About the Book
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 32. Chapters: Carbonic anhydrase inhibitors, Loop diuretics, Osmotic diuretics, Potassium-sparing diuretics, Thiazides, Sorbitol, Topiramate, Zonisamide, Acetazolamide, Metolazone, Furosemide, Cyclothiazide, Brinzolamide, Xipamide, Hydrochlorothiazide, Sultiame, Chlortalidone, Benzamil, Tolvaptan, Bumetanide, Etacrynic acid, Amiloride, Triamterene, Mercurial diuretic, Mafenide, Indapamide, Dorzolamide, Conivaptan, Tienilic acid, Co-amilozide, Bendroflumethiazide, Benzthiazide, Trichlormethiazide, Rolofylline, Cicletanine, Torasemide, Orthosiphon, Methazolamide, Pamabrom, Ozolinone, Piretanide, Co-tenidone, Diclofenamide, Ethanolamine-O-sulfate, Clopamide, Quinethazone, Mozavaptan, Aquaretics, Hydroflumethiazide, Satavaptan, Co-amilofruse, Aldosterone antagonist, Mefruside, Glicaramide, Mersalyl acid, Etozoline, Altizide, Clorexolone, Tripamide, Methyclothiazide, Aminometradine, Muzolimine, Cyclopenthiazide, Hygroton, Meticrane, Mebutizide, Meralluride, Azosemide, Epitizide, Fosinopril/hydrochlorothiazide, Tenoretic, Thiazide-like diuretic. Excerpt: Topiramate (brand name Topamax) is an anticonvulsant (antiepilepsy) drug. It was originally produced by Ortho-McNeil Neurologics and Noramco, Inc., both divisions of Johnson & Johnson. It was discovered in 1979 by Bruce E. Maryanoff and Joseph F. Gardocki during their research work at McNeil Pharmaceutical. Generic versions are available in Canada and were FDA approved in September 2006. Mylan Pharmaceuticals was recently granted final approval for generic topiramate 25, 100, and 200 mg tablets and sprinkle capsules by the FDA for sale in the US. 50 mg tablets were granted tentative approval. The last patent for topiramate in the U.S. was for pediatric use; this patent expired on February 28, 2009. On May 21, 2010, Ortho-McNeil plead guilty and was fined US$6.14 million by the FDA for ...
