The Antiphospholipid Syndrome

About the Book

Written by the foremost researchers in the field, this book gathers together in a single source the many important clinical associations of antiphospholipid antibodies. Antibody-related clotting mechanisms and their relationship to conditions such as recurrent strokes, chorea, multi infarct dementias, a variety of spinal syndromes, Addison's Disease, recurrent miscarriages, and many more are discussed in depth. The importance of these antibodies in 'Primary,' 'Secondary,' and 'Catastrophic' Antiphospholipid Syndrome is highlighted. Each chapter is devoted to a specific internal system and the clinical effects this syndrome has on that system.
This authoritative book is an essential addition to medical libraries as well as an invaluable reference for general physicians, internists, rheumatologists, neurologists, cardiologists, nephrologists, endocrinologists, gastroenterologists, pulmonologists, dermatologists, and obstetricians.

Table of Contents:
1. Epidemiologic and Pathophysiologic Aspects of the Antiphospholipid Syndrome 2. The Antiphospholipid Syndrome: History, Definition, Classification, and Differential Diagnosis 3. Epidemiology of the Antiphospholipid Syndrome 4. Immunology and Methods of Detection of the Antiphospholipid Antibodies 5. Immunogenetics of the Antiphospholipid Syndrome 6. Pathogenesis of the Antiphospholipid Syndrome 7. Animal Models of the Antiphospholipid Syndrome 8. Cytokines in the Antiphospholipid Syndrome 9. Pathology of the Antiphospholipid Syndrome 10. Clinical and Laboratory Features of the Antiphospholipid Syndrome 11. Thrombotic Manifestations in the Antiphospholipid Syndrome 12. Fetal Losses and Other Obstetric Manifestations in the Antiphospholipid Syndrome 13. Cerebral Thrombosis and Other Neurologic Manifestations in the Antiphospholipid Syndrome 14. Cardiac Manifestations in the Antiphospholipid Syndrome 15. Pulmonary Manifestations in the Antiphospholipid Syndrome 16. Renal Manifestations in the Antiphospholipid Syndrome 17. Adrenal, Hepatic, and Other Intraabdominal Manifestations in the Antiphospholipid Syndrome 18. Osteoarticular Manifestations in the Antiphospholipid Syndrome 19. Dermatologic Manifestations in the Antiphospholipid Syndrome 20. Ophthalmic Manifestations in the Antiphospholipid Syndrome 21.Thrombocytopenia and Other Hematologic Abnormalities in the Antiphospholipid Syndrome 22. Immunologic Abnormalities in the Antiphospholipid Syndrome 23. 'Primary,' 'Secondary,' 'Catastrophic,' and other Variants of the Antiphospholipid Syndrome 24. Pediatric' and 'Familial' Antiphospholipid Syndromes 25. The Antiphospholipid Syndrome in Infectious Diseases 26. Management and Prognosis of the Antiphospholipid Syndrome 27. Management of Venous and Arterial Thrombosis in the Antiphospholipid Syndrome 28. Prophylaxis of Fetal Losses in the Antiphospholipid Syndrome 29. Other Aspects of the Management of the Antiphospholipid Syndrome 30. Course and Prognosis of the Antiphospholipid Syndrome 31. New Perspectives in the Study and Treatment of the Antiphospholipid Syndrome.