Botulinum Toxins: Cosmetic and Clinical Applications

Botulinum Toxins: Cosmetic and Clinical Applications provides a comprehensive and in-depth review of the use of botulinum toxin for aesthetic procedures and medical applications as a stand-alone treatment and as part of combination therapy. Now a mainstay of cosmetic dermatologic practice, the range of available toxins and their varied applications has grown considerably in recent years requiring the practitioner to carefully consider what approach best suits the needs of their patient. This new book, written by international expert authors, provides guidance to help you refine your technique, add new procedures to your practice, and provide optimal results. This book: Offers guidance on best-practice approaches with botulinum toxin, helping create cutting edge, tailored treatment plans for each patient Benefits from a wealth of color images, procedural videos, and expert tips and tricks Takes a region oriented approach, providing guidance on treatment of the; glabella, forehead, periocular and perioral areas, and contouring of the lower face and lower leg and calf, and neck rejuvenation Contains a thorough review of non-cosmetic treatments such as correction of facial asymmetry, and treatment of axillary hyperhidrosis, plus palm, sole, and craniofacial hyperhidrosis Covers exciting new topics, such as future injectables, topical botulinum toxin, and facial contouring including treatment for benign masseter hypertrophy Discusses combination therapy of botulinum toxin with other non-surgical procedures such as hyaluronic acid (HA) or filler substances, light and laser sources, and other energy-based therapies Includes considerations for darker skin types Offer your patients the best care, stay on top of cutting edge techniques, and avoid pitfalls with coverage of practical tips and real cases. Botulinum Toxins in Dermatology: Cosmetic and Clinical Applications provides best-practice guidance on the contemporary use of botulinum toxin in isolation and in combination.

Table of Contents:
List of Contributors   vii Treatment of the Periocular Area – Crow’s Feet, Brow, and Bunny Lines 165 Girish S. Munavalli, MD (MHS, FACMS), Anthony V. Benedetto, DO (FACP, FCPP), Brian S. Biesman, MD (FACS), and Carolee M. Cutler Peck, MD About the Companion Website   xiii         Video Table of Contents   xv       1 History of Botulinum Toxin for Medical and Aesthetic Use 1      Alastair Carruthers, FRCPC and Jean Carruthers, MD (FRCS(C), FRCOphth)           2 Anatomy and Aesthetic Principles   13 Timothy M. Greco, MD (FACS), Che´rie M. Ditre, MD, and David M. Ozog, MD (FAAD, FACMS)    3 Botulinum Toxin: From Molecule to Medicine 37            Conor J. Gallagher, PhD and Alan Ackerman, PhD            4 Myobloc   53 Neil S. Sadick, MD (FACP, FAAD, FAACS, FACPh) and Suveena Manhas-Bhutani, MD       5 Abobotulinumtoxin: Development and Aesthetic Usage 65 Gary D. Monheit, MD     6 IncobotulinumtoxinA (Xeomin®/Bocouture®)   79 Ulrich Ku¨hne, MD (DALM) and Matthias Imhof, MD (DALM)      7  Future Injectable Toxins 97 Michael H. Gold, MD      8 Reconstitution, Dilution, Diffusion, and Migration of Botulinum Toxin  109 Murad Alam, MD (MSCI, MBA), Hayes B. Gladstone, MD, and David M. Ozog, MD (FAAD, FACMS)          9 Patient Selection 121 Ryan M. Greene, MD (PhD, FACS), John P. Arkins, BS, and Steven H. Dayan, MD (FACS) 10 Treatment of the Glabella   133 Neal D. Varughese, MD (MBA) and David J. Goldberg, MD (JD)  11  Treatment of the Forehead 147 Joel L. Cohen, MD (FAAD, FACMS) and Ramin Fathi, MD 12 Treatment of the Periocular Area - Crow's Feet, Brow and Bunny Lines Girish S. Munavalli, MD(MHS, FACMS), Antony V. BEnedetto, DO (FACP, FCPP), Brian S. Biesman, MD (FACS), and Carolee M. Cutler Peck, MD 13 Contouring of the Lower Face and of the Lower Leg and Calf   177 Mee young Park, MD (PhD), Dennis A. Porto, MD, and Ki Young Ahn, MD (PhD)                14  Treatment of the Perioral Area 191 Shawn Allen, MD (FAAD, FACMS), Roberta Sengelmann, MD, and Rachel Simmons, MD (FAAD)                15 Neck Rejuvenation   199 Koenraad De Boulle, MD, Lakhdar Belhaouari, MD, and Julia D. Kreger, MD         16  Correction of Facial Asymmetry 213 Scott Rickert, MD (FACS), Lesley F. Childs, MD, and Andrew Blitzer, MD (DDS, FACS)         17  Complications and Diffusion   221 Matteo C. LoPiccolo, MD, Farhaad R. Riyaz, MD, and David M. Ozog, MD (FAAD, FACMS)             18 Combination Therapy of Botulinum Toxin with other Nonsurgical Procedures 233 Amy Forman Taub, MD and Lauren Fine, MD (FAAD)      19 Peri-Procedure Botulinum Toxin for Skin Cancer Patients and Scars   253 Timothy Corcoran Flynn, MD, Molly C. Powers, MD, and David M. Ozog, MD (FAAD, FACMS)      20 Achieving a Natural Look   263 Doris Hexsel, MD, Camile L. Hexsel, MD (FAAD, FACMS), and Carolina Siega, BSc                21 Special Considerations in Darker Skin   275 Chere´ Lucas Anthony, MD and Marta I. Rendon, MD (FAAD, FACP)         22 Axillary Hyperhidrosis   285 Ada Regina Trindade de Almeida, MD, Joel L. Cohen, MD (FAAD, FACMS), and Chinobu Chisaki, MD        23 Primary Focal Palm, Sole, Craniofacial, and Compensatory Hyperhidrosis 299 Dee Anna Glaser, MD and Adam R. Mattox, DO (MS)     24  Topical Botulinum Toxin 317 Richard G. Glogau, MD and Eileen Axibal, MD    25  Exciting New Uses of Botulinum Toxin Type A: Dermatology/Dermatologic Surgery and Beyond  329 Donna Bilu Martin, MD (FAAD) and Stephen Mandy, MD (FAAD)              26 Modulating Affect and Mood with Botulinum Toxin Injections: Psychosocial Implications of Neuromodulators  345 James L. Griffith, MD (MSci), Kevin C. Smith, MD (FRCPC (DERM)), and Murad Alam, MD (MSCI, MBA)   27  OnabotulinumtoxinA (Botox®) in Dermatology 357 Jason J. Emer, MD, Eileen Axibal, MD, Ellen S. Marmur, MD (FAAD), and Heidi Waldorf, MD          Index 369

About the Author :
Joel L. Cohen MD, Director, AboutSkin Dermatology and DermSurgery (Greenwood Village and Lone Tree, Colorado); Associate Clinical Professor, University of Colorado Department of Dermatology, CO, USA, and; Assistant Clinical Professor, University of California Irvine Department of Dermatology, CA, USA David M. Ozog MD, Chair, Department of Dermatology, C.S. Livingood Chair of Dermatology, and Director of Cosmetic Dermatology, Henry Ford Hospital; Assistant Professor, Wayne State University, Detroit, MI, USA Dennis A. Porto MD, (Video Editor), Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA