Buy Antibody Engineering Book by Patrick Chames - Bookswagon
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Book 1
Book 2
Book 3
Home > Medicine & Health Science textbooks > Clinical and internal medicine > Diseases and disorders > Immunology > Antibody Engineering: Methods and Protocols(1827 Methods in Molecular Biology)
37%
Antibody Engineering: Methods and Protocols(1827 Methods in Molecular Biology)

Antibody Engineering: Methods and Protocols(1827 Methods in Molecular Biology)


     0     
5
4
3
2
1



Available


X
About the Book

This detailed new edition provides complete and easy access to a variety of antibody engineering techniques.  The volume explores topics such as the generation of native, synthetic, or immune antibody libraries, the selection of lead candidates via the different powerful and innovative display technologies, Fc engineering, as well as their production, characterization, and optimization of antibodies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and up-to-date, Antibody Engineering: Methods and Protocols, Third Edition presents the reader with an extensive toolbox to create the powerful molecules of tomorrow.

Table of Contents:
Antibody Design and Humanization via In Silico Modeling.- Antibody Affinity Maturation by Computational Design.- Use of IMGT® Databases and Tools for Antibody Engineering and Humanization.- Construction of Human Naïve Antibody Gene Libraries.- Construction of Synthetic Antibody Libraries.- Construction of Histidine-Enriched Shark IgNAR Variable Domain Antibody Libraries for the Isolation of pH-Sensitive vNAR Fragments.- Display Technologies for Generation of Ig Single Variable Domains.- A Streamlined Approach for the Construction of Large Yeast Surface Display Fab Antibody Libraries.- Phage Display and Selections on Purified Antigens.- Selection of Antibodies to Transiently Expressed Membrane Proteins Using Phage Display.- Selection of Antibody Fragments against Structured DNA by Phage Display.- Selection of Antibody Fragments by Yeast Display.- Rapid Selection of High Affinity Antibody scFv Fragments Using Ribosome Display.- In Vitro Selection of Single Domain Antibody (VHH) Using cDNA Display.- Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood.- Expression of IgG Monoclonals with Engineered Immune Effector Functions.- An IRES-Mediated Tricistronic Vector for Efficient Generation of Stable, High Level Monoclonal Antibody Producing CHO DG44 Cell Lines.- Production, Purification, and Characterization of Antibody-TNF Superfamily Ligand Fusion Proteins.- Chemoenzymatic Defucosylation of Therapeutic Antibodies for Enhanced Effector Functions Using Bacterial α-Fucosidases.- Fc Glyco- and Fc Protein-Engineering: Design of Antibody Variants with Improved ADCC and CDC Activity.- Fc Engineering: Tailored Synthetic Human IgG1-Fc Repertoire for High Affinity Interaction with FcRn at pH 6.0.- Measuring Antibody-Antigen Binding Kinetics Using Surface Plasmon Resonance.- Parallel Evolution of Antibody Affinity and Thermal Stability for Optimal Biotherapeutic Development.- The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies.- Selection and Use of Intracellular Antibodies.- Site-Specific Radioactive Labeling of Nanobodies.


Best Sellers


Product Details
  • ISBN-13: 9781493986477
  • Publisher: Humana Press Inc.
  • Publisher Imprint: Humana Press Inc.
  • Edition: Revised edition
  • Language: English
  • Returnable: Y
  • Spine Width: 12 mm
  • Weight: 1228 gr
  • ISBN-10: 1493986473
  • Publisher Date: 09 Sep 2018
  • Binding: Hardback
  • Height: 254 mm
  • No of Pages: 543
  • Series Title: 1827 Methods in Molecular Biology
  • Sub Title: Methods and Protocols
  • Width: 178 mm


Similar Products

Add Photo
Add Photo

Customer Reviews

REVIEWS      0     
Click Here To Be The First to Review this Product
Antibody Engineering: Methods and Protocols(1827 Methods in Molecular Biology)
Humana Press Inc. -
Antibody Engineering: Methods and Protocols(1827 Methods in Molecular Biology)
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Antibody Engineering: Methods and Protocols(1827 Methods in Molecular Biology)

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept


    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!