About the Book
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 47. Chapters: Allan Bradley, Austin Smith (biologist), Big Picture (magazine), Cancer Genome Project, ChEMBL, Chris Frith, COSMIC cancer database, DECIPHER, Diamond Light Source, ELife, Ensembl, Ensembl Genomes, Ewan Birney, Fiona Watt, Francis Crick Institute, Genome Reference Consortium, Geraint Rees, Henry Wellcome, Human Genome Project, James Cuff, John Sulston, Jon Driver, Kay Davies, Leena Peltonen-Palotie, Malawi Liverpool Wellcome Trust, Mark Walport, MEROPS, Michael Stratton, Pfam, Rfam, Richard M. Durbin, Richard Mott (statistician), Science Learning Centres, The London Museums of Health & Medicine, UCL Centre for the History of Medicine, UCL Neuroscience, UK Biobank, Wellcome Collection, Wellcome Library, Wellcome Trust Book Prize, Wellcome Trust Centre for Cell-Matrix Research, Wellcome Trust Centre for Gene Regulation and Expression, Wellcome Trust Centre for Human Genetics, Wellcome Trust Centre for Neuroimaging, Wellcome Trust Centre for Stem Cell Research, Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute, William Castell, WormBase. Excerpt: The Human Genome Project (HGP) is an international scientific research project with a primary goal of determining the sequence of chemical base pairs which make up DNA, and of identifying and mapping the approximately 20,000-25,000 genes of the human genome from both a physical and functional standpoint. The first official funding for the Project originated with the Department of Energy's Office of Health and Environmental Research, headed by Charles DeLisi, and was in the Reagan Administration's 1987 budget submission to the Congress. It subsequently passed both Houses. The Project was planned for 15 years. In 1990, the two major funding agencies, DOE and NIH, developed a memorandum of understanding in order to coordinate plans, and set the clock for initiation of the Project to 1990. At that time David Galas was Director of the renamed "Office of Biological and Environmental Research" in the U.S. Department of Energy's Office of Science, and James Watson headed the NIH Genome Program. In 1993 Aristides Patrinos succeeded Galas, and Francis Collins succeeded James Watson, and assumed the role of overall Project Head as Director of the U.S. National Institutes of Health (NIH) National Human Genome Research Institute. A working draft of the genome was announced in 2000 and a complete one in 2003, with further, more detailed analysis still being published. A parallel project was conducted outside of government by the Celera Corporation, or Celera Genomics, which was formally launched in 1998. Most of the government-sponsored sequencing was performed in universities and research centres from the United States, the United Kingdom, Japan, France, Germany and Spain. Researchers continue to identify protein-coding genes and their functions; the objective is to find disease-causing genes and possibly use the information to develop more specific treatments. It also may be possible to locate patterns in gene expression, which could help physicians glean insight into the body'
