hepatitis Delta Virus RNA Transfection for the Cell Culture Model Thomas B. Macnaughton and Michael M. C. Lai; Part III. Antiviral Testing and Clinical Studies; Analysis of Hepatitis B Virus Dynamics and Its Impact on Antiviral Development Manuel Tsiang and Craig S. Gibbs; Genotyping Anti-Hepatitis B Virus Drug Resistance Eric J. Bourne, Josee Gauthier, Vincent A. Lopez, and Lynn D. Condreay


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Product Details
  • ISBN-13: 9781592596706
  • Publisher: Humana Press Inc.
  • Publisher Imprint: Humana Press Inc.
  • Sub Title: v.2 Immunology,Model Systems,and Clinical Studies
  • ISBN-10: 1592596703
  • Publisher Date: /02/2004
  • Binding: Digital online


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