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Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Dentistry > Adjunctive Use of a Chinese Herbal Medicine in the Non-Surgical Mechanical Treatment of Advanced Periodontal Disease on Smokers: A Randomized Clinical Trial
Adjunctive Use of a Chinese Herbal Medicine in the Non-Surgical Mechanical Treatment of Advanced Periodontal Disease on Smokers: A Randomized Clinical Trial

Adjunctive Use of a Chinese Herbal Medicine in the Non-Surgical Mechanical Treatment of Advanced Periodontal Disease on Smokers: A Randomized Clinical Trial


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About the Book

This dissertation, "Adjunctive Use of a Chinese Herbal Medicine in the Non-surgical Mechanical Treatment of Advanced Periodontal Disease on Smokers: a Randomized Clinical Trial" by Chun-sing, Johnson, Ho, 何晉陞, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract Abstract The aim of this study was to evaluate the adjunctive use of a Chinese herbal medicine with non-surgical periodontal treatment in heavy smokers exhibiting moderate-to- advanced chronic periodontitis. The study was a double-blinded randomized controlled clinical trial last for 6 months. A total of 32 patients, 31 males and 1 female, aged from 31 to 61 years (mean = 43.9) having at least two sites per quadrant with probing pocket depth (PPD) >=5mm were recruited. All the subjects were also screened by a traditional Chinese medical doctor to be suitable for taking the Chinese herbal medicine used in the study. Clinical parameters, including presence of supragingival plaque (Pl%), bleeding on probing (BOP%), probing pocket depth (PPD) and probing attachment level (PAL) were recorded at baseline, 3 months and 6 months after treatment. Standardized intra- oral radiographs were taken at baseline and after 3 and 6 months in 2 sites with PPD >= 5mm and angular bone defects in each patient for evaluation of alveolar bone changes by digital subtraction radiography. After initial examination, Chinese herbal medicine (modified recipe of "Yunu Jian") or placebo were given to patients who were randomly assigned into two groups for 3 months. Test drug and placebo were prepared in dehydrated powder form and sealed in aluminum bags which were coded by the manufacturer. Oral hygiene instructions were given and quadrant-by-quadrant supra- and sub-gingival debridement was performed 1 week later and was completed within 1 month. Patients were then reviewed regularly and reinforcement of oral hygiene instruction and supra- and sub-gingival debridement was performed if needed. Full-mouth Pl% decreased from 88% at baseline to 8% at 6-months while the BOP% decreased from 84% to 20%. Statistically significant changes in reductions of PPD, iAbstract gain in PAL and increase in recession (REC) were seen in both test and control groups at 3- and 6-month examination when compared to baseline (pRadiographical analysis by using computer-assisted densitometric image analysis (CADIA) showed an increase of bone volume and density at investigated sites in both test and control group from baseline to 6-months (pThe findings from the present study suggest that the adjunctive use of this Chinese herbal medicine in Chinese heavy smoking patients with moderate-to-severe chronic periodontitis as an adjunct in non-surgical periodontal therapy does not provide additional clinical benefit. ii DOI: 10.5353/th_b3765158 Subjects: Periodontitis - Treatment Herbs - Therapeutic use Medicine, Chinese


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Product Details
  • ISBN-13: 9781361437308
  • Publisher: Open Dissertation Press
  • Publisher Imprint: Open Dissertation Press
  • Height: 279 mm
  • No of Pages: 96
  • Sub Title: A Randomized Clinical Trial
  • Width: 216 mm
  • ISBN-10: 1361437308
  • Publisher Date: 27 Jan 2017
  • Binding: Hardback
  • Language: English
  • Spine Width: 6 mm
  • Weight: 517 gr


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Adjunctive Use of a Chinese Herbal Medicine in the Non-Surgical Mechanical Treatment of Advanced Periodontal Disease on Smokers: A Randomized Clinical Trial
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