Next-Generation Sequencing Data Analysis
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Next-Generation Sequencing Data Analysis

Next-Generation Sequencing Data Analysis


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About the Book

A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi

Table of Contents:
Introduction to Cellular and Molecular Biology: The Cellular System and the Code of Life. DNA Sequence: The Genome Base. RNA: The Transcribed Sequence. Introduction to Next-Generation Sequencing (NGS) and NGS Data Analysis: NGS Technologies: Ins and Outs. Early-Stage NGS Data Analysis: Common Steps. Computing Needs for NGS Data Management and Analysis. Application-Specific NGS Data Analysis: Transcriptomics by RNA-Seq. Small RNA Sequencing. Genotyping and Genomic Variation Discovery by Whole Genome Resequencing. De novo Genome Assembly from NGS Reads. Mapping Protein-DNA Interactions with ChIP-Seq. Epigenomics and DNA Methylation Analysis by NGS. Metagenome Analysis by NGS. The Changing Landscape of NGS Technologies and Data Analysis: What Is Next for NGS? Appendices. References. Index.

About the Author :
Dr. Xinkun "Sequen" Wang is the director of the NUSeq Core Facility and research associate professor in the Department of Biochemistry and Molecular Genetics at Northwestern University. He was previously an associate research professor of neurogenomics in the Higuchi Biosciences Center and Department of Pharmacology and Toxicology at the University of Kansas, where he was also the director of the Genomics Facility and Genome Sequencing Core. Dr. Wang's research focuses on unraveling genomic changes that underlie neurodegeneration in brain aging and neurodegenerative diseases, such as Alzheimer's disease.


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Product Details
  • ISBN-13: 9781482217896
  • Publisher: Taylor & Francis Ltd
  • Publisher Imprint: CRC Press
  • Language: English
  • ISBN-10: 1482217899
  • Publisher Date: 06 Apr 2016
  • Binding: Digital (delivered electronically)


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