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Home > Art, Film & Photography > Atc-D05: Fumarsaure, Calcitriol, Steinkohlenteer, Xanthotoxin, Dithranol, Bergapten, Methoxsalen
Atc-D05: Fumarsaure, Calcitriol, Steinkohlenteer, Xanthotoxin, Dithranol, Bergapten, Methoxsalen

Atc-D05: Fumarsaure, Calcitriol, Steinkohlenteer, Xanthotoxin, Dithranol, Bergapten, Methoxsalen


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About the Book

Aus Wikipedia. Nicht dargestellt. Auszug: Dithranol (INN) or Anthralin (USAN and former BAN) is a Hydroxyanthrone, anthracene derivative, medicine applied to the skin of people with psoriasis. It is available as creams, ointment or pastes in 0.1 to 2% strengths (Drithocreme, Dithrocream, Zithranol-RR, Micanol, Psorlin, Dritho-Scalp, Anthraforte, Anthranol and Anthrascalp). The terms dithranol and anthralin are sometimes used synonymously. Dithranol accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. In addition Dithranol may act by reducing the elevated levels of cGMP that occurs in psoriasis. Anthralin is a synthetic compound whose precise mechanism of anti-psoriatic action is not yet fully understood. However, numerous studies have demonstrated anti-proliferative and anti-inflammatory effects of anthralin on psoriatic and normal skin. The anti-proliferative effects of anthralin appear to result from both an inhibition of DNA synthesis as well as from its strong reducing properties. Recently, anthralin's effectiveness as an anti-psoriatic agent has also been in part attributed to its abilities to induce lipid peroxidation and reduce levels of endothelial adhesion molecules which are markedly elevated in psoriatic patients. Unlike retinoids and PUVA, anthralin does not inhibit liver microsomal enzyme activity; consequently, the likelihood of adverse drug interactions is greatly reduced when other agents are administered concomitantly with anthralin. More dithranol penetrates into impaired skin in 30 minutes than into intact skin during about 16 hours. For this reason weaker 0.1-0.5% preparations are applied over night, but stronger 1-2% products are applied for between 30 minutes and one hour depending upon the formulation. For ...http: //booksllc.net/?l=d


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Product Details
  • ISBN-13: 9781158753123
  • Publisher: Books LLC
  • Publisher Imprint: Books LLC
  • Height: 152 mm
  • No of Pages: 44
  • Spine Width: 3 mm
  • Weight: 77 gr
  • ISBN-10: 1158753128
  • Publisher Date: 22 Jul 2010
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Sub Title: Fumarsaure, Calcitriol, Steinkohlenteer, Xanthotoxin, Dithranol, Bergapten, Methoxsalen
  • Width: 229 mm


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