Iron Transport in Bacteria

provides an up-to-date survey of iron transport systems in bacteria; details iron transport and its regulation in E.colias a prototype for iron transport systems in gram-negative bacteria; includes chapters on the major gram-negative, gram-positive and acid-fast bacterial pathogens - their iron transport systems and the roles of these systems in virulence; presents structural studies of siderophores, heme carriers, and iron transport proteins; discusses the ecology of siderophores and potential therapeutic uses of siderophores.

Table of Contents:
Table of Contents Section I. Siderophores and Hemophores: Properties and Biosynthesis of Bacterial Iron and Heme Carriers 1. Biochemical and Physical Properties of Siderophores, Kenneth N. Raymond and Emily A. Dertz 2. Siderophore Biosynthesis in Bacteria, Christopher T. Walsh and Gary Marshall 3. Hemophore-Dependent Heme Acquisition Systems, Laurent Debarbieux and Cecile Wandersman Section II. Iron Transport Proteins: Structural Studies 4. Structure of Outer Membrane Receptor Proteins, Dick van der Helm 5. Bacterial Heme and Hemoprotein Receptors, Donna Perkins-Balding, Andrew Rasmussen, and Igor Stojiljkovic 6. Bacterial Heme Oxygenases, Melanie Ratliff-Griffin, Angela Wilks, and Igor Stojiljkovic 7. The TonB, ExbB, and ExbD Proteins, Kathleen Postle and Ray A. Larsen 8. Periplasmic Binding Proteins Involved in Bacterial Iron Uptake, Karla D. Krewulak, R. Sean Peacock, and Hans J. Vogel Section III. Iron Transport, Energetics, and Regulation in Escherichia coli K12: a Prototype for Iron Transport Systems in Gram-Negative Bacteria 9. Iron Uptake via the Enterobactin System, Charles F. Earhart 10. Transport Biochemistry of FepA, Phillip E. Klebba 11. Ferrichrome- and Citrate-Mediated Iron Transport, Volkmar Braun, Michael Braun, and Helmut Killman 12. Ferrous Iron Transport, Klaus Hantke 13. Mode of Binding of the Fur Protein to Target DNA: Negative Regulation of Iron-Controlled Transport Gene Expression, Victor de Lorenzo, Jose Perez-Martin, Lucia Escolar, Graziano Pesole, and Giovanni Bertoni Section IV. Iron Transport Systems in Pathogenic Bacteria 14. Pathogenic Escherichia coli, Shigella, and Salmonella, Shelley M. Payne and Alexandra R. Mey 15. Yersinia, Robert D. Perry 16. Vibrio, Manuela Di Lorenzo, Michiel Stork, Alejandro F. Alice, Claudia S. Lopez, and Jorge H. Crosa 17. Neisseria, Cynthia Nau Cornelissen and P. Frederick Sparling 18. Haemophilus, Daniel J. Morton and Terrence L. Stull 19. Pseudomonas, Keith Poole 20. Bordetella, Timothy J. Brickman, Carin K. Vanderpool, and Sandra K. Armstrong 21. Porphyromonas gingivalis, Caroline Attardo Genco, Waltena Simpson, and Teresa Olczak 22. Corynebacterium diphtheriae, Michael P. Schmitt 23. Pathogenic Mycobacteria, G. Marcela Rodriguez and Issar Smith 24. Legionella, Nicholas P. Cianciotto 25. Staphylococcus, Streptococcus, and Bacillus, David E. Heinrichs, Andrea Rahn, Suzanne E. Dale, and Michael Tom Sebulsky 26. Erwinia, a Plant Pathogen, Dominique Expert, Lise Rauscher, and Thierry Franza 27. Therapeutic Uses of Iron (III) Chelators and Their Antimicrobial Conjugates, Vinay Girijavallabhan and Marvin J. Miller Section V. Iron Transport and Ecology 28. Ecology of Siderophores, Gunther Winkelmann 29. Environmental Fluorescent Pseudomonas and Pyoverdine Diversity: How Siderophores Could Help Microbiologists in Bacterial Taxonomy, Jean-Marie Meyer and Valerie Geoffroy 30. Mechanisms and Regulation of Iron Uptake in Rhizobia, Andrew W. B. Johnston