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The Exstrophy—Epispadias Complex: Research Concepts and Clinical Applications

The Exstrophy—Epispadias Complex: Research Concepts and Clinical Applications


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About the Book

This book contains the most up-to-date scientific information on the anatomy, physiology, and pathophysiology of the bladder muscle, nerves, and collagen in the patient with bladder exstrophy. In addition, this book covers the most modern surgical treatment of the infant born with bladder exstrophy and those who fail initial reconstruction. Chapters are contributed by major children's centers throughout the world. The aims of this book are to familiarize both the resident and the experienced practitioner with the most modern methods for the treatment for bladder exstrophy and epispadias. This book deals with the function, innervation, and pathophysiology of the bladder muscle in the patient born with bladder exstrophy. New concepts from leading laboratories around the world regarding the function of the bladder are discussed. In addition, experts offer their advice, expertise, and thoughts concerning the management of the patient born with bladder exstrophy. This book is intended for researchers who are interested in both the innervation, structure and function of bladder muscle and for pediatricians, pediatric surgeons, pediatric orthopedic surgeons, and both adult and pediatric urologists who deal with patients from birth until adult life who are born with bladder exstrophy. This is the first book to deal specifically with the basic science of bladder exstrophy and the clinical management of the bladder exstrophy-epispadias complex.

Table of Contents:
1. The Embryology and Epidemiology of Bladder Exstrophy.- 2. Prenatal Diagnosis of Bladder and Cloacal Exstrophy and Related Conditions.- 3. Anatomy and Biomechanics of the Pelvis in Exstrophy.- 4. Detrusor Morphology and Innervation in Bladder Exstrophy: A Preliminary Investigation.- 5. The Response of the Bladder Smooth Muscle to Increased Bladder Neck Resistance.- 6. Muscarinic Cholinergic Receptors in Bladder Exstrophy: Pharmacological Observations Supporting Functional Closure and Subsequent Bladder Neck Reconstruction.- 7. A Quantitative Histological Analysis of the Bladder in Classical Bladder Exstrophy in Various Stages of Reconstruction Utilizing Color Morphometry.- 8. Analysis of Smooth Muscle and Collagen Subtypes in the Normal Newborn and Bladder Exstrophy Patient.- 9. A Large Animal Model of Bladder Exstrophy: Observations on Bladder Smooth Muscle and Collagen Content and Function.- 10. Tissue Engineering Techniques For Closure of Bladder Exstrophy: An Experimental Animal Model.- 11. Surgical Principles in the Primary Closure of Bladder Exstrophy.- 12. Anterior and Posterior Innominate Osteotomy in Exstrophy Repair.- 13. Bladder Exstrophy Closure without Osteotomy in Philadelphia.- 14. Bilateral Anterior Pubic Osteotomy in Bladder Exstrophy Closure.- 15. The Failed Exstrophy Closure: Strategies for Management—the Johns Hopkins Experience.- 16. Applications of Ureterosigmoidostomy in Bladder Exstrophy.- 17. Cystoplasty in Bladder Exstrophy: Indications and Techniques.- 18. Bladder Exstrophy: Therapeutic Alternatives.- 19. Penile Length in Adulthood after Exstrophy Reconstruction.- 20. Complete Penile Disassembly for Epispadias Repair.- 21. The Cantwell-Ransley Epispadias Repair in Exstrophy/Epispadias: Lessons Learned.- 22. The Impact of Urodynamics onSurgery for Incontinence in Children with Exstrophy.- 23. The Use of Sub-Mucosal Collagen in the Small Bladder Associated with Bladder Exstrophy.- 24. Review of Long-Term Results of Staged Functional Reconstruction and Bladder Neck Plasty in Bladder Exstrophy Patients Followed from Birth at the Johns Hopkins Hospital.- 25. Psychological Aspects of Bladder Exstrophy: Vulnerabilities, Risks, and Protective Factors from a Longitudinal Perspective.- 26. The Outcome of Patients with Classic Bladder Exstrophy in Adult Life.- 27. Long Term Results of Bladder Exstrophy: The London Experience.- 28. Long Term Results of Bladder Exstrophy: The Mainz Experience.- 29. Semen Analysis and Transrectal Ultrasound Findings in Men with Bladder Exstrophy.- 30. Anatomy of Cloacal Exstrophy: The Surgical Implications.- 31. Current Urologic Management of Cloacal Exstrophy: Experience with 11 Patients.- 32. Indications and Types of Bladder Augmentation in Cloacal Exstrophy.- 33. Cloacal Exstrophy: Experience with 41 Cases from 1976–1997.


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Product Details
  • ISBN-13: 9781441933188
  • Publisher: Springer-Verlag New York Inc.
  • Publisher Imprint: Springer-Verlag New York Inc.
  • Height: 254 mm
  • No of Pages: 252
  • Sub Title: Research Concepts and Clinical Applications
  • ISBN-10: 1441933182
  • Publisher Date: 03 Dec 2010
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Width: 178 mm


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