The Philadelphia Guide: Inpatient Pediatrics

The Philadelphia Guide: Inpatient Pediatrics brings you the latest guidelines, procedures, and treatment and management strategies for inpatient pediatric care. The field of pediatric hospital medicine is rapidly growing and this handbook focuses specifically on caring for pediatric patients in the hospital setting. The Philadelphia Guide: Inpatient Pediatrics addresses over 350 commonly encountered inpatient pediatric medical conditions. Unlike other handbooks, it goes beyond diagnostic strategies to include complete treatment and management guidelines. The focus on the treatment of so many inpatient pediatric medical conditions means that it can be used by everyone who cares for pediatric patients in the hospital‰medical students, residents, and pediatric attendings. Additionally, the organization of the book makes it immensely accessible. The clinical sections are alphabetized and subheadings are consistent throughout the book to make finding information quick and easy. Readers will have rapid access to tables listing pediatric dosages for emergency, airway, and rapid sequence intubation medications, as well as defibrillation and cardioversion protocols. Classic and current evidence-based references are included. Invaluable appendices cover normal vital signs, neonatal codes, and PALS algorithms. A fresh, new approach to pediatric literature, this indispensable handbook offers concise, precise information for healthcare practitioners of all levels, from all disciplines, involved in the care of children in the inpatient setting.

Table of Contents:
About the Editors Contributors Reviewers Preface Foreword 1. ADOLESCENT MEDICINE Krishna Wood, MD, Leonard J. Levine, MD, Marina Catallozzi, Donald F. Schwarz, MD, MPH Anorexia Nervosa Dysfunctional Uterine Bleeding Emergency Contraception Pelvic Inflammatory Disease 2. ALLERGY AND ASTHMA Erin E. McGintee, MD, Nicholas A. Pawlowski, MD Anaphylaxis Asthma Serum Sickness Urticaria/Angioedema 3. ANALGESIA AND SEDATION Suzanne Beno, MD, FRCPC, Jimmy W. Huh, MD Analgesia Assessment of Pain Local Anesthesia Narcotic Analgesics Non-Narcotic Analgesics Non-Pharmacologic Methods of Analgesia Patient Controlled Analgesia (PCA) Sedation Preparation for Sedation Pre-Procedure Sedation Suggestions Post Procedure 4. CALCULATIONS Gary Frank, MD, MS Alveolar - Arterial Oxygen Gradient Absolute Neutrophil Count Anion Gap (Serum) Biostatistics Body Mass Index Body Surface Area (Mosteller Method) Conversions Corrected QT Interval (QTc) Corrected Serum Calcium (for Low Albumin) Corrected Serum Sodium (for Hyperglycemia) Creatinine Clearance (from Timed Urine Collection) Creatinine Clearance (Schwartz Method) Fractional Excretion of Sodium Free Water Deficit Glomerular Filtration Rate (Schwartz Formula) Glucose Infusion Rate Mean Arterial Pressure Osmolality (Serum) 5. CARDIOLOGY Gary Frank, MD, MS, Sara K. Pasquali, MD, Larry A. Rhodes, MD Congenital Heart Disease Aortic Stenosis Atrial Septal Defect Coarctation of the Aorta Endocardial Cushion Defect Hypoplastic Left Heart Syndrome Tetralogy of Fallot Total Anomalous Pulmonary Venous Return Transposition of the Great Arteries Tricuspid Atresia Truncus Arteriosus Ventricular Septal Defect Surgeries for Congenital Heart Disease Acquired Heart Disease Congestive Heart Failure Endocarditis Endocarditis Prophylaxis Myocarditis Pericarditis Electrocardiography Precordial Lead Placement Rate Rhythm Axis P wave PR Interval QRS Complex QT Interval ST Segment T Wave Left Ventricular Hypertophy, ECG signs Right Ventricular Hypertrophy, ECG signs Arrhythmias Atrial Fibrillation Atrial Flutter Atrioventricular Block Long QT Syndrome Premature Atrial Contraction Premature Ventricular Contraction Supraventricular Tachycardia Syncope Ventricular Fibrillation Ventricular Tachycardia Wolff-Parkinson-White Syndrome 6. DERMATOLOGY Sogol Mostoufi-Moab, MD, Albert C. Yan, MD Blistering Disorders Necrotizing Fasciitis Staphylococcal Scalded Skin Syndrome Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Exanthems Acute Urticarial Hypersensitivity Erythema Multiforme (Minor) Vascular Phenomena Complicated Hemangiomas 7. EMERGENCY MEDICINE Andrea Dahlman, MD, Mark D. Joffe, MD Primary and Secondary Survey Primary Survey Secondary Survey Selected Topics in Emergency Medicine Burns Closed Head Injury Concussion Drowning and Near Drowning Hypothermia 8. ENDOCRINOLOGY Francis M. Hoe, MD, Malaka B. Jackson, MD, Adda Grimberg, MD, FAAP Diabetes Mellitus and Diabetic Ketoacidosis Diabetes Mellitus Diabetic Ketoacidosis Hypothalamic-Pituitary-Adrenal Axis Adrenal Insufficiency Congenital Adrenal Hyperplasia Cushing Syndrome Thyroid Disease Congenital Hyperthyroidism Graves Disease Other Selected Topics Cerebral Salt Wasting Diabetes Insipidus Hypoglycemia Rickets Syndrome of Inappropriate Antidiuretic Hormone Tanner Staging 9. FLUIDS AND ELECTROLYTES Gary Frank, MD MS, Vijay Srinivasan, MD, Lisa B. Zaoutis MD Fluid Therapy Maintenance Fluid Therapy Replacement Fluid Therapy Electrolyte Abnormalities Hypocalcemia Hypercalcemia Hypokalemia Hyperkalemia Hyponatremia Hypernatremia 10. GASTROENTEROLOGY Rose C. Graham-Maar, MD, Heather Morein French, MD, David A. Piccoli, MD Esophagus and Stomach Gastroesophageal Reflux Disease Peptic Ulcer Disease Hepatobiliary System Alagille Syndrome Alpha1-Antitrypsin Deficiency Autoimmune Hepatitis Biliary Atresia Gallbladder Disease Glycogen Storage Disease Wilson Disease Small and Large Intestine Celiac Disease Constipation Gastrointestinal Bleeding Inflammatory Bowel Disease Meckel Diverticulum Pancreas Pancreatitis 11. GENETICS Trevor L. Hoffman, MD, PhD, Alix Seif, MD, MPH, Matthew Deardorff, MD, PhD, Paige B. Kaplan, MD, Ian Krantz, MD Beckwith-Wiedemann Syndrome Marfan Syndrome Neurofibromatosis Type 1 Trisomy 13 Trisomy 18 Trisomy 21 Turner Syndrome 12. HEMATOLOGY Char Witmer, MD, Leslie Raffini, MD Anemia Red Blood Cell Indices Differential Diagnosis Based on MCV Glucose-6-Phosphate Dehydrogenase Deficiency Hereditary Spherocytosis Iron Deficiency Anemia Sickle Cell Disease Thalassemias Transient Erythroblastopenia of Childhood Bleeding Disorders Coagulation Studies Hemophilia Vitamin K Deficiency Von Willebrand Disease Thrombocytopenia Differential Diagnosis Idiopathic Thrombocytopenic Purpura Thrombotic Disorders Medications for Anticoagulation Thrombosis Transfusion Medicine Cryoprecipitate Transfusion Fresh Frozen Plasma Transfusion Platelet Transfusion Red Blood Cell Transfusion Transfusion Complications 13. HUMAN IMMUNODEFICIENCY VIRUS Deborah Palmer, MD, Richard M. Rutstein, MD, Theoklis Zaoutis, MD Human Immunodeficiency Virus Infection Fever in HIV Post-Exposure Prophylaxis 14. IMMUNOLOGY Manish J. Butte, MD, PhD, Kathleen E. Sullivan, MD, PhD Approach to Primary Immunodeficiency Major Categories Warning Signs Differential Diagnosis of Neutropenia Diagnostic Approach Common Immunodeficiencies 22q Deletion Dyndromes Ataxia-Telangiectasia Chediak-Higashi Syndrome Chronic Granulomatous Disease Common Variable Immunodeficiency Hyper-IgE Recurrent Infection Syndrome Severe Combined Immunodeficiency Wiskott-Aldrich Syndrome X-linked Agammaglobulinemia 15. INFECTIOUS DISEASES Snehal N. Shah, MD, Asim Aminsharif Ahmed, MD, Jason G. Newland, MD, Sarah Armstrong, MD, Louis M. Bell, MD, and Samir S. Shah, MD (with contributions from Michael F. Maraventano,MD, Rose C. Graham-Maar, MD, Heather Morein French, MD, Pamela G. Fitch, MD, and Judit Saenz- Badillos, MD) Syndromes and Complexes Bite Wound Infections Bronchiolitis Cellulitis Croup Encephalitis Gastroenteritis Infectious Mononucleosis Lymphadenitis and Lymphadenopathy Mastoiditis Meningitis Neonatal Conjunctivitis Osteomyelitis Otitis Media Periorbital/Preseptal and Orbital Cellulitis Pneumonia Retropharyngeal and Peritonsillar Abscess Septic Arthritis Sinusitis Toxic Shock Syndrome Urinary Tract Infection Specific Pathogens Cat Scratch Disease Clostridium Difficile Infection Hepatitis A Hepatitis B Hepatitis C Lyme Disease Malaria Neonatal Herpes Simplex Virus Infection Pertussis Rickettsial Diseases Tuberculosis Varicella Zoster Infections Fever and Bacteremia Catheter-Related Bloodstream Infections Fever in Neonates Fever of Unknown Origin 16. METABOLISM Ralph J. DeBerardinis, MD, PhD, Irma Payan, RN, CRNP, Neal Sondheimer, MD, PhD, Can Ficicioglu, MD, PhD Fatty Acid Oxidation Disorders and Disorders of Ketone Metabolism General Mitochondrial Disorders Specific Mitochondrial Disorders Urea Cycle Defects General Urea Cycle Defects Specific Urea Cycle Defects Defects of Amino Acid Metabolism Hereditary Tyrosinemia Type 1 Phenylketonuria Defects of Carbohydrate Metabolism Galactosemia Hereditary Fructose Intolerance Organic Acidemias Branched-Chain Organic Acidurias Primary Lactic Acidosis Respiratory Chain Defects Pyruvate Dehydrogenase Deficiency 17. NEONATOLOGY Laura A. Lawler, MD, Andrea A. Berry, MD, Snehal N. Shah MD, Gary Frank, MD, MS, John Casey MD, CM, Mary Catherine Harris, MD APGAR scores Apparent Life Threatening Event Hemolytic Disease: ABO incompatibility Hemolytic Disease: RH incompatibility Infant of a Diabetic Mother Meconium Aspiration Syndrome Neonatal Hyperbilirubinemia Polycythemia TORCH Infections 18. NEPHROLOGY Christine T. Lauren, MD, Sarbattama Sen, MD, Kristen A. Feemster, MD, MPH, Joanne N. Wood, MD, Charles P. McKay, MD (with contributions from Ann E. Salerno, MD) Glomerular Disease Hemolytic Uremic Syndrome IgA Nephropathy Nephrotic Syndrome Post-Infectious Glomerulonephritis Tubular / Interstitial Disease Renal Tubular Acidosis Rhabdomyolysis Urolithiasis Other Renal Diseases Acute Renal Failure Hematuria Hypertension 19. NEUROLOGY Annapurna Poduri, MD, Renee A. Shellhaas, MD, Dennis J. Dlugos, MD, Peter H. Berman, MD, Gihan I. Tennekoon, MD General Principles Acute Weakness Altered Mental Status Ataxia Brain Death Coma Cranial Nerves Acquired Neurologic Disease Acute Disseminated Encephalomyelitis Acute Myopathy Botulism Guillain-Barre Syndrome Increased Intracranial Pressure Multiple Sclerosis Myasthenia Gravis Pseudotumor Cerebri Spinal Cord Emergency Stroke Transverse Myelitis Seizures and Epilepsy General Principles Febrile Seizures Infantile Spasms Neonatal Seizures Status Epilepticus Unprovoked Seizure, First Unprovoked Seizure, Second 20. NUTRITION Brenda Waber, RD, CSP, CNSD, LDN, Colleen Yanni, MS, RD, LDN, Maria R. Mascarenhas, MBBS and the CHOP Committee of Dietitians Assessment of Nutritional Status Enteral Nutrition (Tube Feeds) Parenteral Nutrition 21. ONCOLOGY Nicholas B. Slamon, MD, Rhonda M. Graves, MD, Leslie S. Kersun, MD Malignancies Abdominal Masses Bone Tumors Brain Tumors Leukemia Lymphoma Rhabdomyosarcoma Oncologic Emergencies Fever and Neutropenia Nausea and Vomiting Spinal Cord Compression Superior Vena Cava Syndrome and Superior Mediastinal Syndrome Tumor Lysis Syndrome 22. OPHTHALMOLOGY Judit Saenz-Badillos, MD, Stefanie L. Davidson, MD Glaucoma Hyphema Leukocoria Orbital Fracture 23. ORTHOPEDICS Denise M. Bell, Jennifer Minarcik Hwang, MD, Stephen Ludwig, MD, and John M. Flynn, MD Fractures Clavicle Fractures Femur Fractures Hand Fractures Lateral Humeral Condyle Fractures Medial Humeral Epicondyle Fractures Physis (Growth Plate) Fractures Proximal Humerus Fractures Supracondylar Fracture of Humerus Common Orthopedic Issues Compartment Syndrome Developmental Dysplasia of the Hip Legg-Calve-Perthes Disease Transient Synovitis 24. OTOLARYNGOLOGY Marc Eisen, MD, PhD, Steven D. Handler, MD, MBE Adenotonsillary Hypertrophy Branchial Cleft Anomalies Cleft Lip/Palate Epistaxis Foreign Body Aspiration/Ingestion Laryngomalacia Tracheostomy Vocal Cord Paralysis 25. PROCEDURES Nicholas Tsarouhas, MD (with contributions from Linda L. Brown, MD, Lauren Daly, MD, Reza Daugherty, MD, Marla J. Friedman, DO, Karen J. O'Connell, MD, Vivian Hwang, MD) Endotracheal Intubation Femoral Venous Catheterization Intraosseous Line Placement Laceration Repair Lumbar Puncture Pneumothorax Needle Decompression Suprapubic Bladder Aspiration Tube Thoracostomy Umbilical Vessel Catheterization 26. PSYCHIATRY Amy Kim, MD, Anthony L. Rostain, MD, MA Agitation/Aggression Psychosis Suicidality 27. PULMONOLOGY David Hehir, MD, Michael F. Maraventano, MD, Suzanne Dawid, MD, PhD, Howard B. Panitch, MD Pulmonary Diseases and Syndromes Acute Respiratory Distress Syndrome Cystic Fibrosis Hemoptysis Obstructive Sleep Apnea Mechanical Ventilation and Pulmonary Assessment Blood Gas Interpretation Mechanical Ventilation Pulmonary Function Tests 28. RHEUMATOLOGY Pamela G. Fitch, MD, Elise R. DeVore, MD, Jeffrey C. Klick, MD, Jon M. Burnham, MD DermatoMyositis Henoch-Schonlein Purpura Juvenile Rheumatoid Arthritis Kawasaki Disease Rheumatic Fever Systemic Lupus Erythematosis 29. SURGERY Amy L. Winkelstein, MD, Mercedes Blackstone, MD, Suzanne Dawid, MD, PhD, Michael Nance, MD (with contributions from James P. Franciosi, MD, MS, Leonard J. Levine, MD, and Gary Frank, MD, MS) Neonatal Surgery Congenital Diaphragmatic Hernia Esophageal Atresia & Tracheoesophageal Fistula Gastroschisis Omphalocele General Surgery Appendicitis Hirschsprung's Disease Inguinal Hernia Intussusception Malrotation and Midgut Volulus Perirectal Abcess Pneumothorax Pyloric Stenosis Urologic Surgery Ovarian Torsion Testicular Torsion 30. TOXICOLOGY Rebecca Collier MD, Diane P. Calello MD, Fred M. Henretig MD Decontamination and Enhanced Elimination Activated Charcoal Cathartics Gastric Lavage Hemodialysis Hemoperfusion Multiple-Dose Activated Charcoal Syrup of Ipecac Whole Bowel Irrigation Specific Poisonings Acetaminophen (APAP) Amphetamines Anti-Histamines Beta Blockers Calcium Channel Blockers Carbamazepine Carbon Monoxide Caustics Clonidine Cocaine Digoxin Ethanol Ethylene glycol Hydrocarbons Iron Isopropyl Alcohol Lead Methanol Opioids Organophosphates Phenothiazines Phenytoin Salicylates (Aspirin) Selective Serotonin Uptake Inhibitors Tricyclic Antidepressants APPENDICES Appendix A: Normal Pediatric Vital Signs Appendix B: Neonatal Code Appendix C: PALS Algorithms Pediatric Bradycardia Algorithm Pediatric Tachycardia Algorithm for Infants and Children with Rapid Rhythm and Adequate Perfusion Pediatric Tachycardia Algorithm for Infants and Children with Rapid Rhythm and Poor Perfusion Pediatric Pulseless Arrest Algorithm Algorithm for Stabilization of Infants and Children after Arrest

Review :
"This is a much needed book. It contains the information needed to make fast, informed decisions. The Philadelphia Guide: Inpatient Pediatrics is much less cumbersome than Rudolf's and much more clinically based than Harriet Lane. I'm anxious to get it in my hands to use it!" - Medicine/Pediatrics Resident, Medical University of South Carolina, Charleston, South Carolina "The Philadelphia Guide: Inpatient Pediatrics is an excellent text. It is well written, easy-to-read, concise, and very complete. The book covers the most important topics encountered by pediatric residents. Topics are presented in a very straightforward and easy-to-understand manner - I've already used some examples to teach my interns and medical students! It included multiple treatment options, medication dosing and other pearls, which are very helpful, especially on the resident and attending staff level." - Internal Medicine and Pediatrics Resident, Tulane University, New Orleans, LA "The strengths of The Philadelphia Guide: Inpatient Pediatrics are its succinctness, the way the subjects are divided into headings, and the thoroughness of the information. There is definitely more specific and detailed information in this book than in the competition. This will be a very helpful and successful book, and a great resource to have on the wards. I would highly recommend this to my colleagues." - Pediatrics Resident, University of California, San Francisco, San Francisco, CA "With the hectic life of a Pediatric resident, this book will be a must. Compared to other texts that are often used in pediatrics, such as Nelson's or Rudolph's, The Philadelphia Guide: Inpatient Pediatrics seems to have as much information about each topic, but it's easier to find and it's better because there is more detail under the treatment sections." - Pediatrics Resident, The University Children's Hospital, University of Medicine and Dentistry, New Jersey, Newark, NJ "Overall, The Philadelphia Guide: Inpatient Pediatrics is a good book that I would recommend. The chapters cover a remarkable amount of material in a very concise manner that is easy to read and follow." - Pediatric Resident, Texas Children's Hospital, Ben Taub General Hospital, Houston, Texas "The Philadelphia Guide: Inpatient Pediatrics allows a good short review of important topics. It is obvious that a lot of work and effort went into it. I would recommend this to my fellow residents." - Medicine-Pediatrics Resident, Los Angeles County - USC Medical Center, Los Angeles, California "The Philadelphia Guide: Inpatient Pediatrics has a different, more clinically useful approach than other books. It gives clear directions for making a diagnosis, and good emphasis on differential diagnosis. One of the things that a resident has to learn to do is to rule in a diagnosis, and so this is a crucial addition to any book of this kind. There are sections here that are not found in other texts of this type (at least that I am aware of), so this will be seen as a valued resource." - Class of 2004, Tulane University, New Orleans, Louisiana "The Philadelphia Guide: Inpatient Pediatrics will be a wonderful addition to any med student or pediatric resident's collection. The information is easily accessible and the format style is terrific. I like the fact that each disease/section is broken down into epidemiology, etiology, differential diagnosis, pathophys, etc. At the attending level, this book may serve as a quick reference guide during rounds on the inpatient ward. The topics and information in this book would have been useful during rounds as a pediatrics resident. In fact, when it comes out I will definitely purchase this book even though I will be in fellowship." - Pediatrics Resident, The University Children's Hospital, University of Medicine and Dentistry, New Jersey, Newark, New Jersey