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Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Dentistry > Adjunctive Effect on Hormone Replacement Therapy on Periodontal Treatment Responses in Postmenopausal Women
Adjunctive Effect on Hormone Replacement Therapy on Periodontal Treatment Responses in Postmenopausal Women

Adjunctive Effect on Hormone Replacement Therapy on Periodontal Treatment Responses in Postmenopausal Women


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About the Book

This dissertation, "Adjunctive Effect on Hormone Replacement Therapy on Periodontal Treatment Responses in Postmenopausal Women" by Wing-kwan, Rosa, Yeung, 楊穎筠, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract Abstract The aim of this study was to evaluate if there is any adjunctive effect of hormone replacement therapy (HRT) on non-surgical periodontal therapy in postmenopausal women with moderate to severe chronic periodontitis. The study was carried out as a single-blinded longitudinal study lasting for 12 months. Postmenopausal women with or without any HRT (assigned to test and control groups, respectively) and having at least 4 sites with probing depth >=6 mm were recruited. A total of 30 patients, 15 in the test group (mean age = 51.0 years) and 15 in the control group (mean age = 54.1 years) participated in the study. The mean duration of menopause was 3.9 years for test subjects and 3.0 years in controls. However, only 6-month data were available for 27 of the 30 patients due to time constrains. Therefore, 3-month data from all 30 subjects and 6-month data from 27 subjects were analyzed and presented. Clinical parameters, including presence of supragingival plaque (PI%), bleeding on probing (BOP%), probing pocket depth (PPD) and probing attachment level (PAL) were recorded at baseline, 3-month and 6-month after non-surgical periodontal treatment. Standardized intra-oral radiographs in selected sites for evaluation of alveolar bone changes by digital subtraction radiography were also taken at the same chosen time intervals. After initial examination, oral hygiene instructions were given and full-mouth supra- and sub-gingival debridement were performed. After 6 months, full-mouth Pl% decreased from 75% at baseline to 22%, while the BOP% decreased from 67% at baseline to 26% at 6-month for the test group. The corresponding percentage changes of Pl% for the control group were from 75% to 18%, and 74% to 20% for Abstract BOP%, respectively. Throughout the study, the reduction of PPD, gain in PAL and increase in REC at different time points were found to be statistically significant (pThe findings from the present study suggested that there was no adjunctive clinical benefit of HRT in postmenopausal women when combined with non-surgical periodontal therapy during the treatment of moderate to severe chronic periodontitis. DOI: 10.5353/th_b3765195 Subjects: Hormone therapy


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Product Details
  • ISBN-13: 9781361436233
  • Publisher: Open Dissertation Press
  • Publisher Imprint: Open Dissertation Press
  • Height: 279 mm
  • No of Pages: 96
  • Weight: 245 gr
  • ISBN-10: 1361436239
  • Publisher Date: 27 Jan 2017
  • Binding: Paperback
  • Language: English
  • Spine Width: 5 mm
  • Width: 216 mm


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