This new edition of the benchmark text on clinical pediatric endocrinology still remains at the forefront of world clinical opinion. Furthermore, the style, which has been the hallmark of the book for the last 20 years, has been maintained for this Fifth Edition.
New features of this Fifth Edition include:
- Special new chapters cover the fetal origins of adult disease and the
endocrine consequences and management of critical illness
- Now opens with a basic science section summarizing the mechanisms of hormone action, genomics, proteomics and the application of molecular biology to clinical practice
- Two new co-editors have been introduced – Peter Clayton and Rosalind Brown
- Every chapter has been updated
Table of Contents:
1. Genetics and genomics. Peter Kopp.
2. Principles of hormone action.
Melissa Westwood.
3. Measuring hormones, molecular tests and their clinical application.
Jan-Maarten Wit, Marcel Karperien, Bart Ballieux.
4. Congenital Disorders Of The Hypothalamo-Pituitary-Somatotrope Axis.
Ameeta Mehta, Evelien Gevers, Mehul Dattani.
5. Acquired Disorders of the Hypothalamo-Pituitary axis.
Kyriaki-Sandy Alatzoglou, Mehul Dattani.
6. Evaluation of growth disorders.
Jerry Wales.
7. Management of Disordered Growth.
Steven Chernausek.
8. Evaluation and Management of Late Effects of Cancer Treatment.
Helena Gleeson, Stephen Shalet.
9. Evaluation and Management of Disorders of Sex Development.
Ieuan Hughes.
10. Evaluation of Disordered Puberty.
Mehul Dattani, Vaitsa Tziaferi, Peter Hindmarsh.
11. Management of Disordered Puberty.
Jakub Mieszczak, Christopher Houk, Peter Lee.
12. The thyroid.
Rosalind Brown.
13. The adrenal cortex and its disorders.
Walter Miller.
14. Polyglandular syndromes.
Catherine Owen, Timothy Cheetham, Simon Pearce.
15. Disorders of water balance.
David Repaske.
16. The Parathyroid and Disorders of Calcium and Bone Metabolism.
Jeremy Allgrove.
17. Endocrine neoplasia in childhood.
Joanne Blair.
18. Diabetes Mellitus.
Joseph Wolfsdorf, Andrew Norris.
19. Hypoglycemia: assessment and management.
Andrew Cotterill, David Cowley, Ristan Greer.
20. Childhood Obesity.
Michael Freemark.
21. Polycystic ovarian syndrome.
M. Isabel Hernandez, Verónica Mericq.
22. Weight regulation and monogenic obesity.
I. Sadaf Farooqi.
23. Fetal growth and early-life origins of disease.
Wayne Cutfield.
24. Ethical issues in clinical paediatric endocrinology.
Leena Patel , Peter Clayton
About the Author :
Professor Charles Brook MA, MD, FRCP, FRCPCH, was the founder and first director of the London Centre for Paediatric Endocrinology at Great Ormond Street and The Middlesex Hospitals. His professorial chair of Paediatric Endocrinology at University College London was the first academic appointment in this subject in UK.
He is the author of more than 300 papers and the author or editor of 13 books. Now retired from the NHS and University, Professor Brook provides a consultation service offering opinion on all aspects of endocrine disease in children and adolescents.
Professor Peter Clayton BSc, MD(Manchester), MRCP, FRCPCH, is Professor of Paediatric Endocrinology & Child Health at the Academic Unit of Child Health and Human Development and Reproductive Health Academic Group and consultant paediatric endocrinologist at Royal Manchester Childrens Hospital, UK
Professor Rosalind Brown, MD, received her bachelor’s degree and medical degree from McGill University in Montreal, Quebec. She is an active staff member at Children’s Hospital Boston in Massachusetts, and is a consulting staff member at MetroWest Medical Center. At Children’s Hospital Boston, Dr. Brown is the director of Clinical Trial Research (Endocrinology), the coordinator of the Clinical Research Conference, Endocrine Division, the Children’s Hospital Boston liaison for the Inter-Hospital Thyroid Conference, and serves as chair of the Career Development Workshop Subcommittee, Endocrine Division.
Dr. Brown is a member of the Board of Directors for Endocrine Education, and she is a member of the Public Health Committee of the American Thyroid Association. Dr. Brown has published over 35 articles, has written 20 book chapters, serves on the editorial board for Thyroid, and is an ad hoc reviewer for Endocrinology, Journal of Clinical Endocrinology & Metabolism, Journal of Clinical Investigation, Journal of Immunological Methods, Journal of Pediatrics, Pediatrics, Science, and Thyroid.
Review :
On the previous editions:
"... I thoroughly enjoyed reading the text, and would highly recommend to all paediatricians with an interest in growth and endocrine problems in childhood." -Trends in Endocrinology and Metabolism
"This book stands alone in its field..."
The Lancet
"Brook's discrimination in selecting contributors and his editorial skills are evident in the book's consistently high quality and smooth readability"
The New England Journal of Medicine
"Controversial issues are well handled"
Medical Journal of Australia
"...a major contribution to the literature on paediatric endocrinology"
Archives of Disease in Childhood
